AutismKB 2.0

Annotation Detail for TNC


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Basic Information Top
Gene Symbol:TNC ( 150-225,GMEM,GP,HXB,JI,MGC167029,TN,TN-C )
Gene Full Name: tenascin C
Band: 9q33.1
Quick LinksEntrez ID:3371; OMIM: 187380; Uniprot ID:TENA_HUMAN; ENSEMBL ID: ENSG00000041982; HGNC ID: 5318
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
38N-linked (GlcNAc...) (Potential).
70Phosphoserine (By similarity).
72Phosphoserine (By similarity).
166N-linked (GlcNAc...) (Potential).
184N-linked (GlcNAc...).
327N-linked (GlcNAc...) (Potential).
788N-linked (GlcNAc...) (Potential).
1018N-linked (GlcNAc...).
1034N-linked (GlcNAc...).
1079N-linked (GlcNAc...).
1093N-linked (GlcNAc...).
1119N-linked (GlcNAc...) (Potential).
1184N-linked (GlcNAc...).
1210N-linked (GlcNAc...) (Potential).
1261N-linked (GlcNAc...).
1275N-linked (GlcNAc...).
1301N-linked (GlcNAc...).
1366N-linked (GlcNAc...).
1392N-linked (GlcNAc...) (Potential).
1445N-linked (GlcNAc...) (Potential).
1455N-linked (GlcNAc...) (Potential).
1485N-linked (GlcNAc...).
1534N-linked (GlcNAc...) (Potential).
1809N-linked (GlcNAc...).
2162N-linked (GlcNAc...).
Location(AA) Modifications Resource
38N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
72Phosphoserine (By similarity).Swiss-Prot 53.0
166N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
184N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
327N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
788N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1018N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1034N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1079N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1093N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1119N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1184N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1210N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1261N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1275N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1301N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1366N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1392N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1445N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1455N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1485N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1534N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1809N-linked (GlcNAc...).Swiss-Prot 53.0
2162N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
38N-linkedHMM predict
84O-linkedHMM predict
166N-linkedHMM predict
172S-palmitoylHMM predict
176S-palmitoylHMM predict
184N-linkedHMM predict
217Phosphoserine(ATM)HMM predict
270S-palmitoylHMM predict
327N-linkedHMM predict
346S-palmitoylHMM predict
429Phosphotyrosine(INSR)HMM predict
463Phosphotyrosine(INSR)HMM predict
491Phosphotyrosine(INSR)HMM predict
705O-linkedHMM predict
788N-linkedHMM predict
789N-linkedHMM predict
869Phosphotyrosine(Syk)HMM predict
869Phosphotyrosine(Jak)HMM predict
903Phosphoserine(PKG)HMM predict
903Phosphoserine(IKK)HMM predict
943Phosphoserine(ATM)HMM predict
947O-linkedHMM predict
974Phosphoserine(IKK)HMM predict
1018N-linkedHMM predict
1034N-linkedHMM predict
1062Phosphoserine(PKB)HMM predict
1062Phosphoserine(PKA)HMM predict
1070Phosphoserine(PKG)HMM predict
1070O-linkedHMM predict
1079N-linkedHMM predict
1093N-linkedHMM predict
1101Phosphotyrosine(EGFR)HMM predict
1119N-linkedHMM predict
1153Phosphothreonine(CDK)HMM predict
1165Phosphothreonine(CDK)HMM predict
1184N-linkedHMM predict
1192Phosphotyrosine(SRC)HMM predict
1210N-linkedHMM predict
1245Phosphothreonine(MAPK)HMM predict
1261N-linkedHMM predict
1275N-linkedHMM predict
1301N-linkedHMM predict
1307Phosphoserine(IKK)HMM predict
1322Phosphotyrosine(Abl)HMM predict
1366N-linkedHMM predict
1372N-linkedHMM predict
1374Phosphotyrosine(EGFR)HMM predict
1392N-linkedHMM predict
1445N-linkedHMM predict
1450Phosphothreonine(MAPK)HMM predict
1487Phosphoserine(CK2)HMM predict
1496O-linkedHMM predict
1519O-linkedHMM predict
1523O-linkedHMM predict
1525O-linkedHMM predict
1534N-linkedHMM predict
1595Phosphotyrosine(INSR)HMM predict
1699Phosphoserine(PKG)HMM predict
1701Phosphothreonine(PKC)HMM predict
1703O-linkedHMM predict
1708O-linkedHMM predict
1727Phosphothreonine(PKC)HMM predict
1729Phosphoserine(IKK)HMM predict
1792O-linkedHMM predict
1794Phosphoserine(IKK)HMM predict
1809N-linkedHMM predict
1825Phosphothreonine(PKC)HMM predict
1828O-linkedHMM predict
1878O-linkedHMM predict
1900O-linkedHMM predict
1946Phosphoserine(ATM)HMM predict
2123Phosphoserine(PKB)HMM predict
2162N-linkedHMM predict
2164Phosphoserine(ATM)HMM predict
2168N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002160
  • Location:chr9 116822633-116920259
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 116922427 116922878 451 2393
P300 T30-glioblastomaGSE21026 116928987 116929752 765 9110
TFAP2C MCF7GSE21234 116920900 116921331 431 856
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 116816114 116816509 395 6322
CTCF CD4SISSRdata 116816114 116816509 395 6322
Oct1 HelaGSE14283 116821287 116821324 37 1328
P300 T30-glioblastomaGSE21026 116810436 116811348 912 11742
STAT1 HeLaGSE12783 116812356 116813639 1283 9636
hScc1 BcellGSE12603 116815537 116816651 1114 6540
hScc1 CdLSGSE12603 116815744 116816651 907 6436
hScc1 G2GSE9613 116815605 116816578 973 6542
p130 QuiescentGSE19898 116821122 116821213 91 1466
p130 shRbQuiescentGSE19898 116820654 116821004 350 1805
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 116919819 116920246 427 0
Nanog hESGSE18292 116827273 116827578 305 0
Nanog hESGSE18292 116852224 116852442 218 0
Oct1 HelaGSE14283 116829907 116829946 39 0
Oct1 HelaGSE14283 116895918 116895951 33 0
Oct1 HelaGSE14283 116898987 116899054 67 0
Rb shRbSenescenceGSE19898 116889177 116889392 215 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-10b hsa-mir-10b 2 18373886
hsa-miR-10b* hsa-mir-10b 2 18373886
hsa-miR-126 hsa-mir-126 9 18373886
hsa-miR-126* hsa-mir-126 9 18373886
hsa-miR-206 hsa-mir-206 6 18373886
hsa-miR-335 hsa-mir-335 7 18373886
hsa-miR-335* hsa-mir-335 7 18373886
hsa-miR-373 hsa-mir-373 19 18373886
hsa-miR-373* hsa-mir-373 19 18373886
hsa-miR-520c-3p hsa-mir-520c 19 18373886
hsa-miR-520c-5p hsa-mir-520c 19 18373886
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
26958 EST chr9 114800273 114910921 127 mRNA TNC chr9 114862366 114959993Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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