AutismKB 2.0

Annotation Detail for ITGA3


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Basic Information Top
Gene Symbol:ITGA3 ( CD49C,FLJ34631,FLJ34704,GAP-B3,GAPB3,MSK18,VCA-2,VL3A,VLA3a )
Gene Full Name: integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
Band: 17q21.33
Quick LinksEntrez ID:3675; OMIM: 605025; Uniprot ID:ITA3_HUMAN; ENSEMBL ID: ENSG00000005884; HGNC ID: 6139
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
86N-linked (GlcNAc...) (Potential).
107N-linked (GlcNAc...) (Potential).
265N-linked (GlcNAc...) (Potential).
500N-linked (GlcNAc...) (Potential).
511N-linked (GlcNAc...) (Potential).
573N-linked (GlcNAc...) (Potential).
605N-linked (GlcNAc...) (Potential).
656N-linked (GlcNAc...) (Potential).
697N-linked (GlcNAc...) (Potential).
841N-linked (GlcNAc...) (Potential).
857N-linked (GlcNAc...) (Potential).
926N-linked (GlcNAc...) (Potential).
935N-linked (GlcNAc...) (Potential).
969N-linked (GlcNAc...) (Potential).
1021GFFKR motif.
Location(AA) Modifications Resource
86N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
107N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
265N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
500N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
511N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
573N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
605N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
656N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
697N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
841N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
857N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
926N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
935N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
969N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
86N-linkedHMM predict
92Phosphotyrosine(Jak)HMM predict
107N-linkedHMM predict
112N-linkedHMM predict
144Phosphotyrosine(Abl)HMM predict
173Phosphoserine(CK1)HMM predict
174Phosphoserine(ATM)HMM predict
174Phosphoserine(CK1)HMM predict
191Phosphotyrosine(Jak)HMM predict
191Phosphotyrosine(Syk)HMM predict
239SulfotyrosineHMM predict
239Phosphotyrosine(Syk)HMM predict
265N-linkedHMM predict
445Phosphotyrosine(Syk)HMM predict
445Phosphotyrosine(EGFR)HMM predict
511N-linkedHMM predict
528MethylarginineHMM predict
605N-linkedHMM predict
656N-linkedHMM predict
659N-linkedHMM predict
660O-linkedHMM predict
697N-linkedHMM predict
741Phosphoserine(CK1)HMM predict
841N-linkedHMM predict
857N-linkedHMM predict
869Phosphoserine(CDK)HMM predict
869Phosphoserine(CDC2)HMM predict
926N-linkedHMM predict
935N-linkedHMM predict
969N-linkedHMM predict
1042Phosphotyrosine(SRC)HMM predict
1042Phosphotyrosine(Syk)HMM predict
1057ThreonineHMM predict
1061Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002204
  • Location:chr17 45488729-45522842
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 45483140 45484275 1135 5022
CTCF G2GSE9613 45481914 45482135 221 6705
FOXA1 MCF7GSE15244 45484575 45484910 335 3987
Fos K562GSE19551 45483208 45483861 653 5195
H3K4me2 HCT116GSE10453 45482673 45483021 348 5883
P300 T30-glioblastomaGSE21026 45482961 45484240 1279 5129
RARG MCF7GSE15244 45487728 45488011 283 860
Rb GrowingGSE19898 45469851 45470016 165 18796
Rb GrowingGSE19898 45470074 45470181 107 18602
Rb SenescentGSE19898 45487513 45488191 678 878
TFAP2C MCF7GSE21234 45483251 45483936 685 5136
p130 SenescentGSE19898 45469821 45470431 610 18604
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 45523323 45523720 397 679
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 45519848 45520202 354 0
CTCF CD4SISSRdata 45519848 45520202 354 0
CTCF HelaGSE12889 45519743 45520140 397 0
CTCF JurkatGSE12889 45512029 45512277 248 0
CTCF JurkatGSE12889 45519711 45520170 459 0
CTCF G2GSE9613 45488546 45489181 635 0
CTCF G2GSE9613 45512136 45512622 486 0
CTCF G2GSE9613 45519891 45520885 994 0
H3K4me2 HCT116GSE10453 45490923 45491146 223 0
Rb QuiescentGSE19898 45488916 45489156 240 0
Rb QuiescentGSE19898 45489502 45489715 213 0
Rb shRbQuiescentGSE19898 45489484 45489660 176 0
TAFII hESGSE17917 45519857 45520143 286 0
TFAP2C MCF7GSE21234 45494629 45495321 692 0
TFAP2C MCF7GSE21234 45496954 45497438 484 0
TFAP2C MCF7GSE21234 45512091 45512930 839 0
hScc1 BcellGSE12603 45519891 45520449 558 0
hScc1 CdLSGSE12603 45519891 45520143 252 0
p130 shRbQuiescentGSE19898 45488921 45489447 526 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 19229884
hsa-miR-1 hsa-mir-1-1 20 19229884
hsa-miR-142-3p hsa-mir-142 17 19229884
hsa-miR-331-3p hsa-mir-331 12 19229884
hsa-miR-331-5p hsa-mir-331 12 19229884
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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