AutismKB 2.0

Annotation Detail for KIF11


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Basic Information Top
Gene Symbol:KIF11 ( EG5,HKSP,KNSL1,TRIP5 )
Gene Full Name: kinesin family member 11
Band: 10q23.33
Quick LinksEntrez ID:3832; OMIM: 148760; Uniprot ID:KIF11_HUMAN; ENSEMBL ID: ENSG00000138160; HGNC ID: 6388
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
146N6-acetyllysine.
458Phosphothreonine.
926Phosphothreonine; by CDK1.
931Phosphoserine.
1029Phosphothreonine.
1033Phosphoserine; by NEK6.
Location(AA) Modifications Resource
926Phosphothreonine (by CDC2).Swiss-Prot 53.0
926Phosphothreonine (CDK1;CDK
931Phosphoserine.Swiss-Prot 53.0
931PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
7Phosphoserine(CDC2)HMM predict
36Phosphoserine(PKG)HMM predict
39Phosphoserine(IKK)HMM predict
98N-linkedHMM predict
125SulfotyrosineHMM predict
125Phosphotyrosine(SRC)HMM predict
150N-linkedHMM predict
159Phosphoserine(PKG)HMM predict
173N-linkedHMM predict
223Phosphothreonine(PKA)HMM predict
237Phosphoserine(IKK)HMM predict
240Phosphoserine(CK1)HMM predict
335O-linkedHMM predict
348Phosphoserine(CK1)HMM predict
370Phosphothreonine(PKC)HMM predict
399Phosphotyrosine(Jak)HMM predict
399Phosphotyrosine(INSR)HMM predict
456N-linkedHMM predict
487PhosphoserineHMM predict
576Phosphoserine(IKK)HMM predict
595N-linkedHMM predict
719Phosphoserine(IKK)HMM predict
780Phosphoserine(ATM)HMM predict
812Phosphoserine(ATM)HMM predict
926Phosphothreonine(CDC2)HMM predict
926Phosphothreonine(MAPK)HMM predict
926Phosphothreonine(CDK)HMM predict
941Phosphothreonine(CDK)HMM predict
992Phosphoserine(ATM)HMM predict
1005Phosphoserine(CK1)HMM predict
1029Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004523
  • Location:chr10 94342970-94405129
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF HelaGSE12889 94340520 94340685 165 2368
ETS1 JurkatGSE17954 94340909 94342039 1130 1497
ETS1 JurkatGSE17954 94342394 94343486 1092 31
H3K4me2 HCT116GSE10453 94339960 94340781 821 2600
H3ac HepG2E 94339960 94340781 821 2600
H3ac HepG2E 94342444 94342759 315 369
PHF8 Hs68minusFBSGSE20725 94342460 94342887 427 297
PHF8 Hs68plusFBSGSE20725 94340910 94341941 1031 1545
PHF8 Hs68plusFBSGSE20725 94342185 94343197 1012 280
TAF HelaGSE8489 94342444 94342801 357 348
TAF k562GSE8489 94342444 94342759 315 369
USF2 HepG2E 94339960 94340185 225 2898
hScc1 BcellGSE12603 94340522 94340781 259 2319
hScc1 CdLSGSE12603 94340415 94340781 366 2373
p130 QuiescentGSE19898 94342440 94343395 955 53
p130 shRbQuiescentGSE19898 94342553 94343370 817 9
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Fulvestrant-MCF7GSE14664 94421317 94421353 36 16206
TFAP2C MCF7GSE21234 94405930 94406508 578 1090
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 G0GSE7516 94342444 94343759 1315 0
ER E2-MCF7GSE14664 94360928 94361009 81 0
ER E2-MCF7GSE14664 94373479 94373511 32 0
ER E2-MCF7GSE14664 94393967 94394001 34 0
ER Fulvestrant-MCF7GSE14664 94393968 94394002 34 0
H3K4me3 colorectalcancer 94342931 94343723 792 0
H3ac HepG2E 94343131 94344688 1557 0
H3ac HepG2E 94346594 94346991 397 0
LIN9 G0GSE7516 94342444 94343933 1489 0
LIN9 SGSE7516 94342444 94344054 1610 0
Myc K562GSE19551 94394273 94394572 299 0
Oct1 H2O2-HelaGSE14283 94360300 94360334 34 0
Oct1 HelaGSE14283 94360301 94360333 32 0
Oct1 HelaGSE14283 94393966 94394001 35 0
Oct1 HelaGSE14283 94396745 94396773 28 0
Rb GrowingGSE19898 94342729 94343260 531 0
TAF HelaGSE8489 94343305 94344091 786 0
TAF HelaGSE8489 94346594 94346991 397 0
TAF k562GSE8489 94343131 94344688 1557 0
TAF k562GSE8489 94346594 94346991 397 0
p130 SenescentGSE19898 94342439 94343970 1531 0
p130 shRbSenescentGSE19898 94342619 94343421 802 0
p130 G0GSE7516 94342444 94343933 1489 0
p130 SGSE7516 94342643 94343377 734 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018