AutismKB 2.0

Annotation Detail for KLK1


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Basic Information Top
Gene Symbol:KLK1 ( KLKR,Klk6,hK1 )
Gene Full Name: kallikrein 1
Band: 19q13.33
Quick LinksEntrez ID:3816; OMIM: 147910; Uniprot ID:KLK1_HUMAN; ENSEMBL ID: ENSG00000167748; HGNC ID: 6357
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
93O-linked (GalNAc...).
102N-linked (GlcNAc...).
104O-linked (GalNAc...).
108N-linked (GlcNAc...).
165N-linked (GlcNAc...); partial.
167O-linked (GalNAc...).
Location(AA) Modifications Resource
93O-linked (GalNAc...).Swiss-Prot 53.0
93O-linkedOGlycBase6.0
102N-likedOGlycBase6.0
102N-linked (GlcNAc...).Swiss-Prot 53.0
104O-linked (GalNAc...).Swiss-Prot 53.0
104O-linkedOGlycBase6.0
108N-linked (GlcNAc...).Swiss-Prot 53.0
108N-likedOGlycBase6.0
165N-linked (GlcNAc...); partial.Swiss-Prot 53.0
165N-likedOGlycBase6.0
167O-linked (GalNAc...).Swiss-Prot 53.0
167O-linkedOGlycBase6.0
Location(AA) Modification Resource
108N-linkedHMM predict
151Phosphoserine(PKA)HMM predict
165N-linkedHMM predict
194Phosphothreonine(PKA)HMM predict
232Phosphotyrosine(Jak)HMM predict
258IsoleucineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002257
  • Location:chr19 56014215-56018854
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 56010480 56010877 397 3537
VDR GM10861-stimGSE22484 56011896 56016426 4530 55
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 56018461 56019174 713 0
hScc1 BcellGSE12603 56013866 56015391 1525 0
hScc1 BcellGSE12603 56016647 56016878 231 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7f hsa-let-7f-1 9 20180642
hsa-let-7f hsa-let-7f-2 X 20180642
hsa-let-7f hsa-let-7f-1 9 18627289
hsa-let-7f hsa-let-7f-2 X 18627289
hsa-let-7f hsa-let-7f-1 9 20180642
hsa-let-7f hsa-let-7f-2 X 20180642
hsa-let-7f hsa-let-7f-1 9 18627289
hsa-let-7f hsa-let-7f-2 X 18627289
hsa-let-7f hsa-let-7f-1 9 20180642
hsa-let-7f hsa-let-7f-2 X 20180642
hsa-let-7f hsa-let-7f-1 9 18627289
hsa-let-7f hsa-let-7f-2 X 18627289
hsa-miR-224 hsa-mir-224 X 20180642
hsa-miR-224 hsa-mir-224 X 20180642
hsa-miR-224 hsa-mir-224 X 20180642
No data
Cis-Nats regulation Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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