AutismKB 2.0

Annotation Detail for HSPA1A


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:HSPA1A ( FLJ54303,FLJ54370,FLJ54392,FLJ54408,FLJ75127,HSP70-1,HSP70-1A,HSP70I,HSP72,HSPA1,HSPA1B )
Gene Full Name: heat shock 70kDa protein 1A
Band: 6p21.33
Quick LinksEntrez ID:3303; OMIM: 140550; Uniprot ID:HSP71_HUMAN; ENSEMBL ID: ENSG00000204389; HGNC ID: 5232
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
41Phosphotyrosine.
106Phosphoserine.
107Phosphotyrosine.
108N6-acetyllysine.
246N6-acetyllysine.
348N6-acetyllysine.
611Phosphotyrosine.
631Phosphoserine.
Location(AA) Modifications Resource
525PhosphotyrosinePhospho.ELM 6.0
631Phosphoserine.Swiss-Prot 53.0
631PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
35N-linkedHMM predict
158Phosphothreonine(PKC)HMM predict
158Phosphothreonine(PKA)HMM predict
273Phosphothreonine(PKA)HMM predict
273Phosphothreonine(PKC)HMM predict
275Phosphoserine(CK1)HMM predict
275Phosphoserine(PKG)HMM predict
275Phosphoserine(IKK)HMM predict
360N-linkedHMM predict
364N-linkedHMM predict
400Phosphoserine(MAPK)HMM predict
417N-linkedHMM predict
425Phosphothreonine(PKA)HMM predict
450Phosphothreonine(PKC)HMM predict
487N-linkedHMM predict
511Phosphoserine(PKG)HMM predict
525Phosphotyrosine(Syk)HMM predict
537Phosphoserine(PKG)HMM predict
627ProlineHMM predict
628O-linkedHMM predict
631Phosphoserine(IKK)HMM predict
633Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005345
  • Location:chr6 31891315-31893695
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Rb SenescentGSE19898 31891130 31891441 311 30
TFAP2C MCF7GSE21234 31890946 31891571 625 57
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 31897391 31898102 711 4051
H3K4me3 colorectalcancer 31894191 31894553 362 677
H3ac HepG2E 31894191 31894755 564 778
H3ac HepG2E 31895572 31895895 323 2038
H3ac HepG2E 31900343 31900589 246 6771
Myc hESGSE17917 31897406 31897920 514 3968
PHF8 293TGSE20725 31897143 31898160 1017 3956
TAF HelaGSE8489 31894191 31894481 290 641
TAF k562GSE8489 31894191 31894755 564 778
TAF k562GSE8489 31895572 31896089 517 2135
TAF k562GSE8489 31896438 31897082 644 3065
TAF k562GSE8489 31897965 31898675 710 4625
TAF k562GSE8489 31899032 31899316 284 5479
TAF k562GSE8489 31900972 31901693 721 7637
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 31890580 31892350 1770 0
CTCF G2GSE9613 31893070 31893221 151 0
H3K4me3 colorectalcancer 31891578 31893857 2279 0
H3ac HepG2E 31891705 31893857 2152 0
PHF8 HeLaGSE20725 31891223 31891681 458 0
Pol2 GM12878GSE19551 31891086 31891571 485 0
RARA MCF7GSE15244 31892674 31893838 1164 0
TAF k562GSE8489 31892775 31893857 1082 0
hScc1 BcellGSE12603 31891223 31892997 1774 0
hScc1 CdLSGSE12603 31892881 31893838 957 0
p130 SenescentGSE19898 31891236 31891584 348 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-15a hsa-mir-15a 13 18362358
hsa-miR-15a hsa-mir-15a 13 18362358
hsa-miR-15a* hsa-mir-15a 13 18362358
hsa-miR-15a* hsa-mir-15a 13 18362358
hsa-miR-16 hsa-mir-16-1 13 18362358
hsa-miR-16 hsa-mir-16-2 3 18362358
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-16 hsa-mir-16-1 13 18362358
hsa-miR-16 hsa-mir-16-2 3 18362358
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-16-1* hsa-mir-16-1 13 18362358
hsa-miR-16-1* hsa-mir-16-1 13 18362358
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
22433 mRNA HSPA1A chr6 31891315 31893698 546 EST chr6 31892325 31893131Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved