AutismKB 2.0

Annotation Detail for ID2


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Basic Information Top
Gene Symbol:ID2 ( GIG8,ID2A,ID2H,MGC26389,bHLHb26 )
Gene Full Name: inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
Band: 2p25.1
Quick LinksEntrez ID:3398; OMIM: 600386; Uniprot ID:ID2_HUMAN; ENSEMBL ID: ENSG00000115738; HGNC ID: 5361
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
115Nuclear export signal (By similarity).
Location(AA) Modifications Resource
5Phosphoserine (CDK2)Phospho.ELM 6.0
Location(AA) Modification Resource
5Phosphoserine(CDC2)HMM predict
5Phosphoserine(CDK)HMM predict
16Phosphoserine(CK1)HMM predict
16Phosphoserine(CK2)HMM predict
99O-linkedHMM predict
101Phosphothreonine(MAPK)HMM predict
101Phosphothreonine(CDK)HMM predict
127N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002166
  • Location:chr2 8739563-8742031
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 8734945 8735602 657 4290
H3K4me3 colorectalcancer 8737435 8737944 509 1874
H3K4me3 colorectalcancer 8738467 8739024 557 818
H3ac HepG2E 8736717 8738007 1290 2202
Oct1 H2O2-HelaGSE14283 8738025 8738053 28 1525
Oct1 HelaGSE14283 8738023 8738054 31 1525
P300 T0-glioblastomaGSE21026 8719838 8720706 868 19292
P300 T30-glioblastomaGSE21026 8719744 8720722 978 19331
PolII HeLaGSE12783 8734734 8741433 6699 1480
TAF HelaGSE8489 8736972 8737872 900 2142
USF1 HepG2E 8736682 8739189 2507 1628
USF2 HepG2E 8736825 8739158 2333 1572
p130 shRbQuiescentGSE19898 8736914 8737212 298 2501
p130 shRbSenescentGSE19898 8736602 8736895 293 2815
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 8743427 8743719 292 1542
CTCF CD4GSE12889 8750839 8751084 245 8930
CTCF CD4SISSRdata 8743427 8743719 292 1542
CTCF CD4SISSRdata 8750839 8751084 245 8930
CTCF G2GSE9613 8742612 8743804 1192 1177
CTCF G2GSE9613 8750449 8751188 739 8787
CTCF G2GSE9613 8751867 8752103 236 9954
KLF4 hESGSE17917 8751550 8751932 382 9710
TFAP2C MCF7GSE21234 8741997 8742749 752 342
hScc1 BcellGSE12603 8742939 8743841 902 1359
hScc1 BcellGSE12603 8750925 8751188 263 9025
hScc1 CdLSGSE12603 8742792 8743956 1164 1343
hScc1 G2GSE9613 8742734 8743956 1222 1314
hScc1 G2GSE9613 8750702 8751188 486 8914
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 8739405 8739980 575 0
Fos K562GSE19551 8739350 8740014 664 0
H3K4me2 HCT116GSE10453 8740418 8741055 637 0
H3K4me3 colorectalcancer 8739942 8741661 1719 0
H3ac HepG2E 8739693 8742396 2703 0
Pol2 GM12878GSE19551 8739394 8740034 640 0
TAF HelaGSE8489 8739980 8741055 1075 0
TAF k562GSE8489 8739980 8741552 1572 0
hScc1 BcellGSE12603 8739500 8740164 664 0
hScc1 G2GSE9613 8739216 8740201 985 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-125b hsa-mir-125b-1 11 18056640
hsa-miR-125b hsa-mir-125b-2 21 18056640
hsa-miR-206 hsa-mir-206 6 21041476
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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