AutismKB 2.0

Annotation Detail for KCNJ4


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Basic Information Top
Gene Symbol:KCNJ4 ( HIR,HIRK2,HRK1,IRK-3,IRK3,Kir2.3,MGC142066,MGC142068 )
Gene Full Name: potassium inwardly-rectifying channel, subfamily J, member 4
Band: 22q13.1
Quick LinksEntrez ID:3761; OMIM: 600504; Uniprot ID:IRK4_HUMAN; ENSEMBL ID: ENSG00000168135; HGNC ID: 6265
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
139Selectivity filter (By similarity).
445PDZ-binding (Potential).
Location(AA) Modifications Resource
53Phosphothreonine (PKC delta)Phospho.ELM 6.0
Location(AA) Modification Resource
79S-palmitoylHMM predict
184Phosphothreonine(PKC)HMM predict
234Phosphotyrosine(Jak)HMM predict
272SulfotyrosineHMM predict
329Phosphotyrosine(Syk)HMM predict
347S-palmitoylHMM predict
348S-palmitoylHMM predict
407Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004981
  • Location:chr22 37152280-37169978
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
USF1 HepG2E 37138458 37138859 401 13622
hScc1 BcellGSE12603 37143334 37143635 301 8796
p130 shRbSenescentGSE19898 37132695 37132974 279 19446
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 37152695 37153218 523 0
hScc1 BcellGSE12603 37157150 37157368 218 0
hScc1 BcellGSE12603 37169018 37169948 930 0
p130 QuiescentGSE19898 37167356 37167568 212 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018