Annotation Detail for TICAM2

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Basic Information Top

Gene Symbol:	TICAM2 ( MGC129876,MGC129877,TICAM-2,TIRAP3,TIRP,TRAM )
Gene Full Name:	toll-like receptor adaptor molecule 2
Band:	5q22.3
Quick Links	Entrez ID:353376; OMIM: 608321; Uniprot ID:TCAM2_HUMAN; ENSEMBL ID: ENSG00000243414; HGNC ID: 21354
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
16	Phosphoserine; by PKC/PRKCE.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	114998356	114998563	207	8850
CTCF	CD4	SISSRdata	114998356	114998563	207	8850
CTCF	Jurkat	GSE12889	114998342	114998514	172	8819
CTCF	G2	GSE9613	114998129	114998536	407	8723
ETS1	Jurkat	GSE17954	114989164	114990341	1177	143
Myc	K562	GSE19551	114989222	114990255	1033	129
Myc	K562	GSE19551	114998313	114998560	247	8827
NFkBII	GM12878	GSE19485	115001192	115003690	2498	12832
Oct1	H2O2-Hela	GSE14283	115002047	115002089	42	12459
Oct1	Hela	GSE14283	115002043	115002086	43	12455
Oct4	hES	GSE21916	114998100	114998643	543	8762
PHF8	293T	GSE20725	114989072	114990247	1175	50
Rb	Growing	GSE19898	114998416	114998524	108	8861
TFAP2C	MCF7	GSE21234	114989472	114989932	460	93
TFAP2C	MCF7	GSE21234	115003893	115004323	430	14499
hScc1	Bcell	GSE12603	114998057	114998536	479	8687
hScc1	CdLS	GSE12603	114998021	114998805	784	8804
hScc1	G2	GSE9613	114997985	114998805	820	8786
p130	Senescent	GSE19898	114989467	114990252	785	250

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	114935141	114935354	213	6999
ER	Fulvestrant-MCF7	GSE14664	114931938	114931971	33	10292

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	CD4	GSE12889	114950216	114950384	168
CTCF	CD4	SISSRdata	114950216	114950384	168
CTCF	G2	GSE9613	114950275	114950703	428
CTCF	G2	GSE9613	114965720	114966049	329
NFkBII	GM12878	GSE19485	114940785	114944471	3686
NFkBII	GM12878	GSE19485	114963936	114966951	3015
NFkBII	GM18526	GSE19485	114964816	114966773	1957
Oct1	H2O2-Hela	GSE14283	114966096	114966137	41
Oct1	Hela	GSE14283	114966096	114966137	41
Oct1	Hela	GSE14283	114969118	114969158	40
PHF8	HeLa	GSE20725	114988885	114990323	1438
PHF8	Hs68plusFBS	GSE20725	114965042	114966555	1513
Rb	Quiescent	GSE19898	114947203	114947336	133
TFAP2C	MCF7	GSE21234	114963117	114963420	303
hScc1	Bcell	GSE12603	114949912	114950676	764
hScc1	CdLS	GSE12603	114949840	114951403	1563
hScc1	CdLS	GSE12603	114965329	114965834	505
hScc1	G2	GSE9613	114949948	114951022	1074

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
21343	EST		chr5	114966640	114984255	225	mRNA	TICAM2	chr5	114942246	114989610	Sense/Antisense (SA) pairs

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018