Annotation Detail for ILF2

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Basic Information Top

Gene Symbol:	ILF2 ( MGC8391,NF45,PRO3063 )
Gene Full Name:	interleukin enhancer binding factor 2, 45kDa
Band:	1q21.3
Quick Links	Entrez ID:3608; OMIM: 603181; Uniprot ID:ILF2_HUMAN; ENSEMBL ID: ENSG00000143621; HGNC ID: 6037
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:1 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:11 results

Location(AA)	Modification
388	Phosphothreonine.

Location(AA)	Modification	Resource
16	Methylarginine	HMM predict
145	Phosphoserine(PKC)	HMM predict
160	N-linked	HMM predict
214	N-linked	HMM predict
256	N-linked	HMM predict
352	Phosphothreonine(MAPK)	HMM predict
352	Phosphothreonine(CDK)	HMM predict
358	Phosphotyrosine(SRC)	HMM predict
358	Phosphotyrosine(INSR)	HMM predict
358	Phosphotyrosine(Syk)	HMM predict
385	Phosphoserine(CK1)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_004515
Location:chr1 151901138-151910102
strand:-

Upstream the gene:11 results
Downstream the gene:0 results
Inside the gene:8 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
Fos	K562	GSE19551	151909792	151910796	1004	192
Nanog	ES	GSE20650	151909943	151910694	751	216
Nanog	hES	GSE18292	151910102	151910645	543	271
Oct4	ES	GSE20650	151910209	151910496	287	250
P300	T0-glioblastoma	GSE21026	151909622	151910914	1292	166
PHF8	Hs68plusFBS	GSE20725	151909361	151910962	1601	59
Pol3	GM12878	GSE19551	151910001	151910768	767	282
Pol3	K562	GSE19551	151909962	151910837	875	297
RARA	MCF7	GSE15244	151909995	151910664	669	227
Sox2	hES	GSE18292	151910113	151910394	281	151
TAFII	hES	GSE17917	151909948	151910406	458	75

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	151909879	151910211	332	0
H3K4me2	HCT116	GSE10453	151908858	151909599	741	0
H3K4me3	colorectal	cancer	151908858	151909844	986	0
H3ac	HepG2	E	151908858	151910664	1806	0
LIN9	S	GSE7516	151909692	151910471	779	0
Oct1	Hela	GSE14283	151909910	151909938	28	0
PHF8	Hs68minusFBS	GSE20725	151909203	151910926	1723	0
p130	shRbQuiescent	GSE19898	151909439	151910356	917	0

Validated miRNA targets

miR Walk:5 results
Tarbase V5.0:0 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7a	hsa-let-7a-1	9	19398578
hsa-let-7a	hsa-let-7a-2	11	19398578
hsa-let-7a	hsa-let-7a-3	22	19398578
hsa-miR-21	hsa-mir-21	17	19398578
hsa-miR-21*	hsa-mir-21	17	19398578

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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