AutismKB 2.0

Annotation Detail for ARHGAP1


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Basic Information Top
Gene Symbol:ARHGAP1 ( CDC42GAP,RHOGAP,RHOGAP1,p50rhoGAP )
Gene Full Name: Rho GTPase activating protein 1
Band: 11p11.2
Quick LinksEntrez ID:392; OMIM: 602732; Uniprot ID:RHG01_HUMAN; ENSEMBL ID: ENSG00000175220; HGNC ID: 673
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1N-acetylmethionine.
51Phosphoserine.
65Phosphotyrosine (By similarity).
80N6-acetyllysine.
212N6-acetyllysine.
238SH3-binding.
Location(AA) Modifications Resource
Location(AA) Modification Resource
44Phosphoserine(CK2)HMM predict
47Phosphoserine(CK1)HMM predict
47Phosphoserine(IKK)HMM predict
49Phosphoserine(CK2)HMM predict
50Phosphoserine(CK1)HMM predict
64Phosphotyrosine(Syk)HMM predict
65Phosphotyrosine(Syk)HMM predict
81Phosphotyrosine(EGFR)HMM predict
107Phosphotyrosine(Jak)HMM predict
115SulfotyrosineHMM predict
223Phosphoserine(CDC2)HMM predict
308Phosphotyrosine(Syk)HMM predict
347Phosphoserine(ATM)HMM predict
359Phosphothreonine(PKC)HMM predict
365Phosphotyrosine(SRC)HMM predict
365Phosphotyrosine(Syk)HMM predict
433Phosphoserine(CDK)HMM predict
433Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004308
  • Location:chr11 46655207-46678695
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 46678723 46678855 132 94
CTCF CD4SISSRdata 46678723 46678855 132 94
FOXA1 MCF7GSE15244 46678297 46679283 986 95
SRF HelaGSE8489 46678297 46679283 986 95
p130 QuiescentGSE19898 46678542 46679070 528 111
p130 shRbQuiescentGSE19898 46678336 46679264 928 105
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 46675976 46676229 253 0
H3ac HepG2E 46676751 46677402 651 0
H3ac HepG2E 46678297 46678498 201 0
NRSF pAbJurkat 46675404 46675914 510 0
RARG MCF7GSE15244 46665481 46665844 363 0
Rb QuiescentGSE19898 46678405 46678969 564 0
Rb SenescentGSE19898 46678242 46679105 863 0
Rb shRbSenescenceGSE19898 46678458 46678698 240 0
SRF k562GSE8489 46678297 46678498 201 0
hScc1 BcellGSE12603 46655434 46655687 253 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
4385 mRNA chr11 46654654 46655254 45 mRNA ARHGAP1 chr11 46655209 46678696Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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