AutismKB 2.0

Annotation Detail for HOXA1


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Basic Information Top
Gene Symbol:HOXA1 ( BSAS,HOX1,HOX1F,MGC45232 )
Gene Full Name: homeobox A1
Band: 7p15.2
Quick LinksEntrez ID:3198; OMIM: 142955; Uniprot ID:HXA1_HUMAN; ENSEMBL ID: ENSG00000105991; HGNC ID: 5099
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
209Antp-type hexapeptide.
Location(AA) Modifications Resource
Location(AA) Modification Resource
93Phosphoserine(IKK)HMM predict
103N-linkedHMM predict
108Phosphotyrosine(Jak)HMM predict
177N-linkedHMM predict
178N-linkedHMM predict
181Phosphoserine(CDK)HMM predict
193Phosphoserine(IKK)HMM predict
196Phosphoserine(IKK)HMM predict
196Phosphoserine(CK2)HMM predict
196O-linkedHMM predict
196O-linkedHMM predict
198O-linkedHMM predict
199Phosphoserine(CK1)HMM predict
200Phosphoserine(CDK)HMM predict
200Phosphoserine(CDC2)HMM predict
200Phosphoserine(IKK)HMM predict
235N-linkedHMM predict
255Phosphothreonine(PKC)HMM predict
269N-linkedHMM predict
296Phosphoserine(CDC2)HMM predict
296O-linkedHMM predict
299Phosphothreonine(CDC2)HMM predict
311Phosphoserine(CK1)HMM predict
314Phosphoserine(IKK)HMM predict
317Phosphoserine(IKK)HMM predict
319S-farnesylHMM predict
322Phosphoserine(MAPK)HMM predict
322Phosphoserine(CDC2)HMM predict
325Phosphoserine(IKK)HMM predict
325Phosphoserine(CK2)HMM predict
325O-linkedHMM predict
326O-linkedHMM predict
327O-linkedHMM predict
328O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005522
  • Location:chr7 27099140-27102149
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 27102143 27102795 652 320
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 27094250 27094528 278 4752
FOXA1 MCF7GSE15244 27097108 27097935 827 1619
FoxA1 MCF7MACSdata 27097302 27097652 350 1664
RARA MCF7GSE15244 27096528 27099973 3445 890
TFAP2C MCF7GSE21234 27097206 27097704 498 1686
hScc1 BcellGSE12603 27094368 27094637 269 4638
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
USF1 HepG2E 27099973 27102143 2170 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-101 hsa-mir-101-1 1 16549775
hsa-miR-101 hsa-mir-101-2 9 16549775
hsa-miR-10a hsa-mir-10a 17 16549775
hsa-miR-10a* hsa-mir-10a 17 16549775
hsa-miR-10b hsa-mir-10b 2 16549775
hsa-miR-10b* hsa-mir-10b 2 16549775
hsa-miR-126 hsa-mir-126 9 16549775
hsa-miR-126* hsa-mir-126 9 16549775
hsa-miR-130a hsa-mir-130a 11 16549775
hsa-miR-130a* hsa-mir-130a 11 16549775
hsa-miR-135a hsa-mir-135a-1 3 16549775
hsa-miR-135a hsa-mir-135a-2 12 16549775
hsa-miR-135a* hsa-mir-135a-1 3 16549775
hsa-miR-135b hsa-mir-135b 1 16549775
hsa-miR-135b* hsa-mir-135b 1 16549775
hsa-miR-17 hsa-mir-17 13 16549775
hsa-miR-17* hsa-mir-17 13 16549775
hsa-miR-210 hsa-mir-210 11 19782034
hsa-miR-99a hsa-mir-99a 21 16549775
hsa-miR-99a* hsa-mir-99a 21 16549775
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
235 mRNA repression TRUE miR-10a HOXA1 in vitro reporter gene assay (Luciferase) 16549775
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000105991 n_a n_a n_a n_a "malignant tumour, carcinoma"
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
23776 EST chr7 26908505 26909186 26 mRNA HOXA1 chr7 26905855 26908834Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018