AutismKB 2.0

Annotation Detail for FOXK2


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Basic Information Top
Gene Symbol:FOXK2 ( ILF,ILF-1,ILF1 )
Gene Full Name: forkhead box K2
Band: 17q25.3
Quick LinksEntrez ID:3607; OMIM: 147685; Uniprot ID:FOXK2_HUMAN; ENSEMBL ID: ENSG00000141568; HGNC ID: 6036
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
13Phosphothreonine.
30Phosphoserine.
61Phosphoserine.
239Phosphoserine.
398Phosphoserine.
428Phosphoserine.
Location(AA) Modifications Resource
398Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
9O-linkedHMM predict
9O-linkedHMM predict
13Phosphothreonine(MAPK)HMM predict
59N-linkedHMM predict
61Phosphoserine(ATM)HMM predict
64Phosphoserine(PKA)HMM predict
170Phosphoserine(CDC2)HMM predict
170PhosphoserineHMM predict
170Phosphoserine(CDK)HMM predict
180Phosphoserine(ATM)HMM predict
195Phosphoserine(MAPK)HMM predict
195O-linkedHMM predict
199Phosphoserine(CDK)HMM predict
199Phosphoserine(CDC2)HMM predict
203O-linkedHMM predict
209Phosphoserine(IKK)HMM predict
212Phosphoserine(CK1)HMM predict
212O-linkedHMM predict
213Phosphoserine(CDK)HMM predict
213Phosphoserine(CDC2)HMM predict
239Phosphoserine(IKK)HMM predict
239Phosphoserine(ATM)HMM predict
252Phosphoserine(ATM)HMM predict
322Phosphoserine(IKK)HMM predict
322Phosphoserine(ATM)HMM predict
360Phosphothreonine(CDK)HMM predict
360Phosphothreonine(CDC2)HMM predict
367O-linkedHMM predict
373Phosphoserine(CDK)HMM predict
384Phosphoserine(CK1)HMM predict
385O-linkedHMM predict
389Phosphothreonine(CDK)HMM predict
389Phosphothreonine(CDC2)HMM predict
389Phosphothreonine(MAPK)HMM predict
394Phosphoserine(CK1)HMM predict
398PhosphoserineHMM predict
398Phosphoserine(IKK)HMM predict
428O-linkedHMM predict
428Phosphoserine(IKK)HMM predict
428Phosphoserine(CDC2)HMM predict
428PhosphoserineHMM predict
431O-linkedHMM predict
432Phosphoserine(ATM)HMM predict
456O-linkedHMM predict
459O-linkedHMM predict
460O-linkedHMM predict
461O-linkedHMM predict
461Phosphoserine(IKK)HMM predict
461O-linkedHMM predict
463O-linkedHMM predict
495O-linkedHMM predict
497O-linkedHMM predict
503O-linkedHMM predict
552Phosphothreonine(CDK)HMM predict
578N-linkedHMM predict
584Phosphoserine(CAMK2)HMM predict
609O-linkedHMM predict
611O-linkedHMM predict
613Phosphoserine(IKK)HMM predict
616Phosphothreonine(PKC)HMM predict
634Phosphothreonine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004514
  • Location:chr17 78070882-78155769
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 78070626 78070819 193 160
ETS1 JurkatGSE17954 78070262 78071123 861 190
Fos K562GSE19551 78070121 78071137 1016 254
USF2 HepG2E 78068376 78068567 191 2411
hScc1 BcellGSE12603 78070254 78070819 565 346
hScc1 CdLSGSE12603 78070405 78070819 414 271
p130 QuiescentGSE19898 78070227 78070467 240 536
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
p63 keratinocytesGSE17611 78157175 78158060 885 1848
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 78103032 78103374 342 0
CTCF CD4GSE12889 78105545 78105889 344 0
CTCF CD4SISSRdata 78103032 78103374 342 0
CTCF CD4SISSRdata 78105545 78105889 344 0
CTCF G2GSE9613 78071151 78071616 465 0
CTCF G2GSE9613 78105526 78105878 352 0
CTCF G2GSE9613 78130779 78131496 717 0
CTCF G2GSE9613 78149958 78150234 276 0
ER Fulvestrant-MCF7GSE14664 78099222 78099257 35 0
ER MCF7GSE19013 78073072 78073736 664 0
H3K4me3 colorectalcancer 78071891 78072309 418 0
H3ac HepG2E 78071663 78072309 646 0
H3ac HepG2E 78112216 78113079 863 0
Myc K562GSE19551 78102966 78103383 417 0
Myc hESGSE17917 78071043 78071440 397 0
NRSF JurkatSISSRdata 78103064 78103235 171 0
Oct1 HelaGSE14283 78121914 78121957 43 0
Oct4 hESGSE21916 78104424 78104994 570 0
PHF8 HeLaGSE20725 78070064 78071791 1727 0
RARA MCF7GSE15244 78071926 78072309 383 0
RARA MCF7GSE15244 78144011 78144572 561 0
Rb SenescentGSE19898 78103160 78103384 224 0
TAF k562GSE8489 78071817 78072309 492 0
TFAP2C MCF7GSE21234 78073188 78073700 512 0
TFAP2C MCF7GSE21234 78085515 78086006 491 0
USF1 HepG2E 78072069 78072309 240 0
USF2 HepG2E 78071957 78072309 352 0
USF2 HepG2E 78119370 78119780 410 0
hScc1 BcellGSE12603 78071151 78071663 512 0
hScc1 BcellGSE12603 78102884 78103588 704 0
hScc1 BcellGSE12603 78104411 78104867 456 0
hScc1 BcellGSE12603 78130734 78131947 1213 0
hScc1 CdLSGSE12603 78102884 78103588 704 0
hScc1 CdLSGSE12603 78105313 78105878 565 0
p130 QuiescentGSE19898 78087674 78087975 301 0
p130 shRbQuiescentGSE19898 78087222 78088011 789 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
11791 mRNA FOXK2 chr17 78070882 78153743 1915 mRNA PRO0478 chr17 78073230 78075145 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018