Annotation Detail for TXNDC6

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Basic Information Top

Gene Symbol:	TXNDC6 ( MGC129586,NME9,TXL-2,TXL2 )
Gene Full Name:	thioredoxin domain containing 6
Band:	3q22.3
Quick Links	Entrez ID:347736; OMIM: NA; Uniprot ID:TXND6_HUMAN; ENSEMBL ID: ENSG00000181322; HGNC ID:
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:0 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:5 results

No data

Location(AA)	Modification	Resource
39	S-palmitoyl	HMM predict
135	Phosphoserine(CK1)	HMM predict
135	Phosphoserine(CK2)	HMM predict
198	Phosphothreonine(PKC)	HMM predict
224	Phosphoserine(ATM)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_178130
Location:chr3 139462968-139531417
strand:-

Upstream the gene:13 results
Downstream the gene:0 results
Inside the gene:16 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	139549562	139551023	1461	18875
FOXA1	MCF7	GSE15244	139531200	139531696	496	31
RARG	MCF7	GSE15244	139549489	139549663	174	18159
Rb	Growing	GSE19898	139531442	139531583	141	95
Rb	Growing	GSE19898	139549934	139550193	259	18646
Rb	shRbSenescence	GSE19898	139548098	139548372	274	16818
TFAP2C	MCF7	GSE21234	139546191	139546597	406	14977
hScc1	Bcell	GSE12603	139549489	139550157	668	18406
hScc1	G2	GSE9613	139533971	139534380	409	2758
hScc1	G2	GSE9613	139549808	139550699	891	18836
p130	Quiescent	GSE19898	139549486	139549927	441	18289
p130	shRbQuiescent	GSE19898	139549489	139549831	342	18243
p130	shRbSenescent	GSE19898	139549502	139549861	359	18264

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	139483657	139483827	170	0
CTCF	G2	GSE9613	139486457	139486835	378	0
CTCF	G2	GSE9613	139494332	139494547	215	0
CTCF	G2	GSE9613	139500667	139500812	145	0
CTCF	G2	GSE9613	139505945	139506252	307	0
CTCF	G2	GSE9613	139529660	139531588	1928	0
FOXA1	MCF7	GSE15244	139530519	139530941	422	0
Oct1	H2O2-Hela	GSE14283	139467613	139467674	61	0
Oct1	Hela	GSE14283	139527190	139527235	45	0
TFAP2C	MCF7	GSE21234	139530555	139530944	389	0
hScc1	Bcell	GSE12603	139519697	139519951	254	0
hScc1	Bcell	GSE12603	139530556	139531588	1032	0
hScc1	CdLS	GSE12603	139530519	139530941	422	0
hScc1	G2	GSE9613	139530519	139531588	1069	0
p130	shRbSenescent	GSE19898	139531095	139531702	607	0
p63	keratinocytes	GSE17611	139483419	139484343	924	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
18736	mRNA	ARMC8	chr3	139388845	139498917	35941	mRNA	TXNDC6	chr3	139462976	139531426	Non-exonic Bidirectional (NOB) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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