AutismKB 2.0

Annotation Detail for KLC1


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Basic Information Top
Gene Symbol:KLC1 ( KLC,KNS2,KNS2A,MGC15245 )
Gene Full Name: kinesin light chain 1
Band: 14q32.33
Quick LinksEntrez ID:3831; OMIM: 600025; Uniprot ID:KLC1_HUMAN; ENSEMBL ID: ENSG00000126214; HGNC ID: 6387
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
162Phosphoserine (By similarity).
449Phosphotyrosine (By similarity).
460Phosphoserine.
462Phosphothreonine.
521Phosphoserine.
524Phosphoserine.
Location(AA) Modifications Resource
456Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
22Phosphoserine(CK1)HMM predict
158Phosphoserine(CK2)HMM predict
158Phosphoserine(ATM)HMM predict
267Phosphotyrosine(Syk)HMM predict
351Phosphotyrosine(EGFR)HMM predict
356SulfotyrosineHMM predict
445Phosphotyrosine(INSR)HMM predict
445SulfotyrosineHMM predict
456O-linkedHMM predict
460O-linkedHMM predict
461O-linkedHMM predict
462O-linkedHMM predict
481Phosphothreonine(PKC)HMM predict
541Phosphoserine(CK1)HMM predict
557LysineHMM predict
567ArginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005552
  • Location:chr14 103165277-103222320
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 103160208 103160625 417 4861
CTCF G2GSE9613 103161015 103161465 450 4038
CTCF G2GSE9613 103162135 103162322 187 3049
Oct1 HelaGSE14283 103151263 103151321 58 13986
Oct1 HelaGSE14283 103159390 103159422 32 5872
PHF8 293TGSE20725 103164627 103165922 1295 3
RARA MCF7GSE15244 103163160 103163486 326 1955
RARG MCF7GSE15244 103150301 103150546 245 14854
RARG MCF7GSE15244 103163160 103163486 326 1955
RARG MCF7GSE15244 103163814 103164286 472 1228
hScc1 BcellGSE12603 103162135 103162357 222 3032
hScc1 CdLSGSE12603 103164501 103165173 672 441
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 103165072 103165981 909 0
CTCF G2GSE9613 103215645 103215786 141 0
Myc K562GSE19551 103215417 103215870 453 0
Myc hESGSE17917 103165258 103165626 368 0
Oct1 H2O2-HelaGSE14283 103179014 103179041 27 0
Oct1 H2O2-HelaGSE14283 103186497 103186525 28 0
Oct1 HelaGSE14283 103171070 103171107 37 0
PHF8 HeLaGSE20725 103164284 103166333 2049 0
hScc1 BcellGSE12603 103164989 103166157 1168 0
hScc1 BcellGSE12603 103215426 103215822 396 0
hScc1 CdLSGSE12603 103215462 103216082 620 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
8422 mRNA KNS2 chr14 103165330 103247461 189 mRNA XRCC3 chr14 103233707 103251549Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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