AutismKB 2.0

Annotation Detail for LCAT


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Basic Information Top
Gene Symbol:LCAT ( - )
Gene Full Name: lecithin-cholesterol acyltransferase
Band: 16q22.1
Quick LinksEntrez ID:3931; OMIM: 606967; Uniprot ID:LCAT_HUMAN; ENSEMBL ID: ENSG00000213398; HGNC ID: 6522
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
44N-linked (GlcNAc...) (Complex).
108N-linked (GlcNAc...) (Complex).
296N-linked (GlcNAc...) (Complex).
408N-linked (GlcNAc...) (Complex).
431O-linked (GalNAc...).
433O-linked (GalNAc...).
Location(AA) Modifications Resource
44N-linked (GlcNAc...).Swiss-Prot 53.0
44N-likedOGlycBase6.0
108N-linked (GlcNAc...).Swiss-Prot 53.0
108N-likedOGlycBase6.0
205PhosphoserinePhospho.ELM 6.0
296N-linked (GlcNAc...).Swiss-Prot 53.0
296N-likedOGlycBase6.0
408N-linked (GlcNAc...).Swiss-Prot 53.0
408N-likedOGlycBase6.0
431O-linked (GalNAc...).Swiss-Prot 53.0
431O-linkedOGlycBase6.0
433O-linked (GalNAc...).Swiss-Prot 53.0
433O-linkedOGlycBase6.0
Location(AA) Modification Resource
37PhosphothreonineHMM predict
37Phosphothreonine(CDC2)HMM predict
44N-linkedHMM predict
162Phosphothreonine(PKC)HMM predict
180Phosphotyrosine(Jak)HMM predict
181Phosphotyrosine(EGFR)HMM predict
181Phosphotyrosine(Jak)HMM predict
296N-linkedHMM predict
316Phosphotyrosine(SRC)HMM predict
345Phosphothreonine(MAPK)HMM predict
377Phosphothreonine(PKA)HMM predict
408N-linkedHMM predict
429Phosphoserine(CDC2)HMM predict
429PhosphoserineHMM predict
429O-linkedHMM predict
429Phosphoserine(MAPK)HMM predict
431O-linkedHMM predict
431O-linkedHMM predict
433Phosphoserine(ATM)HMM predict
433Phosphoserine(CDC2)HMM predict
433O-linkedHMM predict
438ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000229
  • Location:chr16 66531287-66535515
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 66530925 66531222 297 214
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 66533520 66533802 282 0
CTCF CD4SISSRdata 66533520 66533802 282 0
CTCF JurkatGSE12889 66533602 66533766 164 0
CTCF G2GSE9613 66533113 66534150 1037 0
CTCF G2GSE9613 66534794 66535259 465 0
hScc1 BcellGSE12603 66533349 66534212 863 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018