AutismKB 2.0

Annotation Detail for LAMA2


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Basic Information Top
Gene Symbol:LAMA2 ( LAMM )
Gene Full Name: laminin, alpha 2
Band: 6q22.33
Quick LinksEntrez ID:3908; OMIM: 156225; Uniprot ID:LAMA2_HUMAN; ENSEMBL ID: ENSG00000196569; HGNC ID: 6482
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
55N-linked (GlcNAc...) (Potential).
89N-linked (GlcNAc...) (Potential).
303N-linked (GlcNAc...) (Potential).
363N-linked (GlcNAc...).
380N-linked (GlcNAc...) (Potential).
470N-linked (GlcNAc...) (Potential).
746N-linked (GlcNAc...) (Potential).
1061N-linked (GlcNAc...) (Potential).
1597N-linked (GlcNAc...) (Potential).
1614N-linked (GlcNAc...) (Potential).
1700N-linked (GlcNAc...) (Potential).
1810N-linked (GlcNAc...) (Potential).
1901N-linked (GlcNAc...).
1916N-linked (GlcNAc...).
1920N-linked (GlcNAc...).
2017N-linked (GlcNAc...).
2028N-linked (GlcNAc...) (Potential).
2045N-linked (GlcNAc...) (Potential).
2126N-linked (GlcNAc...) (Potential).
2240N-linked (GlcNAc...) (Potential).
2360N-linked (GlcNAc...) (Potential).
2435N-linked (GlcNAc...) (Potential).
2478N-linked (GlcNAc...) (Potential).
2551N-linked (GlcNAc...) (Potential).
2558N-linked (GlcNAc...) (Potential).
2648N-linked (GlcNAc...).
2868N-linked (GlcNAc...) (Potential).
2893N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
55N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
89N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
303N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
363N-linked (GlcNAc...).Swiss-Prot 53.0
380N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
470N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
746N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1061N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1597N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1614N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1700N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1810N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1901N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1916N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1920N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2017N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2028N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2045N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2126N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2240N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2360N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2435N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2478N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2551N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2558N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2648N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2868N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2893N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
55N-linkedHMM predict
89N-linkedHMM predict
92N-linkedHMM predict
94N-linkedHMM predict
146PhosphoserineHMM predict
163SulfotyrosineHMM predict
271Phosphothreonine(PKC)HMM predict
303N-linkedHMM predict
321S-palmitoylHMM predict
322S-palmitoylHMM predict
380N-linkedHMM predict
384N-linkedHMM predict
470N-linkedHMM predict
608SulfotyrosineHMM predict
642Phosphotyrosine(Syk)HMM predict
746N-linkedHMM predict
757S-palmitoylHMM predict
817N-linkedHMM predict
839Phosphotyrosine(Abl)HMM predict
881Phosphoserine(CK1)HMM predict
881Phosphoserine(IKK)HMM predict
885Phosphoserine(IKK)HMM predict
932Phosphoserine(IKK)HMM predict
932Phosphoserine(CK1)HMM predict
932PhosphoserineHMM predict
982PhosphoserineHMM predict
1014S-palmitoylHMM predict
1061N-linkedHMM predict
1171O-linkedHMM predict
1352Phosphoserine(PKG)HMM predict
1371Phosphothreonine(MAPK)HMM predict
1371Phosphothreonine(CDK)HMM predict
1409Phosphothreonine(MAPK)HMM predict
1409Phosphothreonine(CDK)HMM predict
1420S-palmitoylHMM predict
1479N-linkedHMM predict
1492Phosphotyrosine(INSR)HMM predict
1492Phosphotyrosine(EGFR)HMM predict
1514O-linkedHMM predict
1516Phosphoserine(CDK)HMM predict
1516O-linkedHMM predict
1516Phosphoserine(CDC2)HMM predict
1597N-linkedHMM predict
1614N-linkedHMM predict
1624Phosphoserine(CDC2)HMM predict
1655Phosphothreonine(PKA)HMM predict
1658O-linkedHMM predict
1673Phosphothreonine(PKC)HMM predict
1677Phosphoserine(PKG)HMM predict
1700N-linkedHMM predict
1878Phosphoserine(ATM)HMM predict
1891Phosphoserine(IKK)HMM predict
1891Phosphoserine(ATM)HMM predict
1901N-linkedHMM predict
1920N-linkedHMM predict
1934Phosphotyrosine(INSR)HMM predict
2017N-linkedHMM predict
2028N-linkedHMM predict
2045N-linkedHMM predict
2126N-linkedHMM predict
2147Phosphoserine(PKG)HMM predict
2240N-linkedHMM predict
2262O-linkedHMM predict
2264O-linkedHMM predict
2268Phosphotyrosine(Jak)HMM predict
2348Phosphotyrosine(INSR)HMM predict
2406O-linkedHMM predict
2452Phosphoserine(CDC2)HMM predict
2475Phosphothreonine(PKC)HMM predict
2558N-linkedHMM predict
2570Phosphothreonine(CDC2)HMM predict
2581Phosphothreonine(PKA)HMM predict
2581Phosphothreonine(PKC)HMM predict
2581Phosphothreonine(PKA)HMM predict
2605Phosphothreonine(PKC)HMM predict
2648N-linkedHMM predict
2672Phosphoserine(CDC2)HMM predict
2736O-linkedHMM predict
2741O-linkedHMM predict
2741O-linkedHMM predict
2741Phosphothreonine(MAPK)HMM predict
2741Phosphothreonine(CDC2)HMM predict
2743O-linkedHMM predict
2868N-linkedHMM predict
2872Phosphoserine(CDC2)HMM predict
2872Phosphoserine(CDK)HMM predict
2893N-linkedHMM predict
2905Phosphoserine(IKK)HMM predict
2970O-linkedHMM predict
3057Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000426
  • Location:chr6 129246034-129879400
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 129226262 129226290 28 19759
Oct1 HelaGSE14283 129226262 129226290 28 19759
Rb GrowingGSE19898 129245799 129246083 284 94
p130 QuiescentGSE19898 129245882 129246163 281 12
p130 SenescentGSE19898 129245892 129246051 159 63
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 129883213 129883425 212 3919
p63 keratinocytesGSE17611 129884588 129885280 692 5534
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 129615009 129615235 226 0
CTCF CD4SISSRdata 129615009 129615235 226 0
CTCF G2GSE9613 129360931 129361149 218 0
CTCF G2GSE9613 129614947 129615245 298 0
CTCF G2GSE9613 129673365 129673924 559 0
CTCF G2GSE9613 129733268 129733704 436 0
CTCF G2GSE9613 129861542 129862046 504 0
ER E2-MCF7GSE14664 129512482 129512514 32 0
ER Fulvestrant-MCF7GSE14664 129408160 129408194 34 0
ER MCF7E 129267611 129267962 351 0
Fos K562GSE19551 129853218 129854610 1392 0
Gata2 K562GSE18868 129870724 129871058 334 0
Nanog ESGSE20650 129535552 129535780 228 0
Nanog ESGSE20650 129680956 129681692 736 0
Nanog ESGSE20650 129701634 129701982 348 0
Nanog hESGSE18292 129317452 129317998 546 0
Nanog hESGSE18292 129392667 129392982 315 0
Oct1 H2O2-HelaGSE14283 129496551 129496591 40 0
Oct1 H2O2-HelaGSE14283 129534004 129534043 39 0
Oct1 HelaGSE14283 129336931 129336962 31 0
Oct1 HelaGSE14283 129386453 129386499 46 0
Oct1 HelaGSE14283 129449714 129449749 35 0
Oct1 HelaGSE14283 129496552 129496584 32 0
Oct1 HelaGSE14283 129534005 129534043 38 0
Oct1 HelaGSE14283 129574730 129574757 27 0
Oct1 HelaGSE14283 129586277 129586312 35 0
Oct1 HelaGSE14283 129647820 129647848 28 0
Oct1 HelaGSE14283 129654518 129654556 38 0
Oct1 HelaGSE14283 129681772 129681811 39 0
P300 T0-glioblastomaGSE21026 129614957 129615411 454 0
P300 T0-glioblastomaGSE21026 129681039 129681707 668 0
P300 T30-glioblastomaGSE21026 129703763 129704214 451 0
P300 T30-glioblastomaGSE21026 129853138 129854535 1397 0
PolII HeLaGSE12783 129853133 129854290 1157 0
Rb GrowingGSE19898 129862075 129862206 131 0
STAT1 HeLaGSE12782 129633788 129634823 1035 0
STAT1 HeLaGSE12783 129633666 129634753 1087 0
STAT1 HeLaGSE12783 129705744 129706658 914 0
STAT1 IFNSISSRdata 129633854 129634452 598 0
TAF HelaGSE8489 129853321 129854292 971 0
TFAP2C MCF7GSE21234 129294917 129295245 328 0
TFAP2C MCF7GSE21234 129853795 129854273 478 0
TFAP2C MCF7GSE21234 129864128 129864609 481 0
hScc1 BcellGSE12603 129614852 129615589 737 0
hScc1 BcellGSE12603 129739301 129739579 278 0
hScc1 BcellGSE12603 129861647 129862268 621 0
hScc1 CdLSGSE12603 129614818 129615404 586 0
hScc1 CdLSGSE12603 129861647 129862341 694 0
hScc1 G2GSE9613 129614818 129615404 586 0
hScc1 G2GSE9613 129733196 129733807 611 0
hScc1 G2GSE9613 129861470 129862046 576 0
p130 shRbQuiescentGSE19898 129853412 129854246 834 0
p63 keratinocytesGSE17611 129715796 129716619 823 0
p63 keratinocytesGSE17611 129869899 129870662 763 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
23154 mRNA LAMA2 chr6 129246034 129879401 360 mRNA chr6 129842450 129915424Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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