Annotation Detail for IL1B

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Basic Information Top

Gene Symbol:	IL1B ( IL-1,IL1-BETA,IL1F2 )
Gene Full Name:	interleukin 1, beta
Band:	2q14.1
Quick Links	Entrez ID:3553; OMIM: 147720; Uniprot ID:IL1B_HUMAN; ENSEMBL ID: ENSG00000125538; HGNC ID: 5992
Relate to Another Database:	SFARIGene; denovo-db

General

Expression

Regulation

Pathways, Diseases and Drugs

PTM

TF binding site

miRNA targets

Cis-NATs

Post Translation Modification

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PTM Sites from Uniprot:0 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:3 results

No data

Location(AA)	Modification	Resource
123	N-linked	HMM predict
129	Phosphoserine(ATM)	HMM predict
133	Phosphoserine(IKK)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_000576
Location:chr2 113303807-113310826
strand:-

Upstream the gene:3 results
Downstream the gene:3 results
Inside the gene:1 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
P300	T30-glioblastoma	GSE21026	113310646	113311484	838	239
TAF	k562	GSE8489	113321488	113321850	362	10843
hScc1	Bcell	GSE12603	113327081	113327321	240	16375

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
NFkBII	GM12878	GSE19485	113285413	113287646	2233	17278
NFkBII	GM12892	GSE19485	113285540	113287668	2128	17204
Nanog	hES	GSE18292	113295001	113295313	312	8651

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	113307538	113307724	186	0

Validated miRNA targets

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miR Walk:154 results
Tarbase V5.0:0 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7a	hsa-let-7a-1	9	21085987
hsa-let-7a	hsa-let-7a-2	11	21085987
hsa-let-7a	hsa-let-7a-3	22	21085987
hsa-let-7a	hsa-let-7a-1	9	18759964
hsa-let-7a	hsa-let-7a-2	11	18759964
hsa-let-7a	hsa-let-7a-3	22	18759964
hsa-let-7g	hsa-let-7g	3	21085987
hsa-let-7g*	hsa-let-7g	3	21085987
hsa-miR-103	hsa-mir-103-2	20	19011694
hsa-miR-103	hsa-mir-103-1	5	19011694
hsa-miR-126	hsa-mir-126	9	20083669
hsa-miR-126*	hsa-mir-126	9	20083669
hsa-miR-1274a	hsa-mir-1274a	0	21085987
hsa-miR-130a	hsa-mir-130a	11	20716963
hsa-miR-130a*	hsa-mir-130a	11	20716963
hsa-miR-130b	hsa-mir-130b	22	20716963
hsa-miR-130b*	hsa-mir-130b	22	20716963
hsa-miR-132	hsa-mir-132	17	18759964
hsa-miR-132	hsa-mir-132	17	16885212
hsa-miR-132*	hsa-mir-132	17	18759964
hsa-miR-132*	hsa-mir-132	17	16885212
hsa-miR-133a	hsa-mir-133a-1	18	20520763
hsa-miR-133a	hsa-mir-133a-2	20	20520763
hsa-miR-140-3p	hsa-mir-140	16	19714579
hsa-miR-140-5p	hsa-mir-140	16	19714579
hsa-miR-142-5p	hsa-mir-142	17	21085987
hsa-miR-146a	hsa-mir-146a	5	21279994
hsa-miR-146a	hsa-mir-146a	5	21263019
hsa-miR-146a	hsa-mir-146a	5	20981815
hsa-miR-146a	hsa-mir-146a	5	20937840
hsa-miR-146a	hsa-mir-146a	5	20934487
hsa-miR-146a	hsa-mir-146a	5	20716963
hsa-miR-146a	hsa-mir-146a	5	20525168
hsa-miR-146a	hsa-mir-146a	5	20522791
hsa-miR-146a	hsa-mir-146a	5	20520763
hsa-miR-146a	hsa-mir-146a	5	20148189
hsa-miR-146a	hsa-mir-146a	5	20086228
hsa-miR-146a	hsa-mir-146a	5	19333945
hsa-miR-146a	hsa-mir-146a	5	19167348
hsa-miR-146a	hsa-mir-146a	5	19008124
hsa-miR-146a	hsa-mir-146a	5	18759964
hsa-miR-146a	hsa-mir-146a	5	18504431
hsa-miR-146a	hsa-mir-146a	5	18438844
hsa-miR-146a	hsa-mir-146a	5	18390754
hsa-miR-146a	hsa-mir-146a	5	16885212
hsa-miR-146a*	hsa-mir-146a	5	21279994
hsa-miR-146a*	hsa-mir-146a	5	21263019
hsa-miR-146a*	hsa-mir-146a	5	20981815
hsa-miR-146a*	hsa-mir-146a	5	20937840
hsa-miR-146a*	hsa-mir-146a	5	20934487
hsa-miR-146a*	hsa-mir-146a	5	20716963
hsa-miR-146a*	hsa-mir-146a	5	20525168
hsa-miR-146a*	hsa-mir-146a	5	20522791
hsa-miR-146a*	hsa-mir-146a	5	20520763
hsa-miR-146a*	hsa-mir-146a	5	20148189
hsa-miR-146a*	hsa-mir-146a	5	20086228
hsa-miR-146a*	hsa-mir-146a	5	19333945
hsa-miR-146a*	hsa-mir-146a	5	19167348
hsa-miR-146a*	hsa-mir-146a	5	19008124
hsa-miR-146a*	hsa-mir-146a	5	18759964
hsa-miR-146a*	hsa-mir-146a	5	18504431
hsa-miR-146a*	hsa-mir-146a	5	18438844
hsa-miR-146a*	hsa-mir-146a	5	18390754
hsa-miR-146a*	hsa-mir-146a	5	16885212
hsa-miR-146b-3p	hsa-mir-146b	10	20716963
hsa-miR-146b-3p	hsa-mir-146b	10	20520763
hsa-miR-146b-3p	hsa-mir-146b	10	20148189
hsa-miR-146b-3p	hsa-mir-146b	10	19333945
hsa-miR-146b-3p	hsa-mir-146b	10	19008124
hsa-miR-146b-3p	hsa-mir-146b	10	18504431
hsa-miR-146b-3p	hsa-mir-146b	10	18438844
hsa-miR-146b-3p	hsa-mir-146b	10	18390754
hsa-miR-146b-3p	hsa-mir-146b	10	16885212
hsa-miR-146b-3p	hsa-mir-146b	10	19786024
hsa-miR-146b-5p	hsa-mir-146b	10	20716963
hsa-miR-146b-5p	hsa-mir-146b	10	20520763
hsa-miR-146b-5p	hsa-mir-146b	10	20148189
hsa-miR-146b-5p	hsa-mir-146b	10	19333945
hsa-miR-146b-5p	hsa-mir-146b	10	19008124
hsa-miR-146b-5p	hsa-mir-146b	10	18504431
hsa-miR-146b-5p	hsa-mir-146b	10	18438844
hsa-miR-146b-5p	hsa-mir-146b	10	18390754
hsa-miR-146b-5p	hsa-mir-146b	10	16885212
hsa-miR-146b-5p	hsa-mir-146b	10	19786024
hsa-miR-155	hsa-mir-155	21	21279994
hsa-miR-155	hsa-mir-155	21	20981815
hsa-miR-155	hsa-mir-155	21	20950585
hsa-miR-155	hsa-mir-155	21	19701459
hsa-miR-155	hsa-mir-155	21	19193853
hsa-miR-155	hsa-mir-155	21	18759964
hsa-miR-155	hsa-mir-155	21	16885212
hsa-miR-155*	hsa-mir-155	21	21279994
hsa-miR-155*	hsa-mir-155	21	20981815
hsa-miR-155*	hsa-mir-155	21	20950585
hsa-miR-155*	hsa-mir-155	21	19701459
hsa-miR-155*	hsa-mir-155	21	19193853
hsa-miR-155*	hsa-mir-155	21	18759964
hsa-miR-155*	hsa-mir-155	21	16885212
hsa-miR-16	hsa-mir-16-1	13	18759964
hsa-miR-16	hsa-mir-16-2	3	18759964
hsa-miR-16-1*	hsa-mir-16-1	13	18759964
hsa-miR-188-3p	hsa-mir-188	X	19541842
hsa-miR-188-5p	hsa-mir-188	X	19541842
hsa-miR-192	hsa-mir-192	11	21085987
hsa-miR-192*	hsa-mir-192	11	21085987
hsa-miR-193a-3p	hsa-mir-193a	17	21085987
hsa-miR-199b-3p	hsa-mir-199b	9	20716963
hsa-miR-199b-5p	hsa-mir-199b	9	20716963
hsa-miR-203	hsa-mir-203	14	21279994
hsa-miR-203	hsa-mir-203	14	21093440
hsa-miR-203	hsa-mir-203	14	20981815
hsa-miR-20a	hsa-mir-20a	13	21085987
hsa-miR-20a*	hsa-mir-20a	13	21085987
hsa-miR-21	hsa-mir-21	17	21093440
hsa-miR-21	hsa-mir-21	17	20086228
hsa-miR-21*	hsa-mir-21	17	21093440
hsa-miR-21*	hsa-mir-21	17	20086228
hsa-miR-22	hsa-mir-22	17	19011694
hsa-miR-22*	hsa-mir-22	17	19011694
hsa-miR-221	hsa-mir-221	X	20716963
hsa-miR-221*	hsa-mir-221	X	20716963
hsa-miR-25	hsa-mir-25	7	19541842
hsa-miR-25*	hsa-mir-25	7	19541842
hsa-miR-26b	hsa-mir-26b	2	21085987
hsa-miR-26b*	hsa-mir-26b	2	21085987
hsa-miR-27b	hsa-mir-27b	9	20131257
hsa-miR-27b*	hsa-mir-27b	9	20131257
hsa-miR-296-3p	hsa-mir-296	20	20716963
hsa-miR-296-5p	hsa-mir-296	20	20716963
hsa-miR-29b	hsa-mir-29b-1	7	20716963
hsa-miR-29b	hsa-mir-29b-2	1	20716963
hsa-miR-329	hsa-mir-329-1	14	20716963
hsa-miR-329	hsa-mir-329-2	14	20716963
hsa-miR-342-3p	hsa-mir-342	14	20716963
hsa-miR-342-5p	hsa-mir-342	14	20716963
hsa-miR-34a	hsa-mir-34a	1	20675358
hsa-miR-34a	hsa-mir-34a	1	20086228
hsa-miR-34a*	hsa-mir-34a	1	20675358
hsa-miR-34a*	hsa-mir-34a	1	20086228
hsa-miR-377	hsa-mir-377	14	21085987
hsa-miR-377*	hsa-mir-377	14	21085987
hsa-miR-382	hsa-mir-382	14	20716963
hsa-miR-409-3p	hsa-mir-409	14	20716963
hsa-miR-409-5p	hsa-mir-409	14	20716963
hsa-miR-450b-5p	hsa-mir-450b	X	21085987
hsa-miR-9	hsa-mir-9-1	1	19289835
hsa-miR-9	hsa-mir-9-2	5	19289835
hsa-miR-9	hsa-mir-9-3	15	19289835
hsa-miR-9	hsa-mir-9-1	1	19008124
hsa-miR-9	hsa-mir-9-2	5	19008124
hsa-miR-9	hsa-mir-9-3	15	19008124
hsa-miR-9*	hsa-mir-9-1	1	19289835
hsa-miR-98	hsa-mir-98	X	21085987
hsa-miR-98	hsa-mir-98	X	19008124

Cis-Nats regulation

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Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

AutismKB 2.0

Annotation Detail for IL1B

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics