AutismKB 2.0

Annotation Detail for HTR1A


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Basic Information Top
Gene Symbol:HTR1A ( 5-HT1A,5HT1a,ADRB2RL1,ADRBRL1 )
Gene Full Name: 5-hydroxytryptamine (serotonin) receptor 1A
Band: 5q12.3
Quick LinksEntrez ID:3350; OMIM: 109760; Uniprot ID:5HT1A_HUMAN; ENSEMBL ID: ENSG00000178394; HGNC ID: 5286
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
10N-linked (GlcNAc...) (Potential).
11N-linked (GlcNAc...) (Potential).
24N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
10N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
11N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
24N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
334Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in ubiquitin).Swiss-Prot 53.0
Location(AA) Modification Resource
10N-linkedHMM predict
11N-linkedHMM predict
12O-linkedHMM predict
13O-linkedHMM predict
14Phosphoserine(CDC2)HMM predict
24N-linkedHMM predict
149Phosphothreonine(MAPK)HMM predict
229Phosphothreonine(PKC)HMM predict
245Phosphoserine(CDC2)HMM predict
245O-linkedHMM predict
309O-linkedHMM predict
314O-linkedHMM predict
314O-linkedHMM predict
343Phosphothreonine(PKC)HMM predict
371S-palmitoylHMM predict
421ArginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000524
  • Location:chr5 63292034-63293301
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF JurkatGSE13047 63291996 63295202 3206 298
NRSF mAbJurkat 63290268 63296337 6069 1
NRSF-mono JurkatQuESTdata 63293947 63295201 1254 1273
NRSF pAbJurkat 63293540 63295052 1512 995
NRSF-poly JurkatQuESTdata 63293849 63295110 1261 1178
P300 T30-glioblastomaGSE21026 63294765 63295087 322 1625
hScc1 BcellGSE12603 63293659 63293942 283 499
hScc1 CdLSGSE12603 63294628 63295088 460 1557
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF mAbJurkat 63286631 63288830 2199 4304
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 63292039 63292503 464 0
CTCF G2GSE9613 63292927 63293286 359 0
hScc1 BcellGSE12603 63292998 63293395 397 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018