AutismKB 2.0

Annotation Detail for ITGAX


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Basic Information Top
Gene Symbol:ITGAX ( CD11C,SLEB6 )
Gene Full Name: integrin, alpha X (complement component 3 receptor 4 subunit)
Band: 16p11.2
Quick LinksEntrez ID:3687; OMIM: 151510; Uniprot ID:ITAX_HUMAN; ENSEMBL ID: ENSG00000140678; HGNC ID: 6152
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
61N-linked (GlcNAc...) (Potential).
89N-linked (GlcNAc...) (Potential).
392N-linked (GlcNAc...) (Potential).
697N-linked (GlcNAc...) (Potential).
735N-linked (GlcNAc...) (Potential).
899N-linked (GlcNAc...).
939N-linked (GlcNAc...) (Potential).
1050N-linked (GlcNAc...) (Potential).
1135GFFKR motif.
Location(AA) Modifications Resource
61N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
89N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
392N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
697N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
735N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
899N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
939N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1050N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
61N-linkedHMM predict
67Phosphotyrosine(INSR)HMM predict
98O-linkedHMM predict
99O-linkedHMM predict
101Phosphoserine(IKK)HMM predict
210Phosphoserine(IKK)HMM predict
269Phosphotyrosine(Syk)HMM predict
309Phosphoserine(CK1)HMM predict
309Phosphoserine(ATM)HMM predict
341O-linkedHMM predict
346O-linkedHMM predict
385N-linkedHMM predict
387Phosphoserine(CDC2)HMM predict
392N-linkedHMM predict
397N-linkedHMM predict
403Phosphoserine(PKG)HMM predict
437PhosphothreonineHMM predict
565PhosphoserineHMM predict
565Phosphoserine(ATM)HMM predict
565O-linkedHMM predict
569Phosphoserine(ATM)HMM predict
589Phosphoserine(ATM)HMM predict
687Phosphoserine(CDC2)HMM predict
697N-linkedHMM predict
699PhosphoserineHMM predict
701PhosphoserineHMM predict
735N-linkedHMM predict
815Phosphotyrosine(EGFR)HMM predict
818O-linkedHMM predict
820O-linkedHMM predict
899N-linkedHMM predict
904N-linkedHMM predict
905N-linkedHMM predict
906Phosphothreonine(MAPK)HMM predict
939N-linkedHMM predict
943Phosphoserine(CK2)HMM predict
943PhosphoserineHMM predict
1104N-linkedHMM predict
1149AlanineHMM predict
1152N-linkedHMM predict
1156Phosphothreonine(CDC2)HMM predict
1156Phosphothreonine(MAPK)HMM predict
1158Phosphoserine(CDC2)HMM predict
1158Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000887
  • Location:chr16 31274009-31301818
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
RARA MCF7GSE15244 31304265 31304695 430 2662
RARA MCF7GSE15244 31305053 31305394 341 3405
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 31301496 31301657 161 0
CTCF CD4SISSRdata 31301496 31301657 161 0
CTCF JurkatGSE12889 31301512 31301676 164 0
CTCF G2GSE9613 31274762 31275071 309 0
CTCF G2GSE9613 31280234 31280512 278 0
Oct4 hESGSE17917 31280958 31281301 343 0
Rb GrowingGSE19898 31274698 31274873 175 0
TFAP2C MCF7GSE21234 31301366 31301829 463 0
hScc1 BcellGSE12603 31301292 31301804 512 0
hScc1 CdLSGSE12603 31300996 31301727 731 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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