AutismKB 2.0

Annotation Detail for ARAF


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Basic Information Top
Gene Symbol:ARAF ( A-RAF,ARAF1,PKS2,RAFA1 )
Gene Full Name: v-raf murine sarcoma 3611 viral oncogene homolog
Band: Xp11.3
Quick LinksEntrez ID:369; OMIM: 311010; Uniprot ID:ARAF_HUMAN; ENSEMBL ID: ENSG00000078061; HGNC ID: 646
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
186Phosphoserine.
213Phosphothreonine.
215Phosphothreonine.
257Phosphoserine.
318Phosphothreonine.
580Phosphoserine.
582Phosphoserine.
Location(AA) Modifications Resource
186PhosphoserinePhospho.ELM 6.0
257Phosphoserine.Swiss-Prot 53.0
299PhosphoserinePhospho.ELM 6.0
301Phosphotyrosine (Src)Phospho.ELM 6.0
302Phosphotyrosine (Src)Phospho.ELM 6.0
582Phosphoserine.Swiss-Prot 53.0
582PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
112S-palmitoylHMM predict
128S-palmitoylHMM predict
186Phosphoserine(CDC2)HMM predict
186O-linkedHMM predict
214Phosphoserine(PKB)HMM predict
247MethylarginineHMM predict
253Phosphothreonine(CDC2)HMM predict
257PhosphoserineHMM predict
257Phosphoserine(CDC2)HMM predict
257O-linkedHMM predict
259Phosphoserine(CDC2)HMM predict
259O-linkedHMM predict
262Phosphoserine(IKK)HMM predict
264O-linkedHMM predict
269Phosphoserine(CDK)HMM predict
269Phosphoserine(CDC2)HMM predict
274Phosphoserine(IKK)HMM predict
274Phosphoserine(CDC2)HMM predict
282MethyllysineHMM predict
419Phosphotyrosine(Jak)HMM predict
458Phosphoserine(IKK)HMM predict
469Phosphoserine(ATM)HMM predict
493Phosphotyrosine(Abl)HMM predict
509Phosphotyrosine(Jak)HMM predict
526Phosphotyrosine(Jak)HMM predict
532Phosphoserine(CK1)HMM predict
582Phosphoserine(CK1)HMM predict
582Phosphoserine(PKA)HMM predict
582Phosphoserine(CAMK2)HMM predict
582Phosphoserine(IKK)HMM predict
585Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001654
  • Location:chrX 47305450-47316242
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 47285350 47285833 483 19859
ER Fulvestrant-MCF7GSE14664 47299887 47299924 37 5545
Fos K562GSE19551 47300329 47300979 650 4797
Myc K562GSE19551 47285472 47285847 375 19791
Oct1 HelaGSE14283 47299883 47299965 82 5527
Oct1 HelaGSE14283 47300060 47300088 28 5377
Oct4 hESGSE17917 47300487 47300934 447 4740
PolII HeLaGSE12783 47285305 47286217 912 19690
hScc1 BcellGSE12603 47304876 47305193 317 416
hScc1 G2GSE9613 47285350 47285868 518 19842
hScc1 G2GSE9613 47304876 47305167 291 429
p130 SenescentGSE19898 47300452 47300857 405 4796
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 47313368 47313525 157 0
CTCF CD4SISSRdata 47313368 47313525 157 0
CTCF G2GSE9613 47305411 47305944 533 0
CTCF G2GSE9613 47306861 47307519 658 0
CTCF G2GSE9613 47311179 47311737 558 0
CTCF G2GSE9613 47313803 47314245 442 0
CTCF G2GSE9613 47315297 47315852 555 0
Fos K562GSE19551 47305123 47305945 822 0
PHF8 HeLaGSE20725 47305053 47306129 1076 0
hScc1 CdLSGSE12603 47306861 47307404 543 0
hScc1 G2GSE9613 47305485 47306016 531 0
hScc1 G2GSE9613 47306935 47307762 827 0
hScc1 G2GSE9613 47311102 47311445 343 0
hScc1 G2GSE9613 47315414 47315809 395 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 15685193
hsa-miR-1 hsa-mir-1-1 20 15685193
hsa-miR-124 hsa-mir-124-1 8 15685193
hsa-miR-124 hsa-mir-124-2 8 15685193
hsa-miR-124 hsa-mir-124-3 20 15685193
hsa-miR-373 hsa-mir-373 19 15685193
hsa-miR-373* hsa-mir-373 19 15685193
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
27585 mRNA ARAF chrX 47176872 47187573 20 EST chrX 47187553 47187918Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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