Annotation Detail for IGFBP5

View Evidences	View Variants	View Annotations

Basic Information Top

Gene Symbol:	IGFBP5 ( IBP5 )
Gene Full Name:	insulin-like growth factor binding protein 5
Band:	2q35
Quick Links	Entrez ID:3488; OMIM: 146734; Uniprot ID:IBP5_HUMAN; ENSEMBL ID: ENSG00000115461; HGNC ID: 5474
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:1 results
Experimental PTM Sites from dbPTM:2 results
Predicted PTM Sites by profile HMM from dbPTM:3 results

Location(AA)	Modification
172	O-linked (HexNAc...).

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_000599
Location:chr2 217245073-217268515
strand:-

Upstream the gene:8 results
Downstream the gene:2 results
Inside the gene:11 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	217269370	217269780	410	1060
CTCF	G2	GSE9613	217281372	217281737	365	13039
H3K27me3	colorectal	cancer	217267988	217269523	1535	240
H3K27me3	colorectal	cancer	217269895	217271456	1561	2160
H3K27me3	colorectal	cancer	217272808	217273537	729	4657
hScc1	Bcell	GSE12603	217271673	217271876	203	3259
hScc1	G2	GSE9613	217269406	217270332	926	1354
hScc1	G2	GSE9613	217271979	217272329	350	3639

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	217243788	217244071	283	1144
hScc1	Bcell	GSE12603	217243855	217244153	298	1070

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	217255481	217255722	241	0
CTCF	CD4	GSE12889	217260728	217260924	196	0
CTCF	CD4	SISSRdata	217255481	217255722	241	0
CTCF	CD4	SISSRdata	217260728	217260924	196	0
CTCF	G2	GSE9613	217249737	217249921	184	0
CTCF	G2	GSE9613	217251737	217252352	615	0
CTCF	G2	GSE9613	217267268	217267927	659	0
ER	MCF7	GSE19013	217257178	217258265	1087	0
H3K27me3	colorectal	cancer	217266580	217267340	760	0
Rb	shRbQuiescent	GSE19898	217266345	217266584	239	0
TFAP2C	MCF7	GSE21234	217256742	217257421	679	0

Validated miRNA targets

miR Walk:16 results
Tarbase V5.0:0 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-125a-3p	hsa-mir-125a	19	19950226
hsa-miR-125a-5p	hsa-mir-125a	19	19950226
hsa-miR-140-3p	hsa-mir-140	16	19948051
hsa-miR-140-3p	hsa-mir-140	16	19950226
hsa-miR-140-5p	hsa-mir-140	16	19948051
hsa-miR-140-5p	hsa-mir-140	16	19950226
hsa-miR-149	hsa-mir-149	2	19950226
hsa-miR-149*	hsa-mir-149	2	19950226
hsa-miR-27a	hsa-mir-27a	19	19948051
hsa-miR-27a	hsa-mir-27a	19	19950226
hsa-miR-27a*	hsa-mir-27a	19	19948051
hsa-miR-27a*	hsa-mir-27a	19	19950226
hsa-miR-423-3p	hsa-mir-423	17	19950226
hsa-miR-423-5p	hsa-mir-423	17	19950226
hsa-miR-92a	hsa-mir-92a-1	13	19950226
hsa-miR-92a-1*	hsa-mir-92a-1	13	19950226

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved