AutismKB 2.0

Annotation Detail for HOXB7


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Basic Information Top
Gene Symbol:HOXB7 ( HHO.C1,HOX2,HOX2C,Hox-2.3 )
Gene Full Name: homeobox B7
Band: 17q21.32
Quick LinksEntrez ID:3217; OMIM: 142962; Uniprot ID:HXB7_HUMAN; ENSEMBL ID: ENSG00000120087; HGNC ID: 5118
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
131Antp-type hexapeptide.
Location(AA) Modifications Resource
133Phosphoserine (CK2
191Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in ubiquitin).Swiss-Prot 53.0
193Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in ubiquitin).Swiss-Prot 53.0
204Phosphothreonine (CK2
Location(AA) Modification Resource
18O-linkedHMM predict
95N-linkedHMM predict
127SulfotyrosineHMM predict
143Phosphothreonine(PKC)HMM predict
163Phosphothreonine(PKC)HMM predict
196N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004502
  • Location:chr17 44039600-44043381
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 44043207 44043729 522 87
USF1 HepG2E 44043130 44043690 560 29
USF2 HepG2E 44043130 44043654 524 11
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Rb GrowingGSE19898 44042514 44042708 194 0
hScc1 BcellGSE12603 44042764 44043590 826 0
p130 QuiescentGSE19898 44042561 44043052 491 0
p130 SenescentGSE19898 44042632 44043063 431 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-196a hsa-mir-196a-1 17 20480203
hsa-miR-196a hsa-mir-196a-2 12 20480203
hsa-miR-196a* hsa-mir-196a-2 12 20480203
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018