Annotation Detail for LAMC2
Basic Information Top
| Gene Symbol: | LAMC2 ( B2T,BM600,CSF,EBR2,EBR2A,LAMB2T,LAMNB2,MGC138491,MGC141938 ) |
|---|---|
| Gene Full Name: | laminin, gamma 2 |
| Band: | 1q25.3 |
| Quick Links | Entrez ID:3918; OMIM: 150292; Uniprot ID:LAMC2_HUMAN; ENSEMBL ID: ENSG00000058085; HGNC ID: 6493 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 250 | Phosphotyrosine. | |
| 265 | Phosphotyrosine. | |
| 273 | Phosphotyrosine. | |
| 342 | N-linked (GlcNAc...) (Potential). | |
| 362 | N-linked (GlcNAc...) (Potential). | |
| 942 | N-linked (GlcNAc...) (Potential). | |
| 1033 | N-linked (GlcNAc...) (Potential). | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 342 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 362 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 942 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 1033 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 8 | S-palmitoyl | HMM predict |
| 9 | S-palmitoyl | HMM predict |
| 22 | Phosphothreonine(PKC) | HMM predict |
| 84 | S-palmitoyl | HMM predict |
| 198 | Phosphoserine(CK1) | HMM predict |
| 202 | Phosphotyrosine(SRC) | HMM predict |
| 224 | N-linked | HMM predict |
| 226 | Phosphoserine(CDC2) | HMM predict |
| 283 | Phosphoserine(PKB) | HMM predict |
| 342 | N-linked | HMM predict |
| 359 | Phosphotyrosine(INSR) | HMM predict |
| 362 | N-linked | HMM predict |
| 372 | O-linked | HMM predict |
| 433 | Phosphoserine(IKK) | HMM predict |
| 535 | Phosphothreonine(PKA) | HMM predict |
| 538 | S-palmitoyl | HMM predict |
| 612 | S-palmitoyl | HMM predict |
| 701 | Phosphothreonine(PKC) | HMM predict |
| 785 | Phosphotyrosine(Syk) | HMM predict |
| 805 | O-linked | HMM predict |
| 807 | Phosphoserine(CDC2) | HMM predict |
| 825 | Phosphoserine(IKK) | HMM predict |
| 880 | Phosphoserine(CK1) | HMM predict |
| 882 | Phosphoserine(CK1) | HMM predict |
| 942 | N-linked | HMM predict |
| 980 | Phosphoserine(ATM) | HMM predict |
| 1019 | Phosphoserine(CK2) | HMM predict |
| 1019 | Phosphoserine(CK1) | HMM predict |
| 1033 | N-linked | HMM predict |
| 1079 | Phosphothreonine(CK2) | HMM predict |
| 1114 | Phosphoserine(CK2) | HMM predict |
| 1185 | Tyrosine | HMM predict |
- RefSeq ID: NM_005562
- Location:chr1 181422021-181480661
- strand:+
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| Oct1 | H2O2-Hela | GSE14283 | 181481336 | 181481364 | 28 | 689 |
| No data |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-let-7b | hsa-let-7b | 22 | 15131085 |
| hsa-let-7b* | hsa-let-7b | 22 | 15131085 |
| hsa-let-7e | hsa-let-7e | 19 | 15131085 |
| hsa-let-7e* | hsa-let-7e | 19 | 15131085 |
| hsa-miR-103 | hsa-mir-103-2 | 20 | 15131085 |
| hsa-miR-103 | hsa-mir-103-1 | 5 | 15131085 |
| hsa-miR-141 | hsa-mir-141 | 12 | 15131085 |
| hsa-miR-141* | hsa-mir-141 | 12 | 15131085 |
| hsa-miR-145 | hsa-mir-145 | 5 | 15131085 |
| hsa-miR-145* | hsa-mir-145 | 5 | 15131085 |
| hsa-miR-15a | hsa-mir-15a | 13 | 15131085 |
| hsa-miR-15a* | hsa-mir-15a | 13 | 15131085 |
| hsa-miR-15b | hsa-mir-15b | 3 | 15131085 |
| hsa-miR-15b* | hsa-mir-15b | 3 | 15131085 |
| hsa-miR-16 | hsa-mir-16-1 | 13 | 15131085 |
| hsa-miR-16 | hsa-mir-16-2 | 3 | 15131085 |
| hsa-miR-199b-3p | hsa-mir-199b | 9 | 15131085 |
| hsa-miR-199b-5p | hsa-mir-199b | 9 | 15131085 |
| hsa-miR-19a | hsa-mir-19a | 13 | 21200023 |
| hsa-miR-19a* | hsa-mir-19a | 13 | 21200023 |
| hsa-miR-19b | hsa-mir-19b-1 | 13 | 21200023 |
| hsa-miR-19b | hsa-mir-19b-2 | X | 21200023 |
| hsa-miR-19b-1* | hsa-mir-19b-1 | 13 | 21200023 |
| hsa-miR-19b-2* | hsa-mir-19b-2 | X | 21200023 |
| hsa-miR-21 | hsa-mir-21 | 17 | 21200023 |
| hsa-miR-21* | hsa-mir-21 | 17 | 21200023 |
| hsa-miR-23a | hsa-mir-23a | 19 | 15131085 |
| hsa-miR-23a* | hsa-mir-23a | 19 | 15131085 |
| hsa-miR-24 | hsa-mir-24-1 | 9 | 15131085 |
| hsa-miR-24 | hsa-mir-24-2 | 19 | 15131085 |
| hsa-miR-449a | hsa-mir-449a | 5 | 19056356 |
| hsa-miR-449b | hsa-mir-449b | 5 | 19056356 |
| hsa-miR-92a | hsa-mir-92a-1 | 13 | 21200023 |
| hsa-miR-92a | hsa-mir-92a-2 | X | 21200023 |
| ID in Tarbase | Data Type | Support Type | miRNA | Gene | Direct Support | Publication |
|---|---|---|---|---|---|---|
| 505 | mRNA repression | TRUE | miR-199b | LAMC2 | in vitro reporter gene assay (Luciferase) | 15131085 |
| Ensembl | Protein Type | Differentially expressed in | Pathology or Event | Mis Regulation | Gene Expression | Tumour Involvement |
| ENSG00000058085 | n_a | n_a | n_a | "epithelium, lymphocyte, muscle cell" | "benign tumour, malignant tumour, carcinoma, sarcoma" |
| Cluster ID | Plue Type | Plus Gene Name | Plus Chromosome | Plus Start | Plus End | Overlap Length | Minus Type | Minus Gene Name | Minus Chromosome | Minus Star | Minus End | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2046 | mRNA | LAMC2 | chr1 | 179887055 | 179945696 | 66 | EST | chr1 | 179933150 | 179936432 | Sense/Antisense (SA) pairs | |