AutismKB 2.0

Annotation Detail for HSP90AA1


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Basic Information Top
Gene Symbol:HSP90AA1 ( FLJ31884,HSP86,HSP89A,HSP90A,HSP90N,HSPC1,HSPCA,HSPCAL1,HSPCAL4,HSPN,Hsp89,Hsp90,LAP2 )
Gene Full Name: heat shock protein 90kDa alpha (cytosolic), class A member 1
Band: 14q32.31
Quick LinksEntrez ID:3320; OMIM: 140571; Uniprot ID:HS90A_HUMAN; ENSEMBL ID: ENSG00000080824; HGNC ID: 5253
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
5Phosphothreonine; by PRKDC.
7Phosphothreonine; by PRKDC.
224N6-acetyllysine.
231Phosphoserine.
252Phosphoserine.
263Phosphoserine.
313Phosphotyrosine (By similarity).
399Phosphoserine.
410N6-acetyllysine.
443N6-acetyllysine.
458N6-acetyllysine.
489N6-acetyllysine.
492Phosphotyrosine (By similarity).
576N6-acetyllysine.
585N6-acetyllysine.
598S-nitrosocysteine.
732TPR repeat-binding.
Location(AA) Modifications Resource
4PhosphothreoninePhospho.ELM 6.0
5Phosphothreonine (by PRKDC).Swiss-Prot 53.0
6Phosphothreonine (DNA-PK)Phospho.ELM 6.0
7Phosphothreonine (by PRKDC).Swiss-Prot 53.0
230Phosphoserine (CK2
231Phosphoserine.Swiss-Prot 53.0
252Phosphoserine.Swiss-Prot 53.0
262Phosphoserine (CK2
263Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
51N-linkedHMM predict
160SulfotyrosineHMM predict
160Phosphotyrosine(Syk)HMM predict
197Phosphotyrosine(Syk)HMM predict
231PhosphoserineHMM predict
231Phosphoserine(CK2)HMM predict
263Phosphoserine(CK2)HMM predict
263Phosphoserine(CK1)HMM predict
263PhosphoserineHMM predict
284Phosphotyrosine(Jak)HMM predict
291N-linkedHMM predict
309Phosphotyrosine(EGFR)HMM predict
309SulfotyrosineHMM predict
309Phosphotyrosine(INSR)HMM predict
309Phosphotyrosine(SRC)HMM predict
434Phosphotyrosine(EGFR)HMM predict
434Phosphotyrosine(Syk)HMM predict
434Phosphotyrosine(INSR)HMM predict
438Phosphotyrosine(Syk)HMM predict
597S-palmitoylHMM predict
598S-palmitoylHMM predict
622N-linkedHMM predict
708O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001017963
  • Location:chr14 101617138-101675775
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 101613572 101613746 174 3480
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 101632695 101633063 368 0
CTCF CD4SISSRdata 101632695 101633063 368 0
CTCF G2GSE9613 101622836 101623606 770 0
CTCF G2GSE9613 101630593 101631040 447 0
CTCF G2GSE9613 101632465 101632827 362 0
Fos K562GSE19551 101631492 101632173 681 0
FoxA1 MCF7MACSdata 101661526 101661764 238 0
NFkBII GM15510GSE19485 101622191 101624111 1920 0
Oct1 H2O2-HelaGSE14283 101658804 101658842 38 0
Oct1 HelaGSE14283 101658804 101658833 29 0
P300 T30-glioblastomaGSE21026 101622622 101624078 1456 0
PHF8 HeLaGSE20725 101622441 101624172 1731 0
Pol2 GM12878GSE19551 101622408 101623979 1571 0
RARA MCF7GSE15244 101633425 101634004 579 0
RARG MCF7GSE15244 101632391 101633002 611 0
RARG MCF7GSE15244 101633425 101634210 785 0
TFAP2C MCF7GSE21234 101633462 101634303 841 0
hScc1 BcellGSE12603 101622836 101623536 700 0
hScc1 BcellGSE12603 101631886 101632968 1082 0
hScc1 CdLSGSE12603 101632465 101633056 591 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
8400 EST chr14 101617144 101617621 466 mRNA HSPCA chr14 101617144 101623135Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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