AutismKB 2.0

Annotation Detail for HRAS


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Basic Information Top
Gene Symbol:HRAS ( C-BAS/HAS,C-H-RAS,C-HA-RAS1,CTLO,H-RASIDX,HAMSV,HRAS1,K-RAS,N-RAS,RASH1 )
Gene Full Name: v-Ha-ras Harvey rat sarcoma viral oncogene homolog
Band: 11p15.5
Quick LinksEntrez ID:3265; OMIM: 190020; Uniprot ID:RASH_HUMAN; ENSEMBL ID: ENSG00000174775; HGNC ID: 5173
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1N-acetylmethionine; in GTPase HRas;
2N-acetylthreonine; in GTPase HRas, N-
40Effector region.
118S-nitrosocysteine.
186Cysteine methyl ester.
Location(AA) Modifications Resource
35PhosphothreoninePhospho.ELM 6.0
181S-palmitoyl cysteine.Swiss-Prot 53.0
184S-palmitoyl cysteine.Swiss-Prot 53.0
186Cysteine methyl ester.Swiss-Prot 53.0
186S-farnesyl cysteine.Swiss-Prot 53.0
Location(AA) Modification Resource
32SulfotyrosineHMM predict
40Phosphotyrosine(Jak)HMM predict
64Phosphotyrosine(Syk)HMM predict
64Phosphotyrosine(SRC)HMM predict
64Phosphotyrosine(INSR)HMM predict
85N-linkedHMM predict
86N-linkedHMM predict
181S-palmitoylHMM predict
181S-farnesylHMM predict
186S-farnesylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005343
  • Location:chr11 522242-525549
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 525370 525985 615 128
Fos K562GSE19551 525317 525988 671 103
PHF8 HeLaGSE20725 525256 526143 887 150
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 520232 521199 967 1527
H3ac HepG2E 520291 521158 867 1518
NRSF pAbJurkat 509400 510287 887 12399
hScc1 BcellGSE12603 520068 520291 223 2063
hScc1 G2GSE9613 520417 521562 1145 1253
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF pAbJurkat 522361 526252 3891 0
TFAP2C MCF7GSE21234 524538 524814 276 0
hScc1 BcellGSE12603 522813 523441 628 0
hScc1 BcellGSE12603 524671 525538 867 0
p63 keratinocytesGSE17611 524175 525313 1138 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-380 hsa-mir-380 14 20871609
hsa-miR-380* hsa-mir-380 14 20871609
hsa-miR-494 hsa-mir-494 14 20878133
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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