Annotation Detail for PRMT2

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Basic Information Top

Gene Symbol:	PRMT2 ( HRMT1L1,MGC111373 )
Gene Full Name:	protein arginine methyltransferase 2
Band:	21q22.3
Quick Links	Entrez ID:3275; OMIM: 601961; Uniprot ID:ANM2_HUMAN; ENSEMBL ID: ENSG00000160310; HGNC ID: 5186
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:0 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:5 results

No data

Location(AA)	Modification	Resource
12	Phosphoserine(PKG)	HMM predict
12	Phosphoserine(ATM)	HMM predict
406	Phosphoserine(PKB)	HMM predict
416	Arginine	HMM predict
421	Phosphoserine(ATM)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_001535
Location:chr21 46879954-46909289
strand:+

Upstream the gene:4 results
Downstream the gene:2 results
Inside the gene:13 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
PHF8	Hs68plusFBS	GSE20725	46879044	46880684	1640	91
p130	Quiescent	GSE19898	46879494	46879863	369	276
p130	Senescent	GSE19898	46879293	46879923	630	347
p130	shRbSenescent	GSE19898	46879274	46879658	384	489

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CBP	T0-glioblastoma	GSE21026	46926704	46927258	554	17692
RARA	MCF7	GSE15244	46927205	46927625	420	18126

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	46884206	46884574	368	0
CTCF	CD4	GSE12889	46905600	46905763	163	0
CTCF	CD4	SISSRdata	46884206	46884574	368	0
CTCF	CD4	SISSRdata	46905600	46905763	163	0
CTCF	Jurkat	GSE12889	46905524	46905808	284	0
FOXA1	MCF7	GSE15244	46887887	46888822	935	0
H3K4me3	colorectal	cancer	46880660	46881009	349	0
PHF8	293T	GSE20725	46879214	46880800	1586	0
PHF8	HeLa	GSE20725	46879252	46880756	1504	0
TFAP2C	MCF7	GSE21234	46907407	46907864	457	0
hScc1	Bcell	GSE12603	46880219	46880546	327	0
hScc1	Bcell	GSE12603	46905677	46906771	1094	0
p130	shRbQuiescent	GSE19898	46879754	46880397	643	0

Validated miRNA targets

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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