AutismKB 2.0

Annotation Detail for INCENP


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Basic Information Top
Gene Symbol:INCENP ( FLJ31633,MGC111393 )
Gene Full Name: inner centromere protein antigens 135/155kDa
Band: 11q12.3
Quick LinksEntrez ID:3619; OMIM: 604411; Uniprot ID:INCE_HUMAN; ENSEMBL ID: ENSG00000149503; HGNC ID: 6058
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
50Phosphoserine.
72Phosphoserine.
73Phosphotyrosine.
91Phosphoserine.
93Phosphoserine.
94Phosphoserine.
103Phosphoserine.
106Phosphoserine.
119Phosphoserine.
142Phosphoserine.
143Phosphoserine.
145Phosphothreonine.
148Phosphoserine.
150Phosphothreonine.
195Phosphothreonine.
197Phosphoserine.
199Phosphothreonine.
213Phosphothreonine.
214Phosphoserine.
218Phosphoserine.
219Phosphothreonine.
230Phosphoserine.
235Phosphoserine.
239Phosphothreonine.
263Phosphoserine.
269Phosphoserine.
275Phosphoserine.
291Phosphoserine.
292Phosphothreonine.
294Phosphothreonine.
296Phosphoserine.
298Phosphothreonine.
306Phosphoserine.
311Phosphoserine.
312Phosphoserine.
314Phosphoserine.
350Phosphoserine.
373Phosphoserine.
400Phosphoserine.
406Phosphothreonine.
411Phosphoserine.
412Phosphothreonine.
420Phosphoserine.
421Phosphoserine.
424Phosphothreonine.
446Phosphoserine.
458Phosphoserine.
476Phosphoserine.
478Phosphothreonine.
480Phosphoserine.
481Phosphoserine.
507Phosphothreonine.
509Phosphothreonine.
510Phosphoserine.
514Phosphoserine.
793Phosphothreonine.
798Phosphoserine.
822Phosphotyrosine.
828Phosphoserine.
831Phosphoserine.
832Phosphothreonine.
892Phosphothreonine.
893Phosphoserine.
894Phosphoserine.
899Phosphoserine.
914Phosphoserine.
Location(AA) Modifications Resource
73Phosphotyrosine.Swiss-Prot 53.0
73PhosphotyrosinePhospho.ELM 6.0
119Phosphoserine.Swiss-Prot 53.0
119PhosphoserinePhospho.ELM 6.0
142Phosphoserine.Swiss-Prot 53.0
142PhosphoserinePhospho.ELM 6.0
143Phosphoserine.Swiss-Prot 53.0
143PhosphoserinePhospho.ELM 6.0
148PhosphoserinePhospho.ELM 6.0
148Phosphoserine.Swiss-Prot 53.0
197Phosphoserine.Swiss-Prot 53.0
197PhosphoserinePhospho.ELM 6.0
199Phosphothreonine.Swiss-Prot 53.0
199PhosphothreoninePhospho.ELM 6.0
213PhosphothreoninePhospho.ELM 6.0
213Phosphothreonine.Swiss-Prot 53.0
214PhosphoserinePhospho.ELM 6.0
214Phosphoserine.Swiss-Prot 53.0
219Phosphothreonine.Swiss-Prot 53.0
219PhosphothreoninePhospho.ELM 6.0
230Phosphoserine.Swiss-Prot 53.0
230PhosphoserinePhospho.ELM 6.0
239Phosphothreonine.Swiss-Prot 53.0
239PhosphothreoninePhospho.ELM 6.0
263Phosphoserine.Swiss-Prot 53.0
263PhosphoserinePhospho.ELM 6.0
269Phosphoserine.Swiss-Prot 53.0
269PhosphoserinePhospho.ELM 6.0
275PhosphoserinePhospho.ELM 6.0
275Phosphoserine.Swiss-Prot 53.0
291PhosphoserinePhospho.ELM 6.0
291Phosphoserine.Swiss-Prot 53.0
292PhosphothreoninePhospho.ELM 6.0
292Phosphothreonine.Swiss-Prot 53.0
294Phosphothreonine.Swiss-Prot 53.0
294PhosphothreoninePhospho.ELM 6.0
296PhosphoserinePhospho.ELM 6.0
296Phosphoserine.Swiss-Prot 53.0
298Phosphothreonine.Swiss-Prot 53.0
306PhosphoserinePhospho.ELM 6.0
306Phosphoserine.Swiss-Prot 53.0
312Phosphoserine.Swiss-Prot 53.0
312PhosphoserinePhospho.ELM 6.0
314Phosphoserine.Swiss-Prot 53.0
314PhosphoserinePhospho.ELM 6.0
421Phosphoserine.Swiss-Prot 53.0
421PhosphoserinePhospho.ELM 6.0
424PhosphothreoninePhospho.ELM 6.0
424Phosphothreonine.Swiss-Prot 53.0
481PhosphoserinePhospho.ELM 6.0
481Phosphoserine.Swiss-Prot 53.0
833PhosphoserinePhospho.ELM 6.0
833Phosphoserine.Swiss-Prot 53.0
836Phosphoserine.Swiss-Prot 53.0
836PhosphoserinePhospho.ELM 6.0
837PhosphothreoninePhospho.ELM 6.0
837Phosphothreonine.Swiss-Prot 53.0
897Phosphothreonine.Swiss-Prot 53.0
897Phosphothreonine (Aurora B)Phospho.ELM 6.0
898Phosphoserine.Swiss-Prot 53.0
898Phosphoserine (Aurora B)Phospho.ELM 6.0
899Phosphoserine.Swiss-Prot 53.0
899Phosphoserine (Aurora B)Phospho.ELM 6.0
904Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
46Phosphothreonine(PKC)HMM predict
50Phosphoserine(PKC)HMM predict
61Phosphoserine(PKC)HMM predict
72Phosphoserine(PKG)HMM predict
87Phosphoserine(PKG)HMM predict
91Phosphoserine(PKA)HMM predict
91Phosphoserine(PKG)HMM predict
91Phosphoserine(IKK)HMM predict
94Phosphoserine(ATM)HMM predict
94Phosphoserine(CK1)HMM predict
94Phosphoserine(IKK)HMM predict
103Phosphoserine(CAMK2)HMM predict
117N-linkedHMM predict
125Phosphothreonine(PKA)HMM predict
142O-linkedHMM predict
143Phosphoserine(CDK)HMM predict
143Phosphoserine(CDC2)HMM predict
143Phosphoserine(MAPK)HMM predict
145Phosphothreonine(CDC2)HMM predict
145Phosphothreonine(CDK)HMM predict
159N-linkedHMM predict
197Phosphoserine(CDC2)HMM predict
197Phosphoserine(CDK)HMM predict
197O-linkedHMM predict
197PhosphoserineHMM predict
199O-linkedHMM predict
202Phosphoserine(IKK)HMM predict
202O-linkedHMM predict
202O-linkedHMM predict
204O-linkedHMM predict
208Phosphoserine(ATM)HMM predict
208O-linkedHMM predict
213Phosphothreonine(CK2)HMM predict
219Phosphothreonine(MAPK)HMM predict
219PhosphothreonineHMM predict
219Phosphothreonine(CDC2)HMM predict
269Phosphoserine(CDC2)HMM predict
289N-linkedHMM predict
300Phosphoserine(ATM)HMM predict
300Phosphoserine(PKA)HMM predict
312Phosphoserine(IKK)HMM predict
312Phosphoserine(CDK)HMM predict
312O-linkedHMM predict
314Phosphoserine(CDC2)HMM predict
314O-linkedHMM predict
398N-linkedHMM predict
399N-linkedHMM predict
404N-linkedHMM predict
410N-linkedHMM predict
412Phosphothreonine(CDC2)HMM predict
412O-linkedHMM predict
414N-linkedHMM predict
420O-linkedHMM predict
421O-linkedHMM predict
421Phosphoserine(IKK)HMM predict
421Phosphoserine(CDK)HMM predict
421Phosphoserine(CDC2)HMM predict
424Phosphothreonine(CDC2)HMM predict
424Phosphothreonine(MAPK)HMM predict
446Phosphoserine(CDK)HMM predict
452Phosphoserine(PKC)HMM predict
452Phosphoserine(PKG)HMM predict
452Phosphoserine(CAMK2)HMM predict
476O-linkedHMM predict
478Phosphothreonine(CDK)HMM predict
481Phosphoserine(CDC2)HMM predict
524Phosphothreonine(CDC2)HMM predict
796N-linkedHMM predict
812Phosphothreonine(CDC2)HMM predict
827Phosphotyrosine(Abl)HMM predict
836Phosphoserine(CK2)HMM predict
837Phosphothreonine(CK2)HMM predict
854Phosphothreonine(CDK)HMM predict
857Phosphoserine(ATM)HMM predict
897Phosphothreonine(PKA)HMM predict
913ProlineHMM predict
915O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001040694
  • Location:chr11 61648020-61677210
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 61632046 61632349 303 15823
CTCF CD4SISSRdata 61632046 61632349 303 15823
ER Fulvestrant-MCF7GSE14664 61647946 61647985 39 55
ETS1 JurkatGSE17954 61647106 61648479 1373 228
Fos K562GSE19551 61647509 61648420 911 56
H3ac HepG2E 61646970 61647472 502 800
Oct1 H2O2-HelaGSE14283 61647953 61647979 26 55
Oct1 HelaGSE14283 61647952 61647982 30 54
PHF8 293TGSE20725 61647270 61648599 1329 86
PHF8 HeLaGSE20725 61636338 61637030 692 11337
STAT1 HeLaGSE12782 61628591 61630561 1970 18445
STAT1 HeLaGSE12783 61628656 61630882 2226 18252
hScc1 BcellGSE12603 61631992 61632611 619 15719
hScc1 CdLSGSE12603 61631992 61632611 619 15719
hScc1 G2GSE9613 61631992 61632611 619 15719
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 61695318 61695557 239 18227
CTCF CD4SISSRdata 61695318 61695557 239 18227
CTCF JurkatGSE12889 61695373 61695518 145 18235
Oct4 hESGSE17917 61695280 61695564 284 18212
hScc1 CdLSGSE12603 61695336 61695727 391 18321
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 G0GSE7516 61647619 61648746 1127 0
FOXA1 MCF7GSE15244 61647803 61648746 943 0
H3ac HepG2E 61647919 61650206 2287 0
LIN54 G0GSE7516 61647803 61648657 854 0
LIN9 G0GSE7516 61647583 61649136 1553 0
LIN9 SGSE7516 61647550 61649100 1550 0
NRSF pAbJurkat 61648204 61648489 285 0
NRSF pAbJurkat 61668767 61669806 1039 0
Oct1 HelaGSE14283 61649146 61649177 31 0
Oct1 HelaGSE14283 61659527 61659566 39 0
PHF8 HeLaGSE20725 61647434 61648907 1473 0
RARA MCF7GSE15244 61649987 61650206 219 0
Rb shRbSenescenceGSE19898 61648326 61648522 196 0
Rb shRbSenescenceGSE19898 61674138 61674387 249 0
TFAP2C MCF7GSE21234 61656211 61656616 405 0
hScc1 BcellGSE12603 61654010 61654322 312 0
hScc1 BcellGSE12603 61664779 61664946 167 0
p130 QuiescentGSE19898 61647754 61648528 774 0
p130 QuiescentGSE19898 61648612 61648721 109 0
p130 SenescentGSE19898 61647652 61649099 1447 0
p130 shRbQuiescentGSE19898 61647723 61649313 1590 0
p130 shRbSenescentGSE19898 61647723 61648750 1027 0
p130 G0GSE7516 61647583 61648746 1163 0
p130 SGSE7516 61647697 61648746 1049 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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