AutismKB 2.0

Annotation Detail for APBB1


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Basic Information Top
Gene Symbol:APBB1 ( FE65,MGC:9072,RIR )
Gene Full Name: amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
Band: 11p15.4
Quick LinksEntrez ID:322; OMIM: 602709; Uniprot ID:APBB1_HUMAN; ENSEMBL ID: ENSG00000166313; HGNC ID: 581
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
546Phosphotyrosine (By similarity).
Location(AA) Modifications Resource
175Phosphoserine (MAPK1)Phospho.ELM 6.0
287Phosphoserine (MAPK1)Phospho.ELM 6.0
347Phosphoserine (MAPK1)Phospho.ELM 6.0
709Phosphothreonine (MAPK1)Phospho.ELM 6.0
Location(AA) Modification Resource
6Phosphoserine(IKK)HMM predict
8Phosphoserine(CK2)HMM predict
8Phosphoserine(ATM)HMM predict
8Phosphoserine(CK1)HMM predict
90N-linkedHMM predict
100Phosphoserine(ATM)HMM predict
111O-linkedHMM predict
174Phosphoserine(ATM)HMM predict
175Phosphoserine(MAPK)HMM predict
203Phosphoserine(CK1)HMM predict
203Phosphoserine(IKK)HMM predict
215Phosphoserine(PKG)HMM predict
218Phosphoserine(CK2)HMM predict
228Phosphoserine(ATM)HMM predict
231O-linkedHMM predict
234Phosphotyrosine(INSR)HMM predict
234Phosphotyrosine(SRC)HMM predict
236Phosphoserine(CDC2)HMM predict
287Phosphoserine(CDC2)HMM predict
289O-linkedHMM predict
289Phosphoserine(IKK)HMM predict
289Phosphoserine(ATM)HMM predict
293Phosphoserine(CDC2)HMM predict
322Phosphoserine(CK2)HMM predict
322Phosphoserine(CK1)HMM predict
347O-linkedHMM predict
347Phosphoserine(ATM)HMM predict
347Phosphoserine(CDK)HMM predict
347Phosphoserine(MAPK)HMM predict
347Phosphoserine(CDC2)HMM predict
571Phosphoserine(CK1)HMM predict
572Phosphoserine(CDC2)HMM predict
574Phosphoserine(CK1)HMM predict
666Phosphoserine(ATM)HMM predict
666Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001164
  • Location:chr11 6372930-6396875
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 6392546 6393103 557 0
ETS1 JurkatGSE17954 6380138 6381139 1001 0
H3K4me3 colorectalcancer 6396042 6396290 248 0
NRSF pAbJurkat 6388465 6389033 568 0
Oct1 H2O2-HelaGSE14283 6375772 6375831 59 0
Oct1 H2O2-HelaGSE14283 6389096 6389132 36 0
Oct1 HelaGSE14283 6389081 6389132 51 0
Oct1 HelaGSE14283 6393958 6393996 38 0
RARA MCF7GSE15244 6392332 6393176 844 0
RARG MCF7GSE15244 6388955 6389272 317 0
RARG MCF7GSE15244 6392592 6392974 382 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018