AutismKB 2.0

Annotation Detail for HSPA6


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Basic Information Top
Gene Symbol:HSPA6 ( - )
Gene Full Name: heat shock 70kDa protein 6 (HSP70B')
Band: 1q23.3
Quick LinksEntrez ID:3310; OMIM: 140555; Uniprot ID:HSP76_HUMAN; ENSEMBL ID: ENSG00000173110; HGNC ID: 5239
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
321N6-acetyllysine.
502N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
37N-linkedHMM predict
117Phosphotyrosine(EGFR)HMM predict
160Phosphothreonine(PKC)HMM predict
160Phosphothreonine(PKA)HMM predict
275Phosphothreonine(PKC)HMM predict
275Phosphothreonine(PKA)HMM predict
277Phosphoserine(IKK)HMM predict
277Phosphoserine(CK1)HMM predict
277Phosphoserine(PKG)HMM predict
362N-linkedHMM predict
366N-linkedHMM predict
402Phosphoserine(MAPK)HMM predict
419N-linkedHMM predict
432O-linkedHMM predict
452Phosphothreonine(PKC)HMM predict
513Phosphoserine(PKG)HMM predict
527Phosphotyrosine(Syk)HMM predict
594Phosphotyrosine(Syk)HMM predict
622O-linkedHMM predict
625GlycineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002155
  • Location:chr1 159760659-159763308
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 159760044 159760593 549 341
Myc K562GSE19551 159760126 159760412 286 391
PHF8 Hs68minusFBSGSE20725 159760141 159760754 613 212
PHF8 Hs68plusFBSGSE20725 159760070 159760900 830 175
Pol3 GM12878GSE19551 159759943 159760565 622 406
Pol3 K562GSE19551 159759872 159760779 907 334
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 159766473 159768160 1687 4008
Oct1 HelaGSE14283 159765569 159765606 37 2279
PHF8 Hs68minusFBSGSE20725 159767209 159767972 763 4282
PHF8 Hs68plusFBSGSE20725 159766337 159767293 956 3507
Pol3 GM12878GSE19551 159766482 159766984 502 3425
Pol3 GM12878GSE19551 159767157 159767963 806 4252
Rb SenescentGSE19898 159766736 159766926 190 3523
TAF k562GSE8489 159766320 159767067 747 3385
TAF k562GSE8489 159769814 159770516 702 6857
hScc1 CdLSGSE12603 159766948 159767891 943 4111
p130 QuiescentGSE19898 159767171 159767350 179 3952
p130 SenescentGSE19898 159767561 159767709 148 4327
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 159760698 159761410 712 0
hScc1 BcellGSE12603 159760563 159761574 1011 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018