AutismKB 2.0

Annotation Detail for LAMB1


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Basic Information Top
Gene Symbol:LAMB1 ( CLM,MGC142015 )
Gene Full Name: laminin, beta 1
Band: 7q31.1
Quick LinksEntrez ID:3912; OMIM: 150240; Uniprot ID:LAMB1_HUMAN; ENSEMBL ID: ENSG00000091136; HGNC ID: 6486
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
120N-linked (GlcNAc...) (Potential).
356N-linked (GlcNAc...) (Potential).
519N-linked (GlcNAc...) (Potential).
677N-linked (GlcNAc...) (Potential).
1041N-linked (GlcNAc...) (Potential).
1195N-linked (GlcNAc...) (Potential).
1279N-linked (GlcNAc...).
1336N-linked (GlcNAc...) (Potential).
1343N-linked (GlcNAc...) (Potential).
1487N-linked (GlcNAc...) (Potential).
1542N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
120N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
356N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
519N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
677N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1041N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1195N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1279N-linked (GlcNAc...).Swiss-Prot 53.0
1336N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1343N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1487N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1542N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
51Phosphoserine(IKK)HMM predict
85Phosphotyrosine(Syk)HMM predict
120N-linkedHMM predict
195Phosphoserine(CK1)HMM predict
259Phosphotyrosine(Syk)HMM predict
356N-linkedHMM predict
405Phosphoserine(ATM)HMM predict
474Phosphoserine(CK1)HMM predict
519N-linkedHMM predict
520N-linkedHMM predict
640O-linkedHMM predict
658Phosphoserine(CDC2)HMM predict
677N-linkedHMM predict
692Phosphoserine(CK2)HMM predict
737Phosphotyrosine(EGFR)HMM predict
752Phosphothreonine(PKA)HMM predict
783Phosphoserine(IKK)HMM predict
864S-palmitoylHMM predict
965N-linkedHMM predict
1041N-linkedHMM predict
1195N-linkedHMM predict
1210O-linkedHMM predict
1219Phosphothreonine(PKC)HMM predict
1228Phosphoserine(PKG)HMM predict
1228Phosphoserine(CAMK2)HMM predict
1272Phosphoserine(PKG)HMM predict
1276Phosphoserine(CK1)HMM predict
1276Phosphoserine(IKK)HMM predict
1276O-linkedHMM predict
1276Phosphoserine(ATM)HMM predict
1279N-linkedHMM predict
1290Phosphothreonine(PKC)HMM predict
1336N-linkedHMM predict
1343N-linkedHMM predict
1487N-linkedHMM predict
1520Phosphoserine(CK1)HMM predict
1542N-linkedHMM predict
1553Phosphoserine(CK1)HMM predict
1555Phosphoserine(CK1)HMM predict
1632Phosphoserine(CK2)HMM predict
1671Phosphotyrosine(EGFR)HMM predict
1682Phosphoserine(PKG)HMM predict
1698Phosphotyrosine(Syk)HMM predict
1753Phosphotyrosine(Syk)HMM predict
1775IsoleucineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002291
  • Location:chr7 107351498-107431039
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 107431166 107432804 1638 946
p130 QuiescentGSE19898 107435012 107435260 248 4097
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FoxA1 MCF7MACSdata 107350627 107350746 119 812
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 107359935 107360087 152 0
CTCF G2GSE9613 107429374 107430976 1602 0
FOXA1 MCF7GSE15244 107376571 107377569 998 0
FOXA1 MCF7GSE15244 107379144 107380719 1575 0
FOXA1 MCF7GSE15244 107394239 107395742 1503 0
FoxA1 MCF7MACSdata 107395171 107395409 238 0
Nanog ESGSE20650 107387150 107387596 446 0
Oct1 H2O2-HelaGSE14283 107384826 107384867 41 0
Oct1 HelaGSE14283 107384703 107384737 34 0
Oct1 HelaGSE14283 107384833 107384866 33 0
Oct1 HelaGSE14283 107395584 107395688 104 0
RARA MCF7GSE15244 107376517 107377569 1052 0
RARA MCF7GSE15244 107379113 107380719 1606 0
RARA MCF7GSE15244 107422770 107424781 2011 0
Rb GrowingGSE19898 107410880 107411094 214 0
Rb GrowingGSE19898 107430720 107430935 215 0
STAT1 HeLaGSE12783 107422662 107424225 1563 0
Stat6 IL-4-hr4GSE17850 107429006 107429586 580 0
TFAP2C MCF7GSE21234 107376774 107377603 829 0
TFAP2C MCF7GSE21234 107379504 107379980 476 0
TFAP2C MCF7GSE21234 107380127 107380869 742 0
TFAP2C MCF7GSE21234 107390522 107390955 433 0
hScc1 G2GSE9613 107429339 107431475 2136 0
p130 QuiescentGSE19898 107430545 107430817 272 0
p130 SenescentGSE19898 107399698 107400132 434 0
p130 SenescentGSE19898 107429687 107430101 414 0
p130 shRbQuiescentGSE19898 107403987 107404436 449 0
p130 shRbSenescentGSE19898 107430678 107430934 256 0
p63 keratinocytesGSE17611 107365153 107365898 745 0
p63 keratinocytesGSE17611 107400500 107401290 790 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018