AutismKB 2.0

Annotation Detail for IL10RA


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Basic Information Top
Gene Symbol:IL10RA ( CDW210A,HIL-10R,IL-10R1,IL10R )
Gene Full Name: interleukin 10 receptor, alpha
Band: 11q23.3
Quick LinksEntrez ID:3587; OMIM: 146933; Uniprot ID:I10R1_HUMAN; ENSEMBL ID: ENSG00000110324; HGNC ID: 5964
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
50N-linked (GlcNAc...) (Potential).
74N-linked (GlcNAc...) (Potential).
110N-linked (GlcNAc...) (Potential).
154N-linked (GlcNAc...) (Potential).
177N-linked (GlcNAc...) (Potential).
189N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
50N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
74N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
110N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
154N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
177N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
189N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
446Phosphotyrosine (Tyk2)Phospho.ELM 6.0
496Phosphotyrosine (Tyk2)Phospho.ELM 6.0
Location(AA) Modification Resource
24O-linkedHMM predict
28Phosphoserine(MAPK)HMM predict
50N-linkedHMM predict
74N-linkedHMM predict
76Phosphoserine(ATM)HMM predict
110N-linkedHMM predict
115N-linkedHMM predict
154N-linkedHMM predict
157Phosphotyrosine(Syk)HMM predict
157Phosphotyrosine(EGFR)HMM predict
177N-linkedHMM predict
191Phosphoserine(CK1)HMM predict
225Phosphoserine(CK1)HMM predict
286Phosphoserine(CDK)HMM predict
286Phosphoserine(CDC2)HMM predict
286Phosphoserine(IKK)HMM predict
362Phosphoserine(CK1)HMM predict
366N-linkedHMM predict
378O-linkedHMM predict
380Phosphoserine(CDC2)HMM predict
380Phosphoserine(ATM)HMM predict
380O-linkedHMM predict
426Phosphoserine(ATM)HMM predict
509O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001558
  • Location:chr11 117362318-117377402
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 117348536 117349841 1305 13130
RARA MCF7GSE15244 117349329 117349694 365 12807
TAF HelaGSE8489 117346101 117346608 507 15964
hScc1 CdLSGSE12603 117355701 117356081 380 6428
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 117387948 117388628 680 10886
GATA3 MCF7GSE15244 117391057 117392026 969 14139
NFkBII GM10847GSE19485 117386069 117387507 1438 9386
NFkBII GM12878GSE19485 117386276 117388773 2497 10122
NFkBII GM12892GSE19485 117385680 117388905 3225 9890
NFkBII GM15510GSE19485 117385600 117388691 3091 9743
NFkBII GM18526GSE19485 117385880 117388875 2995 9975
Stat6 IL-4-hr1GSE17850 117378211 117379154 943 1280
hScc1 BcellGSE12603 117386732 117387195 463 9561
hScc1 CdLSGSE12603 117386828 117387301 473 9662
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 117375290 117375981 691 0
hScc1 BcellGSE12603 117362835 117363198 363 0
hScc1 BcellGSE12603 117373863 117374043 180 0
hScc1 CdLSGSE12603 117362451 117363575 1124 0
hScc1 CdLSGSE12603 117373863 117374571 708 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018