AutismKB 2.0

Annotation Detail for ERAS


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ERAS ( HRAS2,HRASP,MGC126691,MGC126693 )
Gene Full Name: ES cell expressed Ras
Band: Xp11.23
Quick LinksEntrez ID:3266; OMIM: 300437; Uniprot ID:RASE_HUMAN; ENSEMBL ID: ENSG00000187682; HGNC ID: 5174
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
78Effector region (By similarity).
230Cysteine methyl ester (By similarity).
Location(AA) Modifications Resource
226S-palmitoyl cysteine (By similarity).Swiss-Prot 53.0
228S-palmitoyl cysteine (By similarity).Swiss-Prot 53.0
230Cysteine methyl ester (By similarity).Swiss-Prot 53.0
230S-farnesyl cysteine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
126Phosphoserine(CK1)HMM predict
193Phosphoserine(CK1)HMM predict
228S-farnesylHMM predict
229GlycineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_181532
  • Location:chrX 48572226-48573491
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 48569587 48571004 1417 1931
hScc1 G2GSE9613 48569787 48571111 1324 1778
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 48572291 48572438 147 0
CTCF G2GSE9613 48572946 48573126 180 0
hScc1 G2GSE9613 48572196 48573126 930 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018