AutismKB 2.0

Annotation Detail for JUN


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Basic Information Top
Gene Symbol:JUN ( AP-1,AP1,c-Jun )
Gene Full Name: jun proto-oncogene
Band: 1p32.1
Quick LinksEntrez ID:3725; OMIM: 165160; Uniprot ID:JUN_HUMAN; ENSEMBL ID: ENSG00000177606; HGNC ID: 6204
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
58Phosphoserine.
62Phosphothreonine.
63Phosphoserine; by MAPK8.
73Phosphoserine; by MAPK8.
239Phosphothreonine.
243Phosphoserine.
249Phosphoserine.
Location(AA) Modifications Resource
63Phosphoserine (by MAPK8).Swiss-Prot 53.0
63Phosphoserine (CK2
73Phosphoserine (by MAPK8).Swiss-Prot 53.0
73Phosphoserine (CK2
91PhosphothreoninePhospho.ELM 6.0
93PhosphothreoninePhospho.ELM 6.0
170Phosphotyrosine (Abl)Phospho.ELM 6.0
231Phosphothreonine (CK2
239Phosphothreonine (GSK-3
243Phosphoserine (ERT PK;CK2 a)Phospho.ELM 6.0
249Phosphoserine (CK2
Location(AA) Modification Resource
10SulfotyrosineHMM predict
10Phosphotyrosine(Syk)HMM predict
28Phosphotyrosine(INSR)HMM predict
63Phosphoserine(CDK)HMM predict
63Phosphoserine(MAPK)HMM predict
73Phosphoserine(MAPK)HMM predict
91O-linkedHMM predict
93Phosphothreonine(MAPK)HMM predict
95O-linkedHMM predict
95O-linkedHMM predict
102N-linkedHMM predict
123Phosphoserine(ATM)HMM predict
129O-linkedHMM predict
131O-linkedHMM predict
132O-linkedHMM predict
170Phosphotyrosine(INSR)HMM predict
172N-linkedHMM predict
175N-linkedHMM predict
177N-linkedHMM predict
239PhosphothreonineHMM predict
249Phosphoserine(ATM)HMM predict
267Phosphoserine(PKC)HMM predict
286Phosphothreonine(PKC)HMM predict
316ValineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002228
  • Location:chr1 59019052-59022372
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 59023189 59023616 427 1030
FOXA1 MCF7GSE15244 59022984 59024314 1330 1277
H3ac HepG2E 59023144 59023616 472 1008
Myc hESGSE17917 59022576 59022848 272 340
Oct1 H2O2-HelaGSE14283 59028416 59028451 35 6061
Oct1 HelaGSE14283 59026090 59026137 47 3741
Oct1 HelaGSE14283 59030903 59030942 39 8550
PHF8 293TGSE20725 59021770 59023752 1982 389
RARA MCF7GSE15244 59023144 59024374 1230 1387
TFAP2C MCF7GSE21234 59023177 59024397 1220 1415
hScc1 BcellGSE12603 59023144 59023558 414 979
hScc1 CdLSGSE12603 59023020 59024279 1259 1277
p63 keratinocytesGSE17611 59032569 59033393 824 10609
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 59007356 59007889 533 11430
Oct1 HelaGSE14283 59004081 59004112 31 14956
Oct1 HelaGSE14283 59004387 59004470 83 14624
SRF HelaGSE8489 59016147 59019359 3212 1300
hScc1 BcellGSE12603 59007464 59007889 425 11376
hScc1 CdLSGSE12603 59007430 59007889 459 11393
hScc1 G2GSE9613 59007287 59007922 635 11448
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 59020680 59021242 562 0
CTCF G2GSE9613 59022051 59022473 422 0
LIN9 SGSE7516 59021345 59022018 673 0
Pol2 GM12878GSE19551 59019912 59023948 4036 0
hScc1 BcellGSE12603 59020394 59021802 1408 0
hScc1 BcellGSE12603 59022128 59022494 366 0
hScc1 CdLSGSE12603 59020027 59022749 2722 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 19396864
hsa-let-7b* hsa-let-7b 22 18668040
hsa-let-7e* hsa-let-7e 19 19396864
hsa-miR-1 hsa-mir-1-2 18 19074548
hsa-miR-1 hsa-mir-1-1 20 19074548
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-100 hsa-mir-100 11 19074548
hsa-miR-100* hsa-mir-100 11 19074548
hsa-miR-106b hsa-mir-106b 7 19074548
hsa-miR-106b* hsa-mir-106b 7 19074548
hsa-miR-1228* hsa-mir-1228 12 19396864
hsa-miR-125a-3p hsa-mir-125a 19 19074548
hsa-miR-125a-5p hsa-mir-125a 19 19074548
hsa-miR-125b hsa-mir-125b-1 11 21368288
hsa-miR-125b hsa-mir-125b-2 21 21368288
hsa-miR-125b hsa-mir-125b-1 11 19074548
hsa-miR-125b hsa-mir-125b-2 21 19074548
hsa-miR-126 hsa-mir-126 9 19074548
hsa-miR-126* hsa-mir-126 9 19074548
hsa-miR-127-3p hsa-mir-127 14 19396864
hsa-miR-141 hsa-mir-141 12 19861690
hsa-miR-141 hsa-mir-141 12 19074548
hsa-miR-141* hsa-mir-141 12 19861690
hsa-miR-141* hsa-mir-141 12 19074548
hsa-miR-142-3p hsa-mir-142 17 19074548
hsa-miR-143 hsa-mir-143 5 19074548
hsa-miR-143* hsa-mir-143 5 19074548
hsa-miR-144* hsa-mir-144 17 19396864
hsa-miR-145 hsa-mir-145 5 19074548
hsa-miR-145* hsa-mir-145 5 19074548
hsa-miR-146a hsa-mir-146a 5 19635561
hsa-miR-146a* hsa-mir-146a 5 19635561
hsa-miR-146b-3p hsa-mir-146b 10 19635561
hsa-miR-146b-5p hsa-mir-146b 10 19635561
hsa-miR-150 hsa-mir-150 19 19074548
hsa-miR-150* hsa-mir-150 19 19074548
hsa-miR-155 hsa-mir-155 21 20871480
hsa-miR-155 hsa-mir-155 21 20852130
hsa-miR-155 hsa-mir-155 21 18940871
hsa-miR-155 hsa-mir-155 21 18048365
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 20871480
hsa-miR-155* hsa-mir-155 21 20852130
hsa-miR-155* hsa-mir-155 21 18940871
hsa-miR-155* hsa-mir-155 21 18048365
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-15a hsa-mir-15a 13 18362358
hsa-miR-15a* hsa-mir-15a 13 18362358
hsa-miR-15b hsa-mir-15b 3 19861690
hsa-miR-15b* hsa-mir-15b 3 19861690
hsa-miR-16 hsa-mir-16-1 13 18362358
hsa-miR-16 hsa-mir-16-2 3 18362358
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-16-1* hsa-mir-16-1 13 18362358
hsa-miR-194 hsa-mir-194-1 1 19074548
hsa-miR-194 hsa-mir-194-2 11 19074548
hsa-miR-195 hsa-mir-195 17 20952681
hsa-miR-195* hsa-mir-195 17 20952681
hsa-miR-195* hsa-mir-195 17 19396864
hsa-miR-196b hsa-mir-196b 7 19074548
hsa-miR-198 hsa-mir-198 0 17849003
hsa-miR-200a hsa-mir-200a 1 19074548
hsa-miR-200a* hsa-mir-200a 1 19074548
hsa-miR-200b hsa-mir-200b 1 20498046
hsa-miR-200b hsa-mir-200b 1 19074548
hsa-miR-200b* hsa-mir-200b 1 20498046
hsa-miR-200b* hsa-mir-200b 1 19074548
hsa-miR-203 hsa-mir-203 14 19759552
hsa-miR-203 hsa-mir-203 14 19396864
hsa-miR-206 hsa-mir-206 6 17849003
hsa-miR-20a hsa-mir-20a 13 19074548
hsa-miR-20a* hsa-mir-20a 13 19074548
hsa-miR-21 hsa-mir-21 17 21141738
hsa-miR-21 hsa-mir-21 17 19308091
hsa-miR-21 hsa-mir-21 17 18384814
hsa-miR-21* hsa-mir-21 17 21141738
hsa-miR-21* hsa-mir-21 17 19308091
hsa-miR-21* hsa-mir-21 17 18384814
hsa-miR-214 hsa-mir-214 1 20498046
hsa-miR-214* hsa-mir-214 1 20498046
hsa-miR-223 hsa-mir-223 X 20826802
hsa-miR-223 hsa-mir-223 X 19074548
hsa-miR-223* hsa-mir-223 X 20826802
hsa-miR-223* hsa-mir-223 X 19074548
hsa-miR-24 hsa-mir-24-1 9 19861690
hsa-miR-24 hsa-mir-24-2 19 19861690
hsa-miR-25 hsa-mir-25 7 19861690
hsa-miR-25* hsa-mir-25 7 19861690
hsa-miR-26a hsa-mir-26a-1 3 20080666
hsa-miR-26a hsa-mir-26a-2 12 20080666
hsa-miR-299-3p hsa-mir-299 14 19396864
hsa-miR-29c hsa-mir-29c 1 19074548
hsa-miR-29c* hsa-mir-29c 1 19074548
hsa-miR-301a hsa-mir-301a 17 19396864
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 19396864
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
hsa-miR-32* hsa-mir-32 9 19396864
hsa-miR-340* hsa-mir-340 5 19396864
hsa-miR-345 hsa-mir-345 14 19396864
hsa-miR-34a* hsa-mir-34a 1 19396864
hsa-miR-34c-3p hsa-mir-34c 11 19074548
hsa-miR-34c-5p hsa-mir-34c 11 19074548
hsa-miR-365 hsa-mir-365-1 16 19074548
hsa-miR-365 hsa-mir-365-2 17 19074548
hsa-miR-379 hsa-mir-379 14 19396864
hsa-miR-379* hsa-mir-379 14 19396864
hsa-miR-410 hsa-mir-410 14 21170085
hsa-miR-423-3p hsa-mir-423 17 19396864
hsa-miR-423-5p hsa-mir-423 17 19396864
hsa-miR-424 hsa-mir-424 X 19074548
hsa-miR-424* hsa-mir-424 X 19074548
hsa-miR-455-3p hsa-mir-455 9 19396864
hsa-miR-483-3p hsa-mir-483 11 19396864
hsa-miR-494 hsa-mir-494 14 20878133
hsa-miR-582-3p hsa-mir-582 5 19396864
hsa-miR-582-5p hsa-mir-582 5 19396864
hsa-miR-584 hsa-mir-584 5 19396864
hsa-miR-595 hsa-mir-595 7 19396864
hsa-miR-615-3p hsa-mir-615 12 19396864
hsa-miR-650 hsa-mir-650 22 21170085
hsa-miR-7-1* hsa-mir-7-1 9 19396864
hsa-miR-885-3p hsa-mir-885 3 19396864
hsa-miR-9 hsa-mir-9-1 1 19396864
hsa-miR-9 hsa-mir-9-2 5 19396864
hsa-miR-9 hsa-mir-9-3 15 19396864
hsa-miR-99a hsa-mir-99a 21 19074548
hsa-miR-99a* hsa-mir-99a 21 19074548
hsa-miR-99b hsa-mir-99b 19 19074548
hsa-miR-99b* hsa-mir-99b 19 19074548
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1239 Unknown pSILAC miR-30 JUN down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000177606 n_a n_a n_a n_a n_a
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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