AutismKB 2.0

Annotation Detail for ISG20


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Basic Information Top
Gene Symbol:ISG20 ( CD25,HEM45 )
Gene Full Name: interferon stimulated exonuclease gene 20kDa
Band: 15q26.1
Quick LinksEntrez ID:3669; OMIM: 604533; Uniprot ID:ISG20_HUMAN; ENSEMBL ID: ENSG00000172183; HGNC ID: 6130
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
57Phosphoserine(PKG)HMM predict
60Phosphothreonine(MAPK)HMM predict
129Phosphoserine(PKG)HMM predict
129Phosphoserine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002201
  • Location:chr15 86983042-86999882
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 86982457 86983556 1099 36
FOXA1 MCF7GSE15244 86982213 86983844 1631 14
FOXA1 eGFPGSE10845 86982213 86983844 1631 14
H3ac HepG2E 86981945 86982846 901 647
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 87008772 87008942 170 8975
CTCF CD4SISSRdata 87008772 87008942 170 8975
CTCF HelaGSE12889 87001687 87001876 189 1899
CTCF G2GSE9613 87001340 87002143 803 1859
NRSF-mono JurkatQuESTdata 87002015 87002390 375 2320
TFAP2C MCF7GSE21234 87001130 87001446 316 1406
VDR GM10855-UnstimGSE22484 86997990 87002252 4262 239
VDR GM10861-stimGSE22484 86997812 87002486 4674 267
hScc1 BcellGSE12603 87003652 87003909 257 3898
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 86981890 86984221 2331 0
CTCF G2GSE9613 86983063 86983693 630 0
CTCF G2GSE9613 86997643 86998173 530 0
ER MCF7GSE19013 86983449 86983835 386 0
ER MCF7GSE19013 86992835 86993453 618 0
Fos K562GSE19551 86982715 86983459 744 0
Oct1 HelaGSE14283 86986706 86986747 41 0
P300 T0-glioblastomaGSE21026 86982718 86983407 689 0
TFAP2C MCF7GSE21234 86982646 86984055 1409 0
TFAP2C MCF7GSE21234 86991870 86992488 618 0
TFAP2C MCF7GSE21234 86992898 86994123 1225 0
TFAP2C MCF7GSE21234 86996194 86997265 1071 0
hScc1 BcellGSE12603 86982626 86983729 1103 0
hScc1 BcellGSE12603 86997755 86998173 418 0
p130 shRbSenescentGSE19898 86983048 86983744 696 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018