AutismKB 2.0

Annotation Detail for HTR2C


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Basic Information Top
Gene Symbol:HTR2C ( 5-HT2C,5-HTR2C,HTR1C )
Gene Full Name: 5-hydroxytryptamine (serotonin) receptor 2C
Band: Xq23
Quick LinksEntrez ID:3358; OMIM: 312861; Uniprot ID:5HT2C_HUMAN; ENSEMBL ID: ENSG00000147246; HGNC ID: 5295
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
39N-linked (GlcNAc...) (Probable).
458PDZ-binding.
Location(AA) Modifications Resource
39N-linked (GlcNAc...) (Probable).Swiss-Prot 53.0
456PhosphoserinePhospho.ELM 6.0
457PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
28Phosphoserine(CDC2)HMM predict
39N-linkedHMM predict
86N-linkedHMM predict
89N-linkedHMM predict
90Phosphotyrosine(INSR)HMM predict
203N-linkedHMM predict
204N-linkedHMM predict
210N-linkedHMM predict
266S-palmitoylHMM predict
267S-palmitoylHMM predict
310Phosphoserine(PKG)HMM predict
375Phosphotyrosine(EGFR)HMM predict
404O-linkedHMM predict
446N-linkedHMM predict
452O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000868
  • Location:chrX 113724806-114050879
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 113723912 113724179 267 761
H3K27me3 colorectalcancer 113723025 113724574 1549 1007
hScc1 G2GSE9613 113723830 113724105 275 839
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 113882189 113882411 222 0
CBP T30-glioblastomaGSE21026 113881880 113882383 503 0
CBP T30-glioblastomaGSE21026 113981771 113982418 647 0
CTCF CD4GSE12889 113751841 113752128 287 0
CTCF CD4SISSRdata 113751841 113752128 287 0
CTCF G2GSE9613 113751877 113752093 216 0
Nanog ESGSE20650 113742242 113742413 171 0
Nanog ESGSE20650 113747582 113747997 415 0
Nanog ESGSE20650 113976872 113976974 102 0
Oct1 H2O2-HelaGSE14283 113737823 113737854 31 0
Oct1 H2O2-HelaGSE14283 113860734 113860764 30 0
Oct1 H2O2-HelaGSE14283 113893931 113893969 38 0
Oct1 H2O2-HelaGSE14283 113899905 113899937 32 0
Oct1 H2O2-HelaGSE14283 113929963 113929993 30 0
Oct1 HelaGSE14283 113737822 113737854 32 0
Oct1 HelaGSE14283 113860734 113860764 30 0
Oct1 HelaGSE14283 113893934 113893969 35 0
Oct1 HelaGSE14283 113899906 113899936 30 0
P300 T30-glioblastomaGSE21026 113939491 113940317 826 0
TAF HelaGSE8489 113997848 113998130 282 0
TFAP2C MCF7GSE21234 113915514 113915844 330 0
hScc1 G2GSE9613 113725234 113725400 166 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-138 hsa-mir-138-2 16 21168126
hsa-miR-138 hsa-mir-138-1 3 21168126
hsa-miR-138-2* hsa-mir-138-2 16 21168126
hsa-miR-148a hsa-mir-148a 7 21168126
hsa-miR-148a* hsa-mir-148a 7 21168126
hsa-miR-22 hsa-mir-22 17 21168126
hsa-miR-22* hsa-mir-22 17 21168126
hsa-miR-339-3p hsa-mir-339 7 21168126
hsa-miR-339-5p hsa-mir-339 7 21168126
hsa-miR-448 hsa-mir-448 X 20719859
hsa-miR-488 hsa-mir-488 1 21168126
hsa-miR-488* hsa-mir-488 1 21168126
hsa-miR-491-3p hsa-mir-491 9 21168126
hsa-miR-491-5p hsa-mir-491 9 21168126
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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