Annotation Detail for FRRS1

View Evidences	View Variants	View Annotations

Basic Information Top

Gene Symbol:	FRRS1 ( SDFR2,SDR2 )
Gene Full Name:	ferric-chelate reductase 1
Band:	1p21.2
Quick Links	Entrez ID:391059; OMIM: 611578; Uniprot ID:FRRS1_HUMAN; ENSEMBL ID: ENSG00000156869; HGNC ID: 27622
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:3 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:0 results

Location(AA)	Modification
138	N-linked (GlcNAc...) (Potential).
308	N-linked (GlcNAc...) (Potential).
321	N-linked (GlcNAc...) (Potential).

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_001013660
Location:chr1 99946846-100003936
strand:-

Upstream the gene:6 results
Downstream the gene:5 results
Inside the gene:9 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
H3ac	HepG2	E	100004094	100005104	1010	663
NFkBII	GM12878	GSE19485	100022175	100023915	1740	19109
PolII	HeLa	GSE12783	100004280	100005511	1231	959
RARA	MCF7	GSE15244	100004571	100005235	664	967
TAF	k562	GSE8489	100004094	100005235	1141	728
TFAP2C	MCF7	GSE21234	100004594	100004975	381	848

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	99945806	99946033	227	927
CTCF	CD4	SISSRdata	99945806	99946033	227	927
CTCF	G2	GSE9613	99945587	99945993	406	1057
hScc1	CdLS	GSE12603	99945481	99946065	584	1074
hScc1	G2	GSE9613	99945519	99946065	546	1055

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	99967152	99967331	179	0
CTCF	G2	GSE9613	99975070	99975498	428	0
H3ac	HepG2	E	100000668	100001275	607	0
H3ac	HepG2	E	100002677	100003420	743	0
Myc	K562	GSE19551	99983875	99984257	382	0
RARA	MCF7	GSE15244	99994814	99995199	385	0
TAF	k562	GSE8489	100002975	100003420	445	0
hScc1	G2	GSE9613	99974999	99975533	534	0
p63	keratinocytes	GSE17611	100002103	100002705	602	0

Validated miRNA targets

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved