Annotation Detail for JAK3
Basic Information Top
| Gene Symbol: | JAK3 ( JAK-3,JAK3_HUMAN,JAKL,L-JAK,LJAK ) |
|---|---|
| Gene Full Name: | Janus kinase 3 |
| Band: | 19p13.11 |
| Quick Links | Entrez ID:3718; OMIM: 600173; Uniprot ID:JAK3_HUMAN; ENSEMBL ID: ENSG00000105639; HGNC ID: 6193 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 8 | Phosphothreonine (By similarity). | |
| 783 | Phosphoserine. | |
| 785 | Phosphotyrosine. | |
| 980 | Phosphotyrosine; by autocatalysis. | |
| 981 | Phosphotyrosine; by autocatalysis. | |
| 1027 | Phosphoserine (By similarity). | |
| 1031 | Phosphoserine (By similarity). | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 785 | Phosphotyrosine. | Swiss-Prot 53.0 |
| 785 | Phosphotyrosine (JAK3) | Phospho.ELM 6.0 |
| 980 | Phosphotyrosine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 |
| 980 | Phosphotyrosine (JAK3) | Phospho.ELM 6.0 |
| 981 | Phosphotyrosine (JAK3) | Phospho.ELM 6.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 147 | O-linked | HMM predict |
| 216 | Phosphothreonine(PKC) | HMM predict |
| 319 | Phosphothreonine(PKC) | HMM predict |
| 433 | Phosphoserine(CDC2) | HMM predict |
| 435 | Phosphothreonine(PKA) | HMM predict |
| 474 | S-palmitoyl | HMM predict |
| 475 | S-palmitoyl | HMM predict |
| 493 | Phosphoserine(ATM) | HMM predict |
| 493 | Phosphoserine(IKK) | HMM predict |
| 498 | O-linked | HMM predict |
| 498 | O-linked | HMM predict |
| 509 | Phosphoserine(ATM) | HMM predict |
| 720 | O-linked | HMM predict |
| 980 | Phosphotyrosine(Syk) | HMM predict |
| 980 | Phosphotyrosine | HMM predict |
| 980 | Phosphotyrosine(Jak) | HMM predict |
| 981 | Phosphotyrosine(Jak) | HMM predict |
| 981 | Phosphotyrosine(Syk) | HMM predict |
| 981 | Phosphotyrosine(Jak) | HMM predict |
| 1024 | S-palmitoyl | HMM predict |
| 1029 | Phosphoserine(MAPK) | HMM predict |
- RefSeq ID: NM_000215
- Location:chr19 17797960-17819799
- strand:-
| No data |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| H3K27me3 | colorectal | cancer | 17817936 | 17818332 | 396 | 0 |
| KLF4 | hES | GSE17917 | 17802349 | 17802582 | 233 | 0 |
| KLF4 | hES | GSE17917 | 17813742 | 17814000 | 258 | 0 |
| NFkBII | GM12892 | GSE19485 | 17819068 | 17820327 | 1259 | 0 |
| NFkBII | GM15510 | GSE19485 | 17818989 | 17820448 | 1459 | 0 |
| hScc1 | Bcell | GSE12603 | 17813742 | 17814213 | 471 | 0 |
| hScc1 | Bcell | GSE12603 | 17819363 | 17819805 | 442 | 0 |
| p130 | Senescent | GSE19898 | 17819525 | 17819894 | 369 | 0 |
| p130 | shRbSenescent | GSE19898 | 17819587 | 17819998 | 411 | 0 |
Cis-Nats regulation