AutismKB 2.0

Annotation Detail for KCNMA1


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Basic Information Top
Gene Symbol:KCNMA1 ( BKTM,DKFZp686K1437,KCa1.1,MGC71881,MaxiK,SAKCA,SLO,SLO-ALPHA,SLO1,bA205K10.1,mSLO1 )
Gene Full Name: potassium large conductance calcium-activated channel, subfamily M, alpha member 1
Band: 10q22.3
Quick LinksEntrez ID:3778; OMIM: 600150; Uniprot ID:KCMA1_HUMAN; ENSEMBL ID: ENSG00000156113; HGNC ID: 6284
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
355Selectivity for potassium.
569Phosphoserine.
763Phosphothreonine (By similarity).
765Phosphoserine (By similarity).
977Phosphoserine (By similarity).
978Phosphoserine (By similarity).
1025Calcium bowl.
1086Phosphotyrosine.
1088Phosphothreonine (By similarity).
Location(AA) Modifications Resource
763Phosphothreonine (By similarity).Swiss-Prot 53.0
765Phosphoserine (By similarity).Swiss-Prot 53.0
977Phosphoserine (By similarity).Swiss-Prot 53.0
978Phosphoserine (By similarity).Swiss-Prot 53.0
1088Phosphothreonine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
40Phosphoserine(CK1)HMM predict
58Phosphoserine(CK1)HMM predict
60Phosphoserine(IKK)HMM predict
60Phosphoserine(CK1)HMM predict
60Phosphoserine(ATM)HMM predict
118S-palmitoylHMM predict
119S-palmitoylHMM predict
121S-palmitoylHMM predict
133N-linkedHMM predict
136Phosphoserine(ATM)HMM predict
210Phosphotyrosine(Syk)HMM predict
265N-linkedHMM predict
765Phosphoserine(CDK)HMM predict
765Phosphoserine(CDC2)HMM predict
782PhosphoserineHMM predict
905Phosphothreonine(CDK)HMM predict
978Phosphoserine(IKK)HMM predict
982PhosphoserineHMM predict
982Phosphoserine(CDK)HMM predict
1007N-linkedHMM predict
1010N-linkedHMM predict
1069Phosphothreonine(MAPK)HMM predict
1088Phosphothreonine(CDK)HMM predict
1152O-linkedHMM predict
1188Phosphoserine(CK1)HMM predict
1192Phosphoserine(IKK)HMM predict
1196Phosphoserine(ATM)HMM predict
1205Phosphoserine(CK2)HMM predict
1205Phosphoserine(CK1)HMM predict
1208Phosphoserine(IKK)HMM predict
1208O-linkedHMM predict
1208Phosphoserine(CK1)HMM predict
1230Phosphotyrosine(EGFR)HMM predict
1230Phosphotyrosine(Jak)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002247
  • Location:chr10 78314641-79067582
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 79068688 79070158 1470 1841
Oct1 H2O2-HelaGSE14283 79076018 79076048 30 8451
hScc1 BcellGSE12603 79067822 79068368 546 513
hScc1 BcellGSE12603 79070984 79071852 868 3836
hScc1 BcellGSE12603 79073637 79074149 512 6311
hScc1 CdLSGSE12603 79071318 79071852 534 4003
hScc1 CdLSGSE12603 79073671 79074149 478 6328
hScc1 G2GSE9613 79067822 79068521 699 589
hScc1 G2GSE9613 79070984 79071852 868 3836
hScc1 G2GSE9613 79073671 79074258 587 6382
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 78693096 78695074 1978 0
CBP T30-glioblastomaGSE21026 78624511 78625489 978 0
CBP T30-glioblastomaGSE21026 78780035 78781791 1756 0
CBP T30-glioblastomaGSE21026 78785345 78786295 950 0
CTCF CD4GSE12889 78414595 78414985 390 0
CTCF CD4GSE12889 78434826 78435000 174 0
CTCF CD4GSE12889 78541685 78542049 364 0
CTCF CD4GSE12889 78595558 78595778 220 0
CTCF CD4GSE12889 78603678 78604046 368 0
CTCF CD4SISSRdata 78414595 78414985 390 0
CTCF CD4SISSRdata 78434826 78435000 174 0
CTCF CD4SISSRdata 78541685 78542049 364 0
CTCF CD4SISSRdata 78595558 78595778 220 0
CTCF CD4SISSRdata 78603678 78604046 368 0
CTCF HelaGSE12889 78414564 78414899 335 0
CTCF HelaGSE12889 78541740 78541954 214 0
CTCF HelaGSE12889 78603668 78603913 245 0
CTCF HelaGSE12889 79035367 79035567 200 0
ER E2-MCF7GSE14664 78421278 78421316 38 0
ER E2-MCF7GSE14664 78961412 78961451 39 0
ER Fulvestrant-MCF7GSE14664 78961401 78961445 44 0
ER MCF7GSE19013 78593776 78594293 517 0
ER MCF7GSE19013 78838721 78840634 1913 0
ER MCF7GSE19013 78880722 78881184 462 0
ER MCF7GSE19013 78891118 78891944 826 0
ER MCF7GSE19013 78909774 78910456 682 0
ER MCF7GSE19013 78937031 78937656 625 0
ER MCF7GSE19013 79012202 79013222 1020 0
ER MCF7GSE19013 79036377 79037021 644 0
FOXA1 MCF7GSE15244 78717367 78718124 757 0
FOXA1 MCF7GSE15244 78872139 78873297 1158 0
Fos K562GSE19551 78780389 78780780 391 0
Fos K562GSE19551 78835361 78835958 597 0
Fos K562GSE19551 79012461 79012993 532 0
FoxA1 MCF7MACSdata 78403769 78404049 280 0
FoxA1 MCF7MACSdata 79012429 79012789 360 0
H3K27me3 colorectalcancer 79064875 79066032 1157 0
Myc K562GSE19551 78595621 78595864 243 0
Myc K562GSE19551 78603754 78603928 174 0
Myc K562GSE19551 78961123 78961585 462 0
NFkBII GM12878GSE19485 78841903 78842972 1069 0
NFkBII GM12892GSE19485 78841624 78843008 1384 0
NFkBII GM12892GSE19485 78930038 78932403 2365 0
NRSF JurkatGSE13047 78757904 78758704 800 0
NRSF mAbJurkat 78752008 78752940 932 0
NRSF mAbJurkat 78753822 78757061 3239 0
NRSF mAbJurkat 78757435 78758544 1109 0
NRSF mAbJurkat 78759773 78760289 516 0
NRSF mAbJurkat 78760743 78761256 513 0
NRSF mAbJurkat 78761591 78764031 2440 0
NRSF-mono JurkatQuESTdata 78756591 78756934 343 0
NRSF-mono JurkatQuESTdata 78757903 78758703 800 0
NRSF-poly JurkatQuESTdata 78757867 78758711 844 0
Nanog ESGSE20650 78744074 78744623 549 0
Nanog ESGSE20650 78754771 78755259 488 0
Nanog hESGSE18292 78511322 78511736 414 0
Nanog hESGSE18292 78544173 78544799 626 0
Nanog hESGSE18292 78595584 78595804 220 0
Nanog hESGSE18292 78744130 78744648 518 0
Oct1 H2O2-HelaGSE14283 78416320 78416356 36 0
Oct1 H2O2-HelaGSE14283 78439328 78439360 32 0
Oct1 H2O2-HelaGSE14283 78496503 78496548 45 0
Oct1 H2O2-HelaGSE14283 78898454 78898482 28 0
Oct1 H2O2-HelaGSE14283 78900254 78900287 33 0
Oct1 H2O2-HelaGSE14283 78918532 78918562 30 0
Oct1 HelaGSE14283 78439328 78439360 32 0
Oct1 HelaGSE14283 78483189 78483228 39 0
Oct1 HelaGSE14283 78496503 78496557 54 0
Oct1 HelaGSE14283 78918532 78918561 29 0
Oct1 HelaGSE14283 78919302 78919338 36 0
Oct1 HelaGSE14283 78961413 78961454 41 0
Oct1 HelaGSE14283 78961927 78961960 33 0
Oct1 HelaGSE14283 79044988 79045095 107 0
P300 T30-glioblastomaGSE21026 78624545 78625416 871 0
P300 T30-glioblastomaGSE21026 78703674 78704445 771 0
P300 T30-glioblastomaGSE21026 78720214 78721134 920 0
P300 T30-glioblastomaGSE21026 78780005 78781918 1913 0
P300 T30-glioblastomaGSE21026 78785213 78786395 1182 0
P300 T30-glioblastomaGSE21026 78822222 78823098 876 0
P300 T30-glioblastomaGSE21026 78845796 78846924 1128 0
P300 T30-glioblastomaGSE21026 78994409 78995276 867 0
RARA MCF7GSE15244 78403331 78404165 834 0
RARA MCF7GSE15244 78541894 78542247 353 0
RARA MCF7GSE15244 78717186 78718088 902 0
RARA MCF7GSE15244 78839219 78840475 1256 0
RARA MCF7GSE15244 78909570 78910437 867 0
RARA MCF7GSE15244 78915263 78916310 1047 0
RARA MCF7GSE15244 78960964 78961921 957 0
RARA MCF7GSE15244 78962944 78964234 1290 0
RARA MCF7GSE15244 78994370 78994754 384 0
RARA MCF7GSE15244 79012366 79013279 913 0
RARA MCF7GSE15244 79036394 79037108 714 0
RARG MCF7GSE15244 78403475 78404128 653 0
RARG MCF7GSE15244 78717222 78718088 866 0
RARG MCF7GSE15244 78839897 78840440 543 0
RARG MCF7GSE15244 78880922 78881673 751 0
RARG MCF7GSE15244 78909287 78910405 1118 0
RARG MCF7GSE15244 78915335 78916310 975 0
RARG MCF7GSE15244 78960999 78962067 1068 0
RARG MCF7GSE15244 78963219 78963841 622 0
RARG MCF7GSE15244 78985597 78985777 180 0
RARG MCF7GSE15244 79012366 79013245 879 0
RARG MCF7GSE15244 79036394 79037108 714 0
RNAII Tamoxifen-MCF7GSE14664 78496506 78496550 44 0
RNAII Tamoxifen-MCF7GSE14664 78629372 78629411 39 0
Rb QuiescentGSE19898 78994933 78995123 190 0
Rb shRbQuiescentGSE19898 78814556 78814725 169 0
TFAP2C MCF7GSE21234 78403567 78403889 322 0
TFAP2C MCF7GSE21234 78593614 78594219 605 0
TFAP2C MCF7GSE21234 78822600 78823224 624 0
TFAP2C MCF7GSE21234 78839789 78840513 724 0
TFAP2C MCF7GSE21234 78915648 78916076 428 0
TFAP2C MCF7GSE21234 78961118 78961755 637 0
TFAP2C MCF7GSE21234 78963260 78964028 768 0
TFAP2C MCF7GSE21234 78977900 78978474 574 0
TFAP2C MCF7GSE21234 79012346 79012981 635 0
TFAP2C MCF7GSE21234 79018024 79018492 468 0
TFAP2C MCF7GSE21234 79034707 79035795 1088 0
TFAP2C MCF7GSE21234 79036425 79037097 672 0
VDR GM10861-stimGSE22484 78839418 78840706 1288 0
VDR GM10861-stimGSE22484 78920766 78922333 1567 0
c MYCMCF7 78949570 78950311 741 0
hScc1 BcellGSE12603 78332389 78332843 454 0
hScc1 BcellGSE12603 78514055 78514338 283 0
hScc1 BcellGSE12603 78541319 78541972 653 0
hScc1 BcellGSE12603 78595471 78596059 588 0
hScc1 BcellGSE12603 78603462 78604159 697 0
hScc1 BcellGSE12603 78643798 78644162 364 0
hScc1 BcellGSE12603 78801026 78801206 180 0
hScc1 BcellGSE12603 78817063 78817266 203 0
hScc1 BcellGSE12603 78821598 78821831 233 0
hScc1 BcellGSE12603 78873125 78873297 172 0
hScc1 BcellGSE12603 78927774 78928311 537 0
hScc1 BcellGSE12603 78945535 78945895 360 0
hScc1 BcellGSE12603 78959655 78959924 269 0
hScc1 BcellGSE12603 79033296 79033529 233 0
hScc1 BcellGSE12603 79066507 79066882 375 0
hScc1 CdLSGSE12603 78541502 78542283 781 0
hScc1 CdLSGSE12603 78595431 78596194 763 0
hScc1 CdLSGSE12603 78603498 78604159 661 0
hScc1 CdLSGSE12603 78681000 78681388 388 0
hScc1 CdLSGSE12603 78821526 78821831 305 0
hScc1 G2GSE9613 78332666 78333080 414 0
hScc1 G2GSE9613 78541502 78542147 645 0
hScc1 G2GSE9613 78595431 78596161 730 0
hScc1 G2GSE9613 78603384 78604089 705 0
hScc1 G2GSE9613 78680897 78681388 491 0
hScc1 G2GSE9613 78995525 78995849 324 0
p130 QuiescentGSE19898 78608722 78609047 325 0
p130 QuiescentGSE19898 78787820 78787998 178 0
p130 QuiescentGSE19898 79012687 79012918 231 0
p130 QuiescentGSE19898 79013026 79013136 110 0
p130 SenescentGSE19898 78814393 78814724 331 0
p130 SenescentGSE19898 78931046 78931409 363 0
p63 keratinocytesGSE17611 78491978 78492772 794 0
p63 keratinocytesGSE17611 78578482 78579460 978 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-141 hsa-mir-141 12 20420713
hsa-miR-141* hsa-mir-141 12 20420713
hsa-miR-142-3p hsa-mir-142 17 20420713
hsa-miR-149 hsa-mir-149 2 20420713
hsa-miR-149* hsa-mir-149 2 20420713
hsa-miR-185 hsa-mir-185 22 20420713
hsa-miR-185* hsa-mir-185 22 20420713
hsa-miR-200a* hsa-mir-200a 1 20420713
hsa-miR-200c hsa-mir-200c 12 20420713
hsa-miR-200c* hsa-mir-200c 12 20420713
hsa-miR-21 hsa-mir-21 17 20420713
hsa-miR-21* hsa-mir-21 17 20420713
hsa-miR-211 hsa-mir-211 15 21072171
hsa-miR-224 hsa-mir-224 X 20420713
hsa-miR-34a hsa-mir-34a 1 20420713
hsa-miR-34a* hsa-mir-34a 1 20420713
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
3345 mRNA chr10 78382318 78386891 124 mRNA KCNMA1 chr10 78299364 78833748Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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