AutismKB 2.0

Annotation Detail for IRF5


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Basic Information Top
Gene Symbol:IRF5 ( SLEB10 )
Gene Full Name: interferon regulatory factor 5
Band: 7q32.1
Quick LinksEntrez ID:3663; OMIM: 607218; Uniprot ID:IRF5_HUMAN; ENSEMBL ID: ENSG00000128604; HGNC ID: 6120
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
10Phosphothreonine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
10Phosphothreonine(CDK)HMM predict
10Phosphothreonine(CDC2)HMM predict
10Phosphothreonine(MAPK)HMM predict
44S-palmitoylHMM predict
118Phosphotyrosine(Syk)HMM predict
128O-linkedHMM predict
130Phosphoserine(ATM)HMM predict
158Phosphoserine(CK1)HMM predict
198O-linkedHMM predict
356Phosphoserine(IKK)HMM predict
389Phosphothreonine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_032643
  • Location:chr7 128365506-128377321
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 128374725 128374832 107 0
CTCF CD4SISSRdata 128374725 128374832 107 0
CTCF G2GSE9613 128366058 128367034 976 0
CTCF G2GSE9613 128367905 128368394 489 0
CTCF G2GSE9613 128372924 128373493 569 0
CTCF G2GSE9613 128374497 128374819 322 0
CTCF G2GSE9613 128375865 128376434 569 0
NFkBII GM12878GSE19485 128363833 128369211 5378 0
NFkBII GM12892GSE19485 128363889 128369184 5295 0
NFkBII GM18526GSE19485 128364424 128369450 5026 0
TFAP2C MCF7GSE21234 128375078 128376015 937 0
hScc1 BcellGSE12603 128368039 128368743 704 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018