AutismKB 2.0

Annotation Detail for APOB


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Basic Information Top
Gene Symbol:APOB ( FLDB,LDLCQ4 )
Gene Full Name: apolipoprotein B (including Ag(x) antigen)
Band: 2p24.1
Quick LinksEntrez ID:338; OMIM: 107730; Uniprot ID:APOB_HUMAN; ENSEMBL ID: ENSG00000084674; HGNC ID: 603
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
34N-linked (GlcNAc...) (Potential).
185N-linked (GlcNAc...).
928Phosphoserine.
983N-linked (GlcNAc...) (Potential).
1368N-linked (GlcNAc...) (Potential).
1377N-linked (GlcNAc...) (Potential).
1523N-linked (GlcNAc...).
2004N6-acetyllysine.
2239N-linked (GlcNAc...).
2560N-linked (GlcNAc...) (Potential).
2779N-linked (GlcNAc...).
2982N-linked (GlcNAc...).
3101N-linked (GlcNAc...).
3224N-linked (GlcNAc...).
3336N-linked (GlcNAc...) (Potential).
3358N-linked (GlcNAc...).
3411N-linked (GlcNAc...).
3465N-linked (GlcNAc...).
3895N-linked (GlcNAc...).
4237N-linked (GlcNAc...) (Potential).
4431N-linked (GlcNAc...) (Potential).
4507Phosphoserine.
Location(AA) Modifications Resource
34N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
185N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
983N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1112S-palmitoyl cysteine.Swiss-Prot 53.0
1368N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1377N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1523N-linked (GlcNAc...).Swiss-Prot 53.0
2239N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2560N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2779N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2982N-linked (GlcNAc...).Swiss-Prot 53.0
3101N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3224N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3336N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3358N-linked (GlcNAc...).Swiss-Prot 53.0
3411N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3465N-linked (GlcNAc...).Swiss-Prot 53.0
3895N-linked (GlcNAc...).Swiss-Prot 53.0
4237N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
4431N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
152Phosphotyrosine(INSR)HMM predict
185N-linkedHMM predict
244PhosphoserineHMM predict
312O-linkedHMM predict
315Phosphoserine(IKK)HMM predict
317PhosphoserineHMM predict
317Phosphoserine(CDC2)HMM predict
441Phosphothreonine(PKA)HMM predict
456N-linkedHMM predict
484Phosphotyrosine(INSR)HMM predict
570PhosphoserineHMM predict
570Phosphoserine(ATM)HMM predict
622Phosphoserine(ATM)HMM predict
647O-linkedHMM predict
666Phosphotyrosine(Syk)HMM predict
666Phosphotyrosine(Jak)HMM predict
829SulfotyrosineHMM predict
928Phosphoserine(CDC2)HMM predict
964Phosphoserine(IKK)HMM predict
981Phosphotyrosine(INSR)HMM predict
982Phosphoserine(IKK)HMM predict
982O-linkedHMM predict
983N-linkedHMM predict
986O-linkedHMM predict
987O-linkedHMM predict
1015Phosphoserine(IKK)HMM predict
1157Phosphotyrosine(Abl)HMM predict
1159O-linkedHMM predict
1190Phosphothreonine(PKA)HMM predict
1190Phosphothreonine(PKC)HMM predict
1363Phosphotyrosine(SRC)HMM predict
1374Phosphoserine(IKK)HMM predict
1377N-linkedHMM predict
1545O-linkedHMM predict
1602Phosphotyrosine(Syk)HMM predict
1606SulfotyrosineHMM predict
1644Phosphothreonine(PKA)HMM predict
1678Phosphoserine(ATM)HMM predict
1792Phosphoserine(IKK)HMM predict
1973Phosphothreonine(MAPK)HMM predict
1992SulfotyrosineHMM predict
2001Phosphothreonine(PKC)HMM predict
2022Phosphoserine(CDC2)HMM predict
2136Phosphoserine(PKG)HMM predict
2239N-linkedHMM predict
2243Phosphoserine(CK2)HMM predict
2432Phosphotyrosine(EGFR)HMM predict
2560N-linkedHMM predict
2779N-linkedHMM predict
2785N-linkedHMM predict
2856Phosphothreonine(PKC)HMM predict
2982N-linkedHMM predict
2990Phosphoserine(ATM)HMM predict
2994Phosphoserine(ATM)HMM predict
3079Phosphoserine(MAPK)HMM predict
3079Phosphoserine(CDC2)HMM predict
3079Phosphoserine(CDK)HMM predict
3224N-linkedHMM predict
3251Phosphotyrosine(Jak)HMM predict
3336N-linkedHMM predict
3368Phosphoserine(CK1)HMM predict
3369Phosphoserine(CK1)HMM predict
3372Phosphoserine(CK1)HMM predict
3411N-linkedHMM predict
3428Phosphothreonine(PKC)HMM predict
3453Phosphothreonine(PKC)HMM predict
3482Phosphoserine(CK1)HMM predict
3491O-linkedHMM predict
3510Phosphoserine(CK1)HMM predict
3605Phosphoserine(ATM)HMM predict
3801Phosphoserine(ATM)HMM predict
3801Phosphoserine(CK2)HMM predict
3823Phosphoserine(ATM)HMM predict
3895N-linkedHMM predict
3908Phosphotyrosine(EGFR)HMM predict
3915Phosphoserine(IKK)HMM predict
3948Phosphothreonine(PKA)HMM predict
3980Phosphoserine(CDC2)HMM predict
3999O-linkedHMM predict
4027Phosphoserine(CDC2)HMM predict
4027Phosphoserine(CDK)HMM predict
4031Phosphoserine(CDC2)HMM predict
4031Phosphoserine(CDK)HMM predict
4048Phosphoserine(PKG)HMM predict
4096Phosphothreonine(PKC)HMM predict
4141Phosphotyrosine(SRC)HMM predict
4211Phosphotyrosine(INSR)HMM predict
4232Phosphotyrosine(Jak)HMM predict
4237N-linkedHMM predict
4277Phosphoserine(CK1)HMM predict
4388Phosphotyrosine(Syk)HMM predict
4431N-linkedHMM predict
4434Phosphoserine(IKK)HMM predict
4438Phosphoserine(IKK)HMM predict
4510Phosphotyrosine(Syk)HMM predict
4510Phosphotyrosine(EGFR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000384
  • Location:chr2 21077806-21120449
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 21123242 21123984 742 3164
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 21065287 21065576 289 12375
CTCF G2GSE9613 21067517 21067647 130 10225
CTCF G2GSE9613 21070361 21070678 317 7287
TFAP2C MCF7GSE21234 21068786 21069198 412 8815
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 21119126 21119540 414 0
CTCF CD4SISSRdata 21119126 21119540 414 0
CTCF G2GSE9613 21104006 21104168 162 0
CTCF G2GSE9613 21112784 21112914 130 0
CTCF G2GSE9613 21119136 21120507 1371 0
H3ac HepG2E 21116686 21119208 2522 0
H3ac HepG2E 21119465 21120035 570 0
Oct1 HelaGSE14283 21101564 21101595 31 0
hScc1 BcellGSE12603 21119172 21119739 567 0
hScc1 BcellGSE12603 21120148 21120507 359 0
hScc1 CdLSGSE12603 21118773 21119739 966 0
hScc1 G2GSE9613 21119172 21120148 976 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
13999 EST chr2 21158019 21158694 168 mRNA APOB chr2 21135952 21178597Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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