AutismKB 2.0

Annotation Detail for ITGA6


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Basic Information Top
Gene Symbol:ITGA6 ( CD49f,DKFZp686J01244,FLJ18737,ITGA6B,VLA-6 )
Gene Full Name: integrin, alpha 6
Band: 2q31.1
Quick LinksEntrez ID:3655; OMIM: 147556; Uniprot ID:ITA6_HUMAN; ENSEMBL ID: ENSG00000091409; HGNC ID: 6142
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
78N-linked (GlcNAc...) (Potential).
223N-linked (GlcNAc...) (Potential).
323N-linked (GlcNAc...).
409N-linked (GlcNAc...) (Potential).
770N-linked (GlcNAc...) (Potential).
787N-linked (GlcNAc...) (Potential).
930N-linked (GlcNAc...) (Potential).
966N-linked (GlcNAc...) (Potential).
997N-linked (GlcNAc...).
1083GFFKR motif.
Location(AA) Modifications Resource
78N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
223N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
323N-linked (GlcNAc...).Swiss-Prot 53.0
409N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
770N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
787N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
930N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
966N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
997N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
78N-linkedHMM predict
109Phosphoserine(CK1)HMM predict
223N-linkedHMM predict
224N-linkedHMM predict
309Phosphoserine(CK2)HMM predict
323N-linkedHMM predict
409N-linkedHMM predict
461Phosphothreonine(PKA)HMM predict
486Phosphotyrosine(Syk)HMM predict
570Phosphoserine(IKK)HMM predict
570Phosphoserine(PKG)HMM predict
570Phosphoserine(PKA)HMM predict
638Phosphoserine(PKG)HMM predict
638Phosphoserine(PKA)HMM predict
720Phosphoserine(CDC2)HMM predict
720Phosphoserine(IKK)HMM predict
726N-linkedHMM predict
728Phosphothreonine(PKA)HMM predict
746O-linkedHMM predict
770N-linkedHMM predict
787N-linkedHMM predict
791Phosphotyrosine(Jak)HMM predict
837Phosphoserine(CK1)HMM predict
930N-linkedHMM predict
936N-linkedHMM predict
964Phosphothreonine(PKC)HMM predict
997N-linkedHMM predict
1005Phosphoserine(CK1)HMM predict
1039O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000210
  • Location:chr2 173000615-173079247
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 172981338 172981751 413 19071
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 173087260 173087515 255 8140
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 173035013 173035402 389 0
CTCF CD4GSE12889 173057368 173057655 287 0
CTCF CD4SISSRdata 173035013 173035402 389 0
CTCF CD4SISSRdata 173057368 173057655 287 0
CTCF G2GSE9613 173000290 173001265 975 0
CTCF G2GSE9613 173034736 173035890 1154 0
CTCF G2GSE9613 173038466 173039199 733 0
CTCF G2GSE9613 173057327 173057720 393 0
FOXA1 MCF7GSE15244 173028183 173028590 407 0
FOXA1 MCF7GSE15244 173038247 173039199 952 0
FoxA1 MCF7MACSdata 173028092 173028394 302 0
H3K4me3 colorectalcancer 173001553 173003019 1466 0
H3ac HepG2E 173001310 173003317 2007 0
Myc K562GSE19551 173038439 173038989 550 0
Oct1 HelaGSE14283 173029896 173029929 33 0
Oct1 HelaGSE14283 173039510 173039579 69 0
Oct1 HelaGSE14283 173067366 173067455 89 0
Stat6 IL-4-hr4GSE17850 173037211 173037859 648 0
TFAP2C MCF7GSE21234 173014791 173015869 1078 0
TFAP2C MCF7GSE21234 173027783 173028622 839 0
hScc1 BcellGSE12603 173000326 173000931 605 0
hScc1 BcellGSE12603 173034944 173035890 946 0
hScc1 BcellGSE12603 173038572 173039271 699 0
hScc1 CdLSGSE12603 173038427 173039271 844 0
hScc1 G2GSE9613 173000290 173001310 1020 0
hScc1 G2GSE9613 173034736 173035754 1018 0
hScc1 G2GSE9613 173038466 173039271 805 0
hScc1 G2GSE9613 173057133 173058000 867 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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