AutismKB 2.0

Annotation Detail for HTR2A


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Basic Information Top
Gene Symbol:HTR2A ( 5-HT2A,HTR2 )
Gene Full Name: 5-hydroxytryptamine (serotonin) receptor 2A
Band: 13q14.2
Quick LinksEntrez ID:3356; OMIM: 182135; Uniprot ID:5HT2A_HUMAN; ENSEMBL ID: ENSG00000102468; HGNC ID: 5293
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
8N-linked (GlcNAc...) (Potential).
38N-linked (GlcNAc...) (Potential).
44N-linked (GlcNAc...) (Potential).
51N-linked (GlcNAc...) (Potential).
54N-linked (GlcNAc...) (Potential).
471PDZ-binding.
Location(AA) Modifications Resource
8N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
38N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
44N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
51N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
54N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
8N-linkedHMM predict
10Phosphoserine(IKK)HMM predict
10Phosphoserine(CK1)HMM predict
10O-linkedHMM predict
38N-linkedHMM predict
44N-linkedHMM predict
51N-linkedHMM predict
54N-linkedHMM predict
60S-palmitoylHMM predict
67Phosphoserine(CK1)HMM predict
107N-linkedHMM predict
110N-linkedHMM predict
111Phosphotyrosine(INSR)HMM predict
174Phosphotyrosine(Jak)HMM predict
287Phosphoserine(IKK)HMM predict
290Phosphoserine(CK1)HMM predict
384N-linkedHMM predict
422Phosphoserine(ATM)HMM predict
457Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000621
  • Location:chr13 46305513-46368175
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 CdLSGSE12603 46377268 46377932 664 9425
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 46303864 46303988 124 1588
CTCF CD4SISSRdata 46303864 46303988 124 1588
hScc1 BcellGSE12603 46303704 46304084 380 1620
hScc1 CdLSGSE12603 46303635 46304327 692 1533
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 46325735 46325903 168 0
CTCF G2GSE9613 46362501 46363104 603 0
CTCF G2GSE9613 46366030 46366574 544 0
Oct1 HelaGSE14283 46350218 46350250 32 0
TFAP2C MCF7GSE21234 46338238 46338871 633 0
hScc1 BcellGSE12603 46366030 46366831 801 0
hScc1 CdLSGSE12603 46365813 46366801 988 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
7174 EST chr13 46324278 46328511 4233 mRNA HTR2A chr13 46305513 46368176 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018