AutismKB 2.0

Annotation Detail for ITPKA


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Basic Information Top
Gene Symbol:ITPKA ( IP3-3KA,IP3KA )
Gene Full Name: inositol 1,4,5-trisphosphate 3-kinase A
Band: 15q15.1
Quick LinksEntrez ID:3706; OMIM: 147521; Uniprot ID:IP3KA_HUMAN; ENSEMBL ID: ENSG00000137825; HGNC ID: 6178
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
20Phosphoserine(MAPK)HMM predict
95Phosphoserine(MAPK)HMM predict
95O-linkedHMM predict
95Phosphoserine(CDK)HMM predict
95Phosphoserine(CDC2)HMM predict
111Phosphoserine(PKC)HMM predict
121Phosphoserine(PKG)HMM predict
121Phosphoserine(PKC)HMM predict
121Phosphoserine(PKA)HMM predict
121Phosphoserine(CK1)HMM predict
122Phosphothreonine(PKA)HMM predict
122Phosphothreonine(PKG)HMM predict
123Phosphoserine(IKK)HMM predict
123O-linkedHMM predict
124Phosphoserine(IKK)HMM predict
128O-linkedHMM predict
132Phosphoserine(CK2)HMM predict
143Phosphoserine(CK2)HMM predict
143Phosphoserine(CK1)HMM predict
147Phosphoserine(CK1)HMM predict
180Phosphoserine(CDC2)HMM predict
301PhosphothreonineHMM predict
311Phosphothreonine(PKC)HMM predict
341Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002220
  • Location:chr15 39573413-39583036
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 39569590 39570383 793 3427
Fos K562GSE19551 39569793 39570307 514 3364
H3ac HepG2E 39570955 39571555 600 2159
NFkBII GM12892GSE19485 39572350 39573865 1515 306
Oct1 H2O2-HelaGSE14283 39572183 39572222 39 1211
Oct1 HelaGSE14283 39572182 39572228 46 1209
Rb GrowingGSE19898 39572322 39572565 243 970
Rb GrowingGSE19898 39572601 39572746 145 740
Rb GrowingGSE19898 39572825 39573095 270 454
Rb SenescentGSE19898 39572566 39573459 893 401
Rb shRbSenescenceGSE19898 39572864 39573208 344 378
hScc1 BcellGSE12603 39572646 39573862 1216 160
p130 SenescentGSE19898 39572189 39573286 1097 676
p130 shRbSenescentGSE19898 39572294 39572525 231 1004
p130 shRbSenescentGSE19898 39572733 39573346 613 374
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 39574805 39575304 499 0
CTCF G2GSE9613 39582444 39582648 204 0
H3ac HepG2E 39576037 39576401 364 0
hScc1 BcellGSE12603 39574337 39574566 229 0
hScc1 BcellGSE12603 39575518 39576037 519 0
p130 shRbSenescentGSE19898 39581091 39581359 268 0
Validated miRNA targets Top
Cis-Nats regulation Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018