AutismKB 2.0

Annotation Detail for JUP


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Basic Information Top
Gene Symbol:JUP ( ARVD12,CTNNG,DP3,DPIII,PDGB,PKGB )
Gene Full Name: junction plakoglobin
Band: 17q21.2
Quick LinksEntrez ID:3728; OMIM: 173325; Uniprot ID:PLAK_HUMAN; ENSEMBL ID: ENSG00000173801; HGNC ID: 6207
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1N-acetylmethionine.
20Phosphotyrosine.
182Phosphoserine.
660Phosphotyrosine.
665Phosphoserine.
Location(AA) Modifications Resource
19PhosphotyrosinePhospho.ELM 6.0
20Phosphotyrosine.Swiss-Prot 53.0
181PhosphoserinePhospho.ELM 6.0
182Phosphoserine.Swiss-Prot 53.0
663PhosphoserinePhospho.ELM 6.0
664Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
36O-linkedHMM predict
54Phosphothreonine(PKC)HMM predict
58O-linkedHMM predict
62O-linkedHMM predict
68Phosphoserine(ATM)HMM predict
195N-linkedHMM predict
211N-linkedHMM predict
237Phosphoserine(CDC2)HMM predict
320N-linkedHMM predict
377N-linkedHMM predict
416N-linkedHMM predict
420N-linkedHMM predict
421N-linkedHMM predict
424N-linkedHMM predict
664Phosphoserine(PKA)HMM predict
723SulfotyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002230
  • Location:chr17 37164389-37196474
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 37199826 37200060 234 3469
CTCF G2GSE9613 37202494 37202768 274 6157
ER MCF7GSE19013 37202856 37203734 878 6821
Fos K562GSE19551 37196051 37197215 1164 159
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 37196163 37196309 146 0
CTCF CD4SISSRdata 37196163 37196309 146 0
CTCF G2GSE9613 37164872 37165083 211 0
CTCF G2GSE9613 37179341 37179660 319 0
CTCF G2GSE9613 37185450 37185822 372 0
CTCF G2GSE9613 37192106 37192323 217 0
CTCF G2GSE9613 37195670 37196598 928 0
Gata2 K562GSE18868 37193918 37194630 712 0
H3ac HepG2E 37193909 37194394 485 0
P300 T30-glioblastomaGSE21026 37186764 37188279 1515 0
RARG MCF7GSE15244 37182437 37183042 605 0
RARG MCF7GSE15244 37187238 37188020 782 0
Rb GrowingGSE19898 37195903 37196046 143 0
Rb QuiescentGSE19898 37183168 37183460 292 0
Rb SenescentGSE19898 37183076 37183402 326 0
TFAP2C MCF7GSE21234 37181505 37183970 2465 0
TFAP2C MCF7GSE21234 37193879 37194538 659 0
TFAP2C MCF7GSE21234 37195510 37196096 586 0
hScc1 BcellGSE12603 37180645 37180780 135 0
hScc1 BcellGSE12603 37191167 37191483 316 0
hScc1 BcellGSE12603 37192106 37192287 181 0
hScc1 BcellGSE12603 37196015 37196661 646 0
p130 shRbSenescentGSE19898 37183153 37183344 191 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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