Annotation Detail for DNAJB1

View Evidences	View Variants	View Annotations

Basic Information Top

Gene Symbol:	DNAJB1 ( HSPF1,Hdj1,Hsp40,RSPH16B,Sis1 )
Gene Full Name:	DnaJ (Hsp40) homolog, subfamily B, member 1
Band:	19p13.12
Quick Links	Entrez ID:3337; OMIM: 604572; Uniprot ID:DNJB1_HUMAN; ENSEMBL ID: ENSG00000132002; HGNC ID: 5270
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
44	N6-acetyllysine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	14490087	14490397	310	42
hScc1	Bcell	GSE12603	14491212	14491399	187	1105
p130	Senescent	GSE19898	14490291	14490623	332	257
p130	shRbSenescent	GSE19898	14490416	14490737	321	376

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	14477296	14477544	248	9162
CTCF	CD4	SISSRdata	14477296	14477544	248	9162
CTCF	Hela	GSE12889	14477297	14477517	220	9175
CTCF	Jurkat	GSE12889	14477292	14477586	294	9143
CTCF	G2	GSE9613	14477267	14477951	684	8973
FOXA1	MCF7	GSE15244	14479554	14479918	364	6846
RARA	MCF7	GSE15244	14479461	14479918	457	6892
TFAP2C	MCF7	GSE21234	14477125	14478429	1304	8805
TFAP2C	MCF7	GSE21234	14479474	14480187	713	6751
hScc1	Bcell	GSE12603	14477267	14477909	642	8994
p130	Senescent	GSE19898	14477423	14477941	518	8900
p130	shRbQuiescent	GSE19898	14477473	14478010	537	8840
p130	shRbSenescent	GSE19898	14477584	14477965	381	8807

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
H3K4me3	colorectal	cancer	14487775	14488502	727
H3ac	HepG2	E	14487144	14488470	1326
PHF8	293T	GSE20725	14489459	14490840	1381
PHF8	HeLa	GSE20725	14489017	14491173	2156
PHF8	Hs68minusFBS	GSE20725	14489472	14490682	1210
PHF8	Hs68plusFBS	GSE20725	14489101	14490749	1648
hScc1	Bcell	GSE12603	14489228	14490469	1241
p130	shRbQuiescent	GSE19898	14489868	14490282	414

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
953	Unknown	pSILAC	miR-155	DNAJB1	down 50-25%	18668040
1152	Unknown	pSILAC	miR-1	DNAJB1	down 50-25%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000132002		n_a	n_a	n_a	"squamous cell, epithelium, lymphocyte, leukocyte, macrophage, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, non-Hodgkin's, sarcoma"
ENSG00000132002		n_a	n_a	n_a	"squamous cell, epithelium, lymphocyte, leukocyte, macrophage, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, non-Hodgkin's, sarcoma"

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
12801	EST		chr19	14488896	14535550	1305	mRNA	DNAJB1	chr19	14486581	14490201	Non-exonic Bidirectional (NOB) pairs

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018