AutismKB 2.0

Annotation Detail for INPPL1


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Basic Information Top
Gene Symbol:INPPL1 ( SHIP2 )
Gene Full Name: inositol polyphosphate phosphatase-like 1
Band: 11q13.4
Quick LinksEntrez ID:3636; OMIM: 600829; Uniprot ID:SHIP2_HUMAN; ENSEMBL ID: ENSG00000165458; HGNC ID: 6080
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
132Phosphoserine.
158Phosphoserine.
165Phosphothreonine.
241Phosphoserine.
671Phosphotyrosine.
886Phosphotyrosine.
949SH3-binding.
958Phosphothreonine.
986Phosphotyrosine; by SRC.
986NPXY motif.
987Phosphotyrosine.
1003Phosphoserine.
1135Phosphotyrosine.
1162Phosphotyrosine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001567
  • Location:chr11 71613472-71627795
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 71612698 71613329 631 459
hScc1 G2GSE9613 71612335 71612876 541 867
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 71626881 71627114 233 0
CTCF CD4SISSRdata 71626881 71627114 233 0
CTCF JurkatGSE12889 71626937 71627180 243 0
H3ac HepG2E 71613978 71614820 842 0
Oct1 HelaGSE14283 71619145 71619172 27 0
TFAP2C MCF7GSE21234 71616050 71616581 531 0
TFAP2C MCF7GSE21234 71626790 71627428 638 0
hScc1 BcellGSE12603 71613440 71613800 360 0
hScc1 BcellGSE12603 71626554 71627092 538 0
hScc1 CdLSGSE12603 71626800 71627237 437 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-184 hsa-mir-184 15 20530248
hsa-miR-184 hsa-mir-184 15 19033458
hsa-miR-205 hsa-mir-205 1 20530248
hsa-miR-205 hsa-mir-205 1 20065103
hsa-miR-205 hsa-mir-205 1 19033458
hsa-miR-21 hsa-mir-21 17 20417062
hsa-miR-21* hsa-mir-21 17 20417062
hsa-miR-221 hsa-mir-221 X 20417062
hsa-miR-221* hsa-mir-221 X 20417062
hsa-miR-222 hsa-mir-222 X 20417062
hsa-miR-222* hsa-mir-222 X 20417062
hsa-miR-224 hsa-mir-224 X 20065103
hsa-miR-335 hsa-mir-335 7 20065103
hsa-miR-335* hsa-mir-335 7 20065103
hsa-miR-424 hsa-mir-424 X 20065103
hsa-miR-424* hsa-mir-424 X 20065103
hsa-miR-451 hsa-mir-451 17 20065103
hsa-miR-491-3p hsa-mir-491 9 20065103
hsa-miR-491-5p hsa-mir-491 9 20065103
hsa-miR-93 hsa-mir-93 7 20065103
hsa-miR-93* hsa-mir-93 7 20065103
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
4857 mRNA INPPL1 chr11 71613472 71627796 27 mRNA PHOX2A chr11 71627769 71632852Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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