AutismKB 2.0

Annotation Detail for IGFBP4


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Basic Information Top
Gene Symbol:IGFBP4 ( BP-4,HT29-IGFBP,IBP4,IGFBP-4 )
Gene Full Name: insulin-like growth factor binding protein 4
Band: 17q21.2
Quick LinksEntrez ID:3487; OMIM: 146733; Uniprot ID:IBP4_HUMAN; ENSEMBL ID: ENSG00000141753; HGNC ID: 5473
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
125N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
125N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
76Phosphoserine(IKK)HMM predict
125N-linkedHMM predict
126N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001552
  • Location:chr17 35853201-35867506
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 35843521 35843736 215 9573
CTCF CD4GSE12889 35850842 35851062 220 2250
CTCF CD4SISSRdata 35843521 35843736 215 9573
CTCF CD4SISSRdata 35850842 35851062 220 2250
CTCF HelaGSE12889 35843483 35843698 215 9611
CTCF G2GSE9613 35843424 35843776 352 9602
CTCF G2GSE9613 35850750 35851114 364 2270
TFAP2C MCF7GSE21234 35852350 35853075 725 489
hScc1 BcellGSE12603 35850750 35851216 466 2219
hScc1 CdLSGSE12603 35843564 35843776 212 9532
hScc1 CdLSGSE12603 35850750 35851299 549 2177
hScc1 G2GSE9613 35850750 35851263 513 2195
p130 SenescentGSE19898 35852427 35852648 221 664
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog hESGSE18292 35874642 35874983 341 7306
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 35853557 35853713 156 0
CTCF CD4GSE12889 35860017 35860285 268 0
CTCF CD4SISSRdata 35853557 35853713 156 0
CTCF CD4SISSRdata 35860017 35860285 268 0
CTCF G2GSE9613 35853215 35853511 296 0
ER Breast-CancerGSE22609 35858306 35858844 538 0
ER MCF7GSE19013 35858178 35859032 854 0
FOXA1 MCF7GSE15244 35858242 35859002 760 0
FoxA1 MCF7MACSdata 35858473 35858825 352 0
H3ac HepG2E 35854031 35855182 1151 0
Myc K562GSE19551 35860053 35860291 238 0
Oct1 HelaGSE14283 35859217 35859280 63 0
RARA MCF7GSE15244 35858130 35859092 962 0
RARG MCF7GSE15244 35858165 35859002 837 0
TFAP2C MCF7GSE21234 35858225 35859028 803 0
USF1 HepG2E 35854171 35855595 1424 0
USF1 HepG2E 35856434 35859092 2658 0
USF2 HepG2E 35857455 35859092 1637 0
hScc1 BcellGSE12603 35853215 35853633 418 0
p130 QuiescentGSE19898 35853513 35853653 140 0
p130 shRbQuiescentGSE19898 35862028 35862591 563 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018