Annotation Detail for KRT18
Basic Information Top
| Gene Symbol: | KRT18 ( CYK18,K18 ) |
|---|---|
| Gene Full Name: | keratin 18 |
| Band: | 12q13.13 |
| Quick Links | Entrez ID:3875; OMIM: 148070; Uniprot ID:K1C18_HUMAN; ENSEMBL ID: ENSG00000111057; HGNC ID: 6430 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 2 | N-acetylserine. | |
| 7 | Phosphoserine. | |
| 8 | Phosphothreonine (By similarity). | |
| 10 | Phosphoserine. | |
| 11 | Phosphothreonine (By similarity). | |
| 13 | Phosphotyrosine. | |
| 15 | Phosphoserine. | |
| 18 | Phosphoserine. | |
| 23 | Phosphoserine. | |
| 30 | Phosphoserine (By similarity). | |
| 30 | O-linked (GlcNAc). | |
| 31 | Phosphoserine. | |
| 31 | O-linked (GlcNAc). | |
| 34 | Phosphoserine; by CDK1. | |
| 36 | Phosphotyrosine. | |
| 42 | Phosphoserine. | |
| 44 | Phosphoserine. | |
| 47 | Phosphoserine. | |
| 49 | O-linked (GlcNAc). | |
| 53 | Phosphoserine; by CAMK, PKC/PRKCE and | |
| 60 | Phosphoserine. | |
| 100 | Phosphoserine. | |
| 111 | N6-acetyllysine. | |
| 131 | N6-acetyllysine. | |
| 167 | N6-acetyllysine. | |
| 302 | Phosphothreonine. | |
| 399 | Phosphoserine. | |
| 401 | Phosphoserine (By similarity). | |
| 404 | Phosphothreonine. | |
| 420 | Phosphoserine. | |
| 426 | N6-acetyllysine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 2 | N-acetylserine. | Swiss-Prot 53.0 |
| 6 | Phosphoserine | Phospho.ELM 6.0 |
| 7 | Phosphoserine (By similarity). | Swiss-Prot 53.0 |
| 8 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 |
| 11 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 |
| 18 | Phosphoserine (By similarity). | Swiss-Prot 53.0 |
| 30 | O-linked (GlcNAc)./FTId=CAR | |
| 30 | Phosphoserine (By similarity). | Swiss-Prot 53.0 |
| 31 | Phosphoserine (By similarity). | Swiss-Prot 53.0 |
| 31 | O-linked (GlcNAc)./FTId=CAR | |
| 33 | Phosphoserine (CDK1) | Phospho.ELM 6.0 |
| 34 | Phosphoserine; by CDC2. | Swiss-Prot 53.0 |
| 36 | Phosphotyrosine (By similarity). | Swiss-Prot 53.0 |
| 42 | Phosphoserine (By similarity). | Swiss-Prot 53.0 |
| 49 | O-linked (GlcNAc)./FTId=CAR | |
| 52 | Phosphoserine (PKC epsilon;) | Phospho.ELM 6.0 |
| 53 | Phosphoserine; by CAMK, PKC/PRKCE andSTK6. | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 30 | Phosphoserine(IKK) | HMM predict |
| 30 | O-linked | HMM predict |
| 31 | O-linked | HMM predict |
| 47 | Phosphoserine(PKA) | HMM predict |
| 49 | O-linked | HMM predict |
| 53 | Phosphoserine(PKB) | HMM predict |
| 55 | Methylarginine | HMM predict |
| 100 | Phosphoserine(CK1) | HMM predict |
| 177 | Phosphoserine(PKG) | HMM predict |
| 193 | N-linked | HMM predict |
| 280 | O-linked | HMM predict |
| 284 | O-linked | HMM predict |
| 284 | O-linked | HMM predict |
| 286 | O-linked | HMM predict |
| 379 | Phosphothreonine(PKC) | HMM predict |
| 423 | N-linked | HMM predict |
- RefSeq ID: NM_000224
- Location:chr12 51629109-51632950
- strand:+
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 51645234 | 51645400 | 166 | 12367 |
| ER | MCF7 | GSE19013 | 51649542 | 51650967 | 1425 | 17304 |
| ER | MCF7 | GSE19013 | 51651355 | 51653347 | 1992 | 19401 |
| FOXA1 | DLD1 | GSE12801 | 51649850 | 51650388 | 538 | 17169 |
| FOXA1 | MCF7 | GSE15244 | 51637068 | 51637250 | 182 | 4209 |
| FOXA1 | MCF7 | GSE15244 | 51649795 | 51650710 | 915 | 17302 |
| FOXA1 | MCF7 | GSE15244 | 51651614 | 51652169 | 555 | 18941 |
| GATA3 | MCF7 | GSE15244 | 51649795 | 51650741 | 946 | 17318 |
| GATA3 | MCF7 | GSE15244 | 51651614 | 51652169 | 555 | 18941 |
| H3ac | HepG2 | E | 51633022 | 51633495 | 473 | 308 |
| Oct1 | Hela | GSE14283 | 51648327 | 51648374 | 47 | 15400 |
| RARA | MCF7 | GSE15244 | 51637068 | 51637250 | 182 | 4209 |
| RARA | MCF7 | GSE15244 | 51649795 | 51650948 | 1153 | 17421 |
| RARA | MCF7 | GSE15244 | 51651614 | 51652169 | 555 | 18941 |
| RARG | MCF7 | GSE15244 | 51637068 | 51637250 | 182 | 4209 |
| RARG | MCF7 | GSE15244 | 51649795 | 51650948 | 1153 | 17421 |
| RARG | MCF7 | GSE15244 | 51651614 | 51652169 | 555 | 18941 |
| TFAP2C | MCF7 | GSE21234 | 51651421 | 51652823 | 1402 | 19172 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CBP | T30-glioblastoma | GSE21026 | 51629539 | 51630302 | 763 | 0 |
| CTCF | G2 | GSE9613 | 51628842 | 51630091 | 1249 | 0 |
| CTCF | G2 | GSE9613 | 51631593 | 51633389 | 1796 | 0 |
| FOXA1 | DLD1 | GSE12801 | 51629789 | 51630258 | 469 | 0 |
| FOXA1 | MCF7 | GSE15244 | 51629356 | 51632555 | 3199 | 0 |
| Fos | K562 | GSE19551 | 51629664 | 51630324 | 660 | 0 |
| FoxA1 | MCF7 | MACSdata | 51629781 | 51630096 | 315 | 0 |
| H3ac | HepG2 | E | 51629502 | 51631932 | 2430 | 0 |
| P300 | T0-glioblastoma | GSE21026 | 51629415 | 51630261 | 846 | 0 |
| P300 | T30-glioblastoma | GSE21026 | 51629626 | 51630454 | 828 | 0 |
| PolII | HeLa | GSE12783 | 51624369 | 51634665 | 10296 | 0 |
| RARA | MCF7 | GSE15244 | 51629432 | 51633848 | 4416 | 0 |
| RARG | MCF7 | GSE15244 | 51629468 | 51633848 | 4380 | 0 |
| hScc1 | G2 | GSE9613 | 51628842 | 51629689 | 847 | 0 |
| hScc1 | G2 | GSE9613 | 51631629 | 51632410 | 781 | 0 |
Validated miRNA targets| Cluster ID | Plue Type | Plus Gene Name | Plus Chromosome | Plus Start | Plus End | Overlap Length | Minus Type | Minus Gene Name | Minus Chromosome | Minus Star | Minus End | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 6045 | mRNA | KRT18 | chr12 | 51629109 | 51632951 | 135 | EST | chr12 | 51584901 | 51629893 | Sense/Antisense (SA) pairs | |