AutismKB 2.0

Annotation Detail for HOXD1


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Basic Information Top
Gene Symbol:HOXD1 ( HOX4,HOX4G,Hox-4.7 )
Gene Full Name: homeobox D1
Band: 2q31.1
Quick LinksEntrez ID:3231; OMIM: 142987; Uniprot ID:HXD1_HUMAN; ENSEMBL ID: ENSG00000128645; HGNC ID: 5132
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
209Antp-type hexapeptide.
Location(AA) Modifications Resource
Location(AA) Modification Resource
12Phosphoserine(CK1)HMM predict
62O-linkedHMM predict
62Phosphoserine(CDC2)HMM predict
64Phosphoserine(CDC2)HMM predict
64O-linkedHMM predict
64Phosphoserine(ATM)HMM predict
73O-linkedHMM predict
115Phosphotyrosine(Abl)HMM predict
182Phosphoserine(CDC2)HMM predict
182Phosphoserine(CDK)HMM predict
182O-linkedHMM predict
193Phosphoserine(CDC2)HMM predict
193Phosphoserine(IKK)HMM predict
215Phosphoserine(CAMK2)HMM predict
227Phosphoserine(CDC2)HMM predict
227Phosphoserine(CDK)HMM predict
255Phosphothreonine(PKC)HMM predict
269N-linkedHMM predict
307Phosphoserine(ATM)HMM predict
320Phosphoserine(IKK)HMM predict
320Phosphoserine(CDC2)HMM predict
324Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_024501
  • Location:chr2 176761552-176763880
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 176760673 176761157 484 638
H3ac HepG2E 176760493 176761301 808 656
USF1 HepG2E 176760455 176761381 926 635
USF2 HepG2E 176760455 176761301 846 675
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog hESGSE18292 176765315 176765876 561 1715
hScc1 BcellGSE12603 176773919 176774206 287 10182
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 176761337 176762151 814 0
H3ac HepG2E 176762409 176763538 1129 0
hScc1 BcellGSE12603 176761776 176762113 337 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-10a hsa-mir-10a 17 18167555
hsa-miR-10a* hsa-mir-10a 17 18167555
hsa-miR-10b hsa-mir-10b 2 18167555
hsa-miR-10b* hsa-mir-10b 2 18167555
hsa-miR-196a hsa-mir-196a-1 17 18167555
hsa-miR-196a hsa-mir-196a-2 12 18167555
hsa-miR-196a* hsa-mir-196a-2 12 18167555
hsa-miR-196b hsa-mir-196b 7 18167555
hsa-miR-615-3p hsa-mir-615 12 18167555
hsa-miR-615-5p hsa-mir-615 12 18167555
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
15321 mRNA HOXD1 chr2 176878813 176881142 145 EST chr2 176866690 176879193Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018