Annotation Detail for ITGB2
Basic Information Top
| Gene Symbol: | ITGB2 ( CD18,LAD,LCAMB,LFA-1,MAC-1,MF17,MFI7 ) |
|---|---|
| Gene Full Name: | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| Band: | 21q22.3 |
| Quick Links | Entrez ID:3689; OMIM: 600065; Uniprot ID:ITB2_HUMAN; ENSEMBL ID: ENSG00000160255; HGNC ID: 6155 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 23 | Pyrrolidone carboxylic acid. | |
| 50 | N-linked (GlcNAc...). | |
| 116 | N-linked (GlcNAc...). | |
| 212 | N-linked (GlcNAc...). | |
| 213 | N-linked (GlcNAc...). | |
| 215 | N-linked (GlcNAc...). | |
| 254 | N-linked (GlcNAc...) (Potential). | |
| 399 | Cell attachment site (Potential). | |
| 501 | N-linked (GlcNAc...) (Potential). | |
| 642 | N-linked (GlcNAc...) (Potential). | |
| 745 | Phosphoserine; by PKC. | |
| 756 | Phosphoserine. | |
| 758 | Phosphothreonine; by PKC; in vitro. | |
| 759 | Phosphothreonine (Potential). | |
| 760 | Phosphothreonine; by PKC/PRKCA; in vitro. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 23 | Pyrrolidone carboxylic acid. | Swiss-Prot 53.0 |
| 50 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 116 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 212 | N-linked (GlcNAc...). | Swiss-Prot 53.0 |
| 254 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 501 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 642 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 745 | Phosphoserine (by PKC). | Swiss-Prot 53.0 |
| 745 | Phosphoserine (PKC alpha;PK) | Phospho.ELM 6.0 |
| 756 | Phosphoserine (PKC | |
| 756 | Phosphoserine. | Swiss-Prot 53.0 |
| 758 | Phosphothreonine; by PKC; in vitro. | Swiss-Prot 53.0 |
| 758 | Phosphothreonine (PKC alpha;PK) | Phospho.ELM 6.0 |
| 759 | Phosphothreonine (Potential). | Swiss-Prot 53.0 |
| 759 | Phosphothreonine | Phospho.ELM 6.0 |
| 760 | Phosphothreonine; by PKC/PRKCA; in vitro. | Swiss-Prot 53.0 |
| 760 | Phosphothreonine (PKC |
| Location(AA) | Modification | Resource |
|---|---|---|
| 43 | S-palmitoyl | HMM predict |
| 50 | N-linked | HMM predict |
| 83 | Phosphoserine(IKK) | HMM predict |
| 99 | Phosphoserine(CDK) | HMM predict |
| 99 | Phosphoserine(CDC2) | HMM predict |
| 116 | N-linked | HMM predict |
| 212 | N-linked | HMM predict |
| 213 | N-linked | HMM predict |
| 215 | N-linked | HMM predict |
| 254 | N-linked | HMM predict |
| 349 | Phosphoserine(CK1) | HMM predict |
| 490 | Phosphoserine(ATM) | HMM predict |
| 564 | S-palmitoyl | HMM predict |
| 620 | Phosphoserine(CDC2) | HMM predict |
| 620 | Phosphoserine(IKK) | HMM predict |
| 735 | Phosphotyrosine(EGFR) | HMM predict |
- RefSeq ID: NM_000211
- Location:chr21 45130298-45165302
- strand:-
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| H3K27me3 | colorectal | cancer | 45168860 | 45169455 | 595 | 3855 |
| NFkBII | GM10847 | GSE19485 | 45164906 | 45165917 | 1011 | 109 |
| hScc1 | Bcell | GSE12603 | 45170654 | 45171314 | 660 | 5682 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| H3ac | HepG2 | E | 45126263 | 45126615 | 352 | 3860 |
| H3ac | HepG2 | E | 45128872 | 45130057 | 1185 | 834 |
| Rb | shRbSenescence | GSE19898 | 45128701 | 45128949 | 248 | 1474 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CBP | Jurkat | GSE17954 | 45154526 | 45159383 | 4857 | 0 |
| CTCF | CD4 | GSE12889 | 45137165 | 45137518 | 353 | 0 |
| CTCF | CD4 | GSE12889 | 45156059 | 45156270 | 211 | 0 |
| CTCF | CD4 | SISSRdata | 45137165 | 45137518 | 353 | 0 |
| CTCF | CD4 | SISSRdata | 45156059 | 45156270 | 211 | 0 |
| CTCF | Jurkat | GSE12889 | 45137078 | 45137372 | 294 | 0 |
| CTCF | G2 | GSE9613 | 45133114 | 45133722 | 608 | 0 |
| CTCF | G2 | GSE9613 | 45137009 | 45137428 | 419 | 0 |
| CTCF | G2 | GSE9613 | 45155748 | 45156186 | 438 | 0 |
| ER | MCF7 | GSE19013 | 45147573 | 45148024 | 451 | 0 |
| ER | MCF7 | GSE19013 | 45150006 | 45150467 | 461 | 0 |
| FOXA1 | MCF7 | GSE15244 | 45161275 | 45161819 | 544 | 0 |
| H3ac | HepG2 | E | 45150244 | 45150432 | 188 | 0 |
| RARA | MCF7 | GSE15244 | 45155712 | 45155934 | 222 | 0 |
| RARG | MCF7 | GSE15244 | 45161275 | 45161819 | 544 | 0 |
| STAT1 | IFN | SISSRdata | 45136975 | 45137545 | 570 | 0 |
| TFAP2C | MCF7 | GSE21234 | 45141841 | 45142590 | 749 | 0 |
| TFAP2C | MCF7 | GSE21234 | 45145655 | 45146426 | 771 | 0 |
| TFAP2C | MCF7 | GSE21234 | 45149938 | 45150453 | 515 | 0 |
| TFAP2C | MCF7 | GSE21234 | 45155385 | 45156872 | 1487 | 0 |
| TFAP2C | MCF7 | GSE21234 | 45158065 | 45158883 | 818 | 0 |
| TFAP2C | MCF7 | GSE21234 | 45161878 | 45163397 | 1519 | 0 |
| hScc1 | Bcell | GSE12603 | 45130974 | 45131450 | 476 | 0 |
| hScc1 | Bcell | GSE12603 | 45132961 | 45133973 | 1012 | 0 |
| hScc1 | Bcell | GSE12603 | 45136091 | 45136522 | 431 | 0 |
| hScc1 | Bcell | GSE12603 | 45137009 | 45137601 | 592 | 0 |
| hScc1 | Bcell | GSE12603 | 45143716 | 45144284 | 568 | 0 |
| hScc1 | Bcell | GSE12603 | 45147674 | 45148595 | 921 | 0 |
| hScc1 | Bcell | GSE12603 | 45155934 | 45156207 | 273 | 0 |
| hScc1 | Bcell | GSE12603 | 45163807 | 45164236 | 429 | 0 |
| hScc1 | Bcell | GSE12603 | 45164473 | 45165181 | 708 | 0 |
| hScc1 | CdLS | GSE12603 | 45136971 | 45137565 | 594 | 0 |
Validated miRNA targets| Cluster ID | Plue Type | Plus Gene Name | Plus Chromosome | Plus Start | Plus End | Overlap Length | Minus Type | Minus Gene Name | Minus Chromosome | Minus Star | Minus End | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 17043 | mRNA | chr21 | 45165393 | 45174016 | 185 | mRNA | ITGB2 | chr21 | 45130333 | 45173181 | Sense/Antisense (SA) pairs | |